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  • PharmaTutor
    13 February 2013

    REVIEW ON STEM CELL THERAPY FOR DIABETES

    About Author:
    Kambham Venkateswarlu
    Final Year Graduate Student
    Sri Lakshmi Narasimha College of Pharmacy,
    Palluru, Chittoor-517132, Andhra Pradesh, India.
    k.v.reddy9441701016@gmail.com

    ABSTRACT:
    It is the branch of medicine that involves introducing new cells into a diseased tissue to trigger the body’s ability to heal itself.
    Cell therapy includes stem cell therapy, which means harvesting, transplantating or implanting stem cells in order to make healing mechanisms available in the diseased or damaged tissue itself. These stem cells may be harvested from the body of the mature adult from specialized sites where it is available such as the marrow of large bones or they may be preserved stem cells, harvested from the Umbilical cord blood or cord tissue at the time of that person’s birth.
    They may also be from another donor. If the donor of the stem cells is the same as the patient in whom it is transplanted, it is called autologous cell therapy. If the donor is a different person, it is called allogenic stem cell therapy.

  • HERBS AND THEIR INTERACTION WITH ALLOPATHIC DRUGS – A REVIEW
    12 February 2013
    HERBS AND THEIR INTERACTION WITH ALLOPATHIC DRUGS – A REVIEW

    About Authors:
    Sharma Monish*, Kumar Bhupender, Bhardwaj Sudeep
    Seth G.L Bihani S. D. College of Technical Education,
    Institute of Pharmaceutical Sciences & Drug Research.
    Sri Ganganagar, Rajasthan (INDIA)
    *monish28sharma@gmail.com

    ABSTRACT :
    During the recent past, a dramatic rise in the use of herbs and herbal remedies has been witnessed in many parts of the world.  While such products had been used with apparent safety in traditional societies for many centuries, when they are being combined with pharmacological agents, posses the possibility of potential interaction between the two groups of substances. In this situation, herb-allopathic drug interaction is an important factor to be measured because there is always a chance to get undesirable therapeutic effect of the prescribed allopathic drug, as like allopathic (prescription) drugs. Herbal medicines also have different pharmacokinetic and pharmacodynamic properties which ultimately lead to produce therapeutic responses, but sometimes cause adverse actions and/or drug-herbal interactions. Drug interaction refers to the situation where two or more separate drugs have been absorbed into the body and their effects are affected by each other, i.e. the effects are increased or they produce a new effect that neither produces on its own. The aim of this article is to highlight the interactions between herbal remedies and prescribed drugs.

  • THE ROLE OF COX-2 INHIBITORS IN HUMAN CANCER PREVENTION AND OTHER NOVEL TARGETS - A RECENT REVIEW
    11 February 2013
    THE ROLE OF COX-2 INHIBITORS IN HUMAN CANCER PREVENTION AND OTHER NOVEL TARGETS - A RECENT REVIEW

    About Authors:
    Lohithasu Duppala*1, Madhu priya Damuluri1, Anil kumar vadda2
    1    GITAM Institute of Pharmacy, GITAM University, Pharmaceutics, visakhapatnam, Andhra Pradesh, India-530045.
    2    AVANTHI Institute of pharmaceutical sciences, pharmacology, visakhapatnam, Andhra Pradesh, India-530045.
    *    lohithasu@gmail.com, anilkumar.vadda@gmail.com

    ABSTRACT:
    COX-2 (Cyclooxygenase-2) is a selective inhibitor of non-steroidal anti-inflammatory drug (NSAID). Cyclooxygenase -2, an enzyme responsible for inflammation and pain. Celecoxib, Rofecoxib, valdecoxib, Parecoxib are class of COX-2 inhibiting drugs. COX-2  inhibitors have been revealed to reduce the occurrence of cancers and pre-cancerous growths. Celecoxib, cox-2 inhibitor isused to prevention of polyp formation in Familial Adenomatous Polyposis (FAP). COX-2 inhibitors like celecoxib, Rofecoxib, valdecoxib, Parecoxibare currently being studied in  cancer treatment and other targets. This review highlights the COX-2 inhibitors with special emphasis on their role in various kinds of cancer prevention and other targeted therapy. COX-2 inhibitors in cancer chemotherapy and neurological diseases like Parkinson and Alzheimer’s diseases still continues to attract researches on the development of COX-2 inhibitors.

  • ICH GUIDELINES OF STABILITY DATA: A REVIEW
    10 February 2013
    ICH GUIDELINES OF STABILITY DATA: A REVIEW

    About Authors:
    Kambham Venkateswarlu
    Final Year Graduate Student
    Sri Lakshmi Narasimha College of Pharmacy,
    Palluru, Chittoor-517132, Andhra Pradesh, India.
    k.v.reddy9441701016@gmail.com

    ABSTRACT:
    The International Conference on Harmonization of technical requirements of pharmaceuticals for human use was established in 1990 as a tripartite venture representing regulatory bodies and research based industry. The major aim of ICH is to provide a forum for constructive discussion on the real and perceived differences in technical requirements for the registration of new chemical entities. Other objectives are: To achieve greater harmonization in the interpretation and application of technical guidelines for the registration of new active substances or products obtained by biotechnology by its members; to improve the efficiency of global drug development; to reduce redundant studies; and to improve pharmacovigilance activities and quality assurance.

