EPIDermizz, a skincare division of Nippon Seiyaku Pvt. Ltd. Nippon Seiyaku Pvt. Ltd. is an associate of Nippon Seiyaku co. Ltd., Japan which have been started its operation in Indian Market in 2001. Having robust brand NUTRIFACTS, Nippon is one of the most admired companies in pediatric fraternity. It has the history of pioneering in the area of nutrition by launching molecules like Methylcobalamine, Benfothiamine and Co Enzyme Q10 first time in India.

Virchow Biotech Private Limited (VBPL), an innovative biotechnology company headquartered at Hyderabad, India. VBPL also has offices located in the United States of America ( at Nashville, Tennessee)

Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia.

NIMS Institute of Pharmacy is approved by AICTE (All India Council for technical Education), Government of India. It offers undergraduate, postgraduate and Ph. D. programmes. The Institute has its separate building in the campus with spacious well equipped laboratories for each discipline and specialization. Pharma D. course has been designed on the lines of some universities in USA.

Bayer is a global enterprise with core competencies in the fields of health care, nutrition and high-tech materials. The company’s products and services are designed to benefit people and improve their quality of life.

Wockhardt today, is distinguished by a strong and growing presence in the world's leading markets, with more than 65% of its revenue oming from Europe and the United States. Wockhardt's market presence covers formulations, biopharmaceuticals, nutrition products, vaccines and active pharmaceutical ingredients (APIs).

About Authors:
KALPESH PATEL, JAYACHANDRAN E.*, SREENIVASA G.M.
* P.G. Department of Pharmaceutical Chemistry,
S.C.S. College of Pharmacy, Harapanahalli-583131,
Karanataka, India.
*drjc_2006@rediffmail.com, kalpesh.m.pharm@gmail.com

Abstract
Various substituted 3-amino-1-(2,4-dinitro phenyl)-5-[(5-substituted-1,3,4-oxadiazol-2-yl)amino]-1-H-pyrazole-4-carboxyamide and (5E)-5-[4-(dimethylamino) benzylidene]-3-(5-substituted-1,3,4-oxadiazol-2-yl)-2-phenyl-3,5-di hydro-4H-imidazol-4-one have been synthesised and evaluated for antiinflammatory activity. Structure of these products has been established by IR, ¹H NMR data. Significant activity were observed for some members of the series.

National Institute for Research in Reproductive Health (NIRRH), formerly known as Institute for Research in Reproduction is a premier research institute of the Indian Council of Medical Research (ICMR). It is situated in the vicinity of a number of hospitals and research institutes in central Mumbai.

Troikaa mainly focuses on Novel Drug Delivery Systems (NDDS). The company firmly believes in providing superior therapeutic benefits by improvising the formulations through Innovative Technologies.
Six patents have been filed in various areas of drug delivery. To handle competition, Troikaa adopted various multifaceted strategies to help stand their ground in the competitive market. Another fact that helps us stand out is their high quality products.

With USFDA approvable API facility - Mac-Chem has carved a niche for itself in the exceedingly competitive and quality-conscious sphere of pharmaceuticals manufacturing. The paradigm shift of leading Indian pharmaceutical companies to target low volume and blockbuster products for regulated markets has been the inspiration behind the launch.

About Authors:
S.Kameshwaran^1*, V.Suresh¹, M.Mohanraj^2
1Department of pharmacology,
JKK munirajah medical research foundation and College of Pharmacy,
B.Komarapalayam, Namakkal, Tamilnadu - 638183
²Marineboitoxinology labs, CAS in marine biology, Annamalai university,
Chidambaram, Tamilnadu-608502
*kamesh.pharm@gmail.com

ABSTRACT
Tecoma stans flowers have been traditionally used for many ailments including cancer. In the present study, anti cancer activity of methanolic flower extract of T.stans (METS) was evaluated using both in vitro and in vivo methods. METS was subjected to preliminary qualitative phytochemical investigations by using standard procedures. In vitro antitumor activity of METS was evaluated by the MTT assay methodusing Vero and HEP-2 cell lines. Then the extract subjected to in vivo anti cancer activity using Ehrlich ascites carcinoma (EAC) tumor model. The activity was assessed Increase in life span, average increase in body weight, changes in food intake, tumor volume, tumor weight, viable cell count, non viable cell count, PCV, Total cell count and hematological studies. The potency of the extract was compared with standard 5-flurouracil (20 mg/kg i.p.).In in vitro anti cancer activity METS exhibited significant cytotoxic activity against both cell lines even at different concentrations. Oral administration of METS at the dose of 200 and 400 mg/Kg, significantly (p < 0.001) increased the survival time, non viable cell count and decreased the average body weight and food intake, viable cell count of the tumor bearing mice. After 14 days of inoculation, METS was able to reverse the changes in the hematological parameters, protein and PCV consequent to tumor inoculation.The results indicate that METS possess significant antitumor activity on dose dependent manner.

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The foundation of Dr B. R. Ambedkar University (originally known as Agra University) was laid on the 1st of July, 1927, as a result of hectic efforts of a band of enthusiastic educationists like Rev. Canon A.W. Davis, Munshi Narain Prasad Asthana, Dr L.P. Mathur, Lala Dewan Chand, Rai Bahadur Anand Swaroop and Dr Brajendra Swaroop,.

Applications are invited for the position of Junior Research Fellow (JRF) in Department of Biotechnology (DBT) sponsored project “Targeting the mitochondria dependent and independent apoptotic signaling by Nanoparticulate drug conjugate to induce apoptosis in cancer cells”.

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