Applications are invited from Indian nationals for the following non-teaching posts on direct recruitment / deputation / contract basis in the Pay Band and Grade Pay indicated against each of the post plus usual allowance at Central Government rates.

Applications are hereby invited from eligible candidates for recruitment to various posts in different Departments under Government of NCT of Delhi and, its autonomous/local bodies. The details regarding name of the post(s), post code, Department, number of vacancies, educational qualifications, experience required, pay scale, age limit etc. as per the Recruitment Rules provided by the user department are given at Section A of this Advertisement.

Applications are invited for the posts of Professor, Associate Professor and Assistant Professor, which are being recruited on Regular basis in the School of Computational Sciences, Education, Social Sciences (Sub- Centre, Latur ), Social Sciences (University Campus), Technology (Sub-centre, Latur), Mathematical Sciences (Mathematics & Statistics), Physical Sciences, Life Sciences, Earth Sciences, Language & Literature [Marathi/English], Management (Sub-Centre, Latur), and Pharmacy of this University.

About Author:
Mr. RAJU A. MODHAVADIYA
School of Life Sciences
University of Hertfordshire, UK

Abstract:
The main concept of the study was to find out the penetration of boots ibuprofen gel at different frequencies such as 20 kHz and 40 kHz through cellulose membrane exposed to ultrasound. Different sonicator bath were used for different frequencies. Ultrasound has been used to enhance penetration of ibuprofen from transdermal preparation. Boots ibuprofen gel was used in the experiment. Ibuprofen is a NSAIDs drug which is used to enhance healing effect against inflammation, pain and analgesics.
Frequency, intensities, duty cycle are the important factor. In this experiment frequency variable was used. 20 kHz and 40 kHz frequencies were used in this experiment.Boots ibuprofen gel max (10%) was used to measure the penetration of ibuprofen through the cellulose membrane exposed to ultrasound. By using the Franz diffusion cell penetration of ibuprofen was found out. An amount of ibuprofen permeated through cellulose membrane was found out using High Performance Liquid Chromatography (HPLC).       Penetration of  ibuprofen was found out more lower frequency.  However the penetration ibuprofen also increase compare to control in first hour. The ANOVA result: sample assuming equal variances were performed to find out significance difference (P<0.05) between control and different ultrasound frequencies and also the rate gradients were measured. The P value got for the control and 40 kHz frequency was 0.123, which indicate that there is no significance difference observed for permeation of ibuprofen from gel . P value of control and 20 kHz frequency applying for 2 min was 0.05 which was similar P value, which shows that nearly significance observed between two value. The P value of control and 20 kHz for 5 minute was 0.002 which indicate that there was a significance observed between this two value.   From the result it shows that lower frequency with more time give good penetration result.

J. B. Chemicals & Pharmaceuticals Ltd. (JBCPL), known to many as Unique Pharmaceutical Laboratories is one of India's leading global pharmaceutical companies. The company manufactures and markets a wide range of pharmaceutical formulations.

Post: Manager Outsourcing

IICT invites applications from highly talented and research oriented candidates to join as Junior Research Fellow (JRF) to pursue PhD Program at IICT for the Academic Session starting from January 2012.  A brief profile of research activities at IICT is given in the Annexure enclosed.

The Institute has completed successful 25 years.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu.

About Author:Ratnadeep V. Ghadage.
Department of Pharmaceutical Chemistry,
Appasaheb Birnale College of Pharmacy, Sangli,
Maharashtra, India