  • REVIEW ON BALANCED DIET
    6 February 2013
    REVIEW ON BALANCED DIET

    About Author:
    Kambham Venkateswarlu
    Final Year Graduate Student
    Sri Lakshmi Narasimha College of Pharmacy,
    Palluru, Chittoor-517132, Andhra Pradesh, India.
    k.v.reddy9441701016@gmail.com

    ABSTRACT:
    The diet is selection of food eaten by an individual. A balanced diet is essential for health. It provides the appropriate amounts of all nutrients in the correct proportions to meet body requirements.
    An essential nutrient is substances that cannot be made by the body and must be supplied through the diet. Foods are described as carbohydrate or protein because they contain a higher proportion of one or the other. A balanced diet contains all nutrients required for health in appropriate proportions and is normally achieved by eating a variety of foods.

  • A REVIEW ON: FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET
    1 February 2013
    A REVIEW ON: FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET

    About Authors:
    Nishtha Tiwari
    Department of pharmacy,
    b.u Bhopal (m.p.), India
    Nishthatiwari.18@gmail.com

    ABSTRACT
    The oral route of drug administration is the most important method for administering drugs for systemic effects. Except in certain cases the parenteral route is not routinely used for self administration, e.g. insulin. The topical route of administration has only recently been employed to deliver drugs to the body for systemic effects. The parenteral route of administration is important in treating medical emergencies in which the subject is comatose or cannot swallow. Nevertheless it is probable that at least 90% of all drugs used to provide systemic effects are administered by the oral route.

  • BETA-LACTAM CLASS OF DRUGS : A REVIEW
    29 January 2013
    BETA-LACTAM CLASS OF DRUGS : A REVIEW

    About Authors:
    Mayure.Vijay Kumar*, V. Sravanthi Yadav, C.P.Meher,
    Department of pharmaceutical chemistry
    Maheshwara College of Pharmacy, Chitkul (V)
    Isnapur “X” Road, Patancheru, Hyderabad.
    mayurevijaykumar@gmail.com

    ABSTRACT:-
    β- lactam antibiotics are  the most commonly prescribed drugs. The β- lactam group of antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a β- lactam nucleus in their molecular structures. This includes penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems. Most of the β- lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organisms and are the most widely used group of antibiotics. Bacteria often develop resistance to β- lactam antibiotics by synthesizing that attacks the β- lactam ring. To overcome this resistance, β- lactam antibiotics are often given with β- lactamase inhibitors such as clavulanic acid. Presnted article deals about the structure of various marketed as well as drugs under investigation containing β-lactam nucleus and  their pharmacological activities. The presented article is related wth the various β- lactam derivative with their various pharmacological activities.

  • TREATMENT OF MALARIA IN PAEDITRICS: A REVIEW
    28 January 2013
    TREATMENT OF MALARIA IN PAEDITRICS: A REVIEW

    About Author:
    Kambham Venkateswarlu
    Final Year Graduate Student
    Sri Lakshmi Narasimha College of Pharmacy,
    Palluru, Chottoor-517132, Andhra Pradesh, India.
    k.v.reddy9441701016@gmail.com

    ABSTRACT:
    Malaria is an infectious disease caused by a parasite (plasmodium) which is transmitted from human by the bite of infected female Anopheles mosquitoes. Four species of the parasite plasmodium are responsible for Malaria in humans: Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Plasmodium falciparum.
    This disease cause a nearly 300 to 400 million clinical episodes of malaria occur worldwide, out of which 1.5 to 2 million die every year. So this is also a most dangerous disease in children. This review reveals the treatment of malaria in paediatrics.

  • REVIEW ON ELECTROPHORESIS TECHNIQUES
    23 January 2013
    REVIEW ON ELECTROPHORESIS TECHNIQUES

    About Author:
    Kambham Venkateswarlu
    Final Year Graduate student
    Sri Lakshmi Narasimha College of Pharmacy,
    Palluru, Chittoor-517132, Andhra Pradesh, India
    k.v.reddy9441701016@gmail.com

    ABSTRACT:
    Electrophoresis is also called as cataphoresis. It is the motion of dispersed particles relative to a fluid under the influence of spatially uniform electric field. This electro kinetic phenomenon was observed for the first time in 1807 by Reuss (Moscow State University), who noticed that the application of a constant electric field caused clay particles dispersed in water to migrate. It is ultimately caused by the presence of a charged interface between the particle surface and the surrounding fluid. Electrophoresis is a rapid separation technique.Factors governing the migration of ions are Charge of ions, Size of the ions, Viscosity of the medium, Voltage applied, pH of buffer and ionic strength. Factors affecting electrophoresis are Molecular characteristics (size, shape), Buffer Properties, Electric Field Characteristics, Temperature.

  • A REVIEW ON MUSSAENDA SPECIES
    21 January 2013
    A REVIEW ON MUSSAENDA SPECIES

    About Authors:
    Bharathi.V*, SwarnaLatha.D, M.Sreenivasulu
    Annamcharya college of pharmacy, newboyana pally, rajampet(M),
    kadapa(dt). Andhara Pradesh, India.
    *bharu.v.net@gmail.com

    ABSTRACT:
    Medicinal plants have played an essential role in the development of human culture. Many of the modern medicines are produced indirectly from medicinal plants, for example aspirin. The present study was concentrated on past work reported on the some mussaenda species and study of different activities and phyto constitutions reported on mussaenda species. The genus Mussaenda (rubiaceae) is an important source of medicinal natural products, steroids, flavonoids, glycosides and only a few number of species reported positive for alkaloids and tannins. Many Mussaenda species were reported to possess anti-oxidant, anti-inflammatory in different models, analgesic, antimicrobial, diuretic, antiphlogistic and antipyretic, acute gastroenteritis and dysentery, anti- fertility activity, antiviral property , antibacterial effect rarely for hepato protective activity and wound healing activity.

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