Review Articles

About Author:
Richa Shrivastava
National Institute Of Pharmaceutical Education And Research
Niper, Guwahati
richashrivastava18888@gmail.com

Dementia is defined as a loss of intellectual abilities that is severe enough to interfere with social or occupational functioning.
Alzheimer’s disease (AD) is most common cause of dementia. 50-70% of all cases of dementia are due to Alzheimer’s disease.
AD is characterized by early memory deficits, followed by gradual erosion of other cognitive functions. The most severe neuropathological changes occur in the hippocampus, followed by association cortices or subcortical structures, including the amygdale and nucleus basalis of Meyhert.

ABOUT AUTHORS:
Madhuri D. Ghadage*¹, Gajanan H. Banapure^2
1Department of Pharmaceutics, SMBT College of Pharmacy, Dhamangaon, Nashik
²H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur Dhule
*maadhuri.ghadge@gmail.com

ABSTRACT
The controlled release of drugs in slow and sustained manner is one of the major challenges in drug delivery system. Targeting of drug to the particular site is an important aspect of drug delivery system. Carrier technology offers an intelligent approach for drug delivery by coupling the drug to a carrier particle such as microsphere which modulates the release and absorption characteristics of the drug. These delivery systems offer numerous advantages over the conventional dosage forms including improved efficacy, reduced toxicity, and improved patient compliance. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs. In future microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, genetic materials, targeted and effective drug delivery. The current aim of this review is to study various aspects of the microparticulates drug delivery system including method of formulation, evaluation & characterization.

ABOUT AUTHOR
Kunal Roy
NSHM Group of Institutions Knowledge campus,
Department of Pharmaceutical Analysis & Quality Assurance
Kolkata-700053
kunal.roy17@gmail.com

ABSTRACT:
Counterfeit Culture is a one of the most important and dangerous crime in the world of drugs and its related products  and  explores the dangerous and sometimes deadly world of fake, fraudulent, and faux products. The pharmaceutical  industry has a has history of peddled knock-off  dosage forms, medical devices   but during the last 15 years, it has mushroomed into a global phenomenon.
The range of counterfeit goods now being produced includes pharmaceuticals. The traffic in counterfeit goods is now estimated at a staggering $350 billion representing nearly 10% of all global trade. This illicit and highly profitable criminal enterprise continues to grow unabated and has been linked to organized crime syndicates around the world.

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ABOUT AUTHOR:
Kambham venkateswarlu
final year graduate student
Sri lakshmi narasimha college of pharmacy,
palluru, chittoor-517132, andhra pradesh.
k.v.reddy9441701016@gmail.com

ABSTRACT:
Mango (Mangifera indica L.) is the most popular fruit crop in the orient particularly in India, where it is considered as the best choice among all indigenous fruits. It occupies relatively the same position as that enjoyed by apple in temperate America or Europe. It ranks first among all the fruits of India in area and production.
Global production of mango is concentrated mainly in Asia and more precisely in India. Mango is grown in 85 countries, among which 63 countries produce more than 1000 metric tonnes in a year. In these countries, mango serves as an integral part in human life since it is not only a rich source of nutrients but also a common good shared in culture, life style and religion.