ABSTRACT:
Any investigation in human subjects intended to discover or verify the clinical, pharmacological and/or other pharmacodynamic effects of an investigational product(s), and/or to identify any adverse reactions to an investigational product(s), and/or to study absorption, distribution, metabolism, and excretion of an investigational product(s) with the object of ascertaining its safety and/or efficacy. The terms clinical trial and clinical study are synonymous. Clinical trials examine the safety and efficacy of interventions, or treatments, in human subjects. This manuscript focuses on pharmaceutical clinical trials. The word subject is used deliberately here, since all participants in clinical trials are subjects, even if they are under the care of a personal physician, and therefore patients in that context, at the time of the trial. The pharmaceutical industry is now a more significant investor in clinical trials, but in addition to these opportunities, it is being challenged by the financial impact of managed care and medicaid regulations on academic medical-center revenues. Besides that, there is growing public concern about our systems for protection of human subjects, along with some conflicts. There are public expectations that clinical research will yield substantial advances in the health of the public. Once clinical research studies are completed and a drug has been approved for marketing by a regulatory agency, reports of the drug’s safety and efficacy will be published in the clinical literature. This dissemination of the results provides clinicians and research scientists with evidence of the beneficial administration of the drug.

About Authors:
PANKAJ MUSYUNI*, PROF. (Dr.) B.P. NAGORI¹, Mr. AKASH MIDHA²
*M. Pharm. (Pharma Management & Regulatory Affairs)
1 Director, Lachoo Memorial College of Science & Technology
2. Lecturer, Lachoo Memorial College of Science & Technology
Lachoo Memorial College of Science & Technology
‘Pharmacy Wing’, Jodhpur, Rajasthan
INDIA

ABSTRACT
Ethics can be explained as branch of philosophy related with the implication of all aspects of human behavior and nature. The purpose of this paper is to present an overview and relevance of business ethics in management and pharmaceutical industry scenario. The rationale of business can not be only illustrated by profit maximization but also by the social concern of the organization. This paper demonstrates the concept of business ethics with various attributes, factors and impact on society and also emphasize on code of ethics and its importance. Present paper also discusses common ethical problems within a pharmaceutical organization. A practical approach as case studies related to pharmaceutical industries will identify the issues and implications for ethical development, advancement and globalization of business ethics. Concept of paper focuses attention on the development of an attitude which should be adopted to understand various terms of ethics and development for social and business concern.

The growing Indian market for Schwabe products necessitated to establish a manufacturing facility in India with the aim to provide standard quality products at affordable Indian price. Schwabe remedies had a long tradition in India. Homoeopaths in India have used and continue to use Schwabe formulations based on their deep faith in the quality of its medicines. In fact our first order from India was raised over a century back.

About Author:
Vijay M. Waghulkar^1* (M.Pharm, D.B.M.), Dr. Supriya S. Deshpande² (M.Pharm, Ph.D), Pooja A. Kohle³  (M.Sc)
*Corresponding author
1. Lecturer, Dept of Quality Assurance
Vidyabharati, College of Pharmacy, Camp, Amravati – 444601,
Maharastra, India.

2.Professor and HOD
Punjabrao Memorial Medical College of Pharmacy,
Panchvati,  , Amravati – 444602,
Maharastra, India

3. Lecturer,Dept. Cosmectic Technology
Vidyabharati Mahavidyala, Camp, Amravati – 444601,
Maharastra, India.

Abstract
Diabetes mellitus is caused due to deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin producD.Diabetes mellitus often referred to as diabetes—is a condition in which the body either does not produce enough, or does not properly respond to, insulin, a hormoneproduced in the pancreas. Insulin enables cells to absorb glucose in order to turn it into energy. This causes glucose to accumulate in the blood, leading to various potential complications.

To overcome such complication Indian scientist have develop new techniques for diabetics i.e. single shot insulin which ,  is very essentials, blessful, create new ray of hope to the patients of diabetics ,give relief upto 120 days.

About Author:
Robby Kumar*, Amar Nagesh Kumar*
*Department of Biochemistry,
SSR Medical College, Mauritius

ABSTRACT
Genomics is the study of an organism's genome and the use of the genes. It deals with the systematic use of genome information, associated with other data, to provide answers in biology, medicine, and industry.

Genomics has the potential of offering new therapeutic methods for the treatment of some diseases, as well as new diagnostic methods. Other applications are in the food and agriculture sectors. The major tools and methods related to genomics are bioinformatics, genetic analysis, measurement of gene expression, and determination of gene function.

About Author:
D. J. Kalena^*, C. N. Patel
Department of Quality Assurance,
Shri Sarvajanik Pharmacy College,
Near arvind baug, Mehsana - 384 001, Gujarat, India

A simple, precise, accurate and rapid high performance thin layer chromatographic method has been developed and validated for the simultaneous estimation of atorvastatin calcium and olmesartan medoxomil in combined dosage forms. The stationary phase used was TLC aluminium plate precoated with silica gel 60F₂₅₄. The mobile phase used was a mixture of acetonitrile: chloroform: methanol: 10% glacial acetic acid (7: 2: 1.5: 0.1 v/v/v/v). The system was found to give compact spot for both atorvastatin and olmesartan (R_f value 0.5±0.01 and 0.76±0.02 respectively). The densitometric analysis of spot was carried out in reflectance mode at 253 nm. The method was validated in terms of linearity, specificity, precision, robustness and accuracy. The calibration curve was found to be linear in the range of 200 to 800 ng/spot for atorvastatin and 400 to 1600 ng/spot for olmesartan. The limit of detection and the limit of quantification for the atorvastatin were found to be 178.239 and 540.11 ng/spot and for olmesartan 40.10 and 121.51 ng/spot, respectively. The proposed method can be successfully used to determine the drug content of marketed tablet formulation.

About Author:
Sugumaran M., T. Vetrichelvan
Department of Pharmaceutical Chemistry,
Adhiparasakthi College of Pharmacy,
Melmaruvathur - 603 319, Tamilnadu , India

Abstract
High performance thin layer chromatographic finger print parameters had been developed for  Piper betle leaf oilisolated from karpoori, sirugamani and vellaikodi variety available in tamilnadu to fix standards. At shorter wavelength (254 nm) resolution was better for, so, this wavelength can be taken for obtaining optimum HPTLC finger printing for  volatile oil of this medicinal plant leaves. As per the data,   Karpoori variety of piper betle leaf oil  only showed  presence of  eugenol content. So, essential oil obtained from this variety should be included in the commercial tooth paste to get  antimicrobial activity against dental pathogens when compared to other studied variety.

NAARI aspires to be a world leader in the area of female healthcare, providing medical solutions from puberty to menopause. Our aim is to be the world’s first 100% integrated generic female health pharmaceutical company. This implies complete involvement in every step of production, going from plant extract to final dosage forms.

The Public Health Foundation of India (PHFI) is a public private partnership that has collaboratively evolved through consultations with multiple constituencies including Indian and international academia, state and central governments, multi & bi-lateral agencies and civil society groups. PHFI is a response to redress the limited institutional capacity in India for strengthening training, research and policy development in the area of Public Health.

NAARI aspires to be a world leader in the area of female healthcare, providing medical solutions from puberty to menopause. Our aim is to be the world’s first 100% integrated generic female health pharmaceutical company. This implies complete involvement in every step of production, going from plant extract to final dosage forms. By giving our stake holders cutting edge expertise, we set the standard for female health products, globally.

About Author:
Sharath Kumar Pallikonda*¹, Srikanth Subburu², Shanker Reddy Soma², Chandra Shekar Reddy^3
1,2Vathsalya College Of Pharmacy,
Bhongir, Dist: Andhra Pradesh, India - 508 116

Abstract
A simple, sensitive, rapid, robust and reproducible method for the determination of Quetiapine fumarate in bulk and pharmaceutical formulation (Tablets) was developed using reverse phase high performance liquid chromatographic method (RP-HPLC). The RP-HPLC analysis was performed isocratically on XTERRA C18 (4.6X150mm), analytical column using a mobile phase consisting of ortho phosphorus buffer and acetonitirle in the Ratio of 60:40v/v, with a flow rate of 0.6ml/min. The analyte was monitored with UV detector at 290nm. The developed method Quetiapine fumarate elutes at a run time of 10 min. The proposed method is having linearity in the concentration range from 40 to 80 μg/mL of Quetiapine fumarate. The present method was validated with respect to system suitability, linearity, precision, limit of detection (LOD) and limit of quantification (LOQ), accuracy (recovery), ruggedness, and robustness. The proposed method can be readily utilized for bulk drug and pharmaceutical formulations.