The Indian Agricultural Research Institute (IARI) is the country's premier national Institute for agricultural research, education and extension. It has served the cause of science and society with distinction through first rate research, generation of appropriate technologies and development of human resources. In fact, the Green Revolution was born in the fields of IARI and our graduates constitute the core of the quality human resource in India's agricultural research and education.

About Author: Vipul Kumar Tyagi (B.Pharm)
Shri Gopichand College Of Pharmacy,
Ahera (Baghpat)

Introduction
Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however hand tremors, dysphasia in case of geriatric patients, the underdeveloped muscular and nervous systems in young individuals and h case of uncooperative patients, the problem of swallowing is common phenomenon which leads to poor patient compliance. To overcome these drawbacks, mouth dissolving tablets (MDT) or orally disintegrating tablets; (ODT) has emerged as alternative oral dosage forms. These are novel types; of tablets that disintegrate/dissolve/ disperse in saliva within few seconds. A fast dissolving tablet was prepared by using various super disintegrants taken in different concentration (10%, 12%, and 14%) and one control batch is prepared without disintegrants designated as four different groups of formulations(F-1,F-2,F-3 and F-4) . Chemical incompatibility studies confirmed that there is no interaction between drug and excipients used in the formulations. All the batches are prepared by direct compression method. Effect of disintegrants on the disintegration behaviour was evaluated, and all the tablets were evaluated for hardness, friability, weight variation, water absorption ratio, dissolution, and assay.Direct compression method involves the incorporation of superdisintegrants in to the formulation. Direct compression does not require water or heat during formulation procedure and it is well suited for moisture and heat sensitive drugs. Fast dissolving tablets have so many advantages over liquid dosage form and conventional tablets. Fast dissolving tablet is suited for tablets which are undergoing first pass effect, and it is increase their bioavailability. A fast-dissolving drug delivery system, in most cases, is a tablet that dissolves or disintrigrants in the oral cavity without the need of water or chewing. Most fast-dissolving delivery system films must include substances to mask the taste of the active ingredient. This masked active ingredient is then swallowed by the patient’s saliva along with the soluble and insoluble excipients. These are also called melt-in-mouth tablets, repimelts, porous tablets, oro-dispersible, quick dissolving or rapid disintegrating tablets.

About Author: Rajesh Nuni
Department of Pharmaceutical Analysis,
Vels School of Pharmaceutical Sciences,
Vels University, Pallavaram,
Chennai, Tamilnadu, India

Abstract
A reverse phase HPLC method is developed for the determination of Sumatriptan and naproxen in pharmaceutical dosage forms. Chromatography was carried out on a C8 column [4.6 x 150mm, 3.5mm, Make: XTerra] using a mixture of potassiumdi hydrogen ortho phosphate buffer and acetonitrile (50:50 v/v) as the mobile phase at a flow rate of 0.7ml/min. Detection was carried out at 285 nm. The retention time of the drug Naproxen and sumatriptan was 2.24 minand 5.871 min. The method produced linear responses in the concentration range of 60 to 100μg/ml of Sumatriptan and naproxen. The LOD values for HPLC method for naproxen and sumatriptan were found to be 3.20 and 3.36 ng/ml. The LOQ for Naproxn and Sumatriptan were foud to be 9.86 and 9.90 ng/ml respectively. The method was found to be applicable for determination of the drug in tablets.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India.

Banaras Hindu University ranks among the first few in the country in the field of academic and research output. This university has two campuses, 3 institutes, 16 faculties, 140 departments, 4 advanced centers and 4 interdisciplinary schools.

Naprod’s vision is to become a world class player in oncology through excellence in innovation, discovery of new manufacturing processes / drug delivery mechanisms and consistently high quality of production. We commenced operations in 1994 with the inauguration of our ultra-modern facility for the production of generics and formulations for oncology and other therapeutic applications. We are one of the pioneers in India in lyophilization.

About Author: Main author: Amar Nagesh Kumar,
Lecturer, Department of Biochemistry,
SSR Medical College, Belle Rive, Mauritius
Co-author: Robby Kumar,
Lecturer, Department of Biochemistry,
SSR Medical College, Belle Rive, Mauritius

Abstract
Objective: To correlate serum magnesium levels among pregnant women with increasing parity and comparison of magnesium levels in rural and urban areas of Guntur district, Andhra Pradesh, India.

Materials and Methods: A total of 100 pregnant women with pregnancy duration of 24 weeks and more were enrolled for the study. Blood from the antecubital vein was drawn and serum magnesium levels were estimated by the colorimetric method.

Results: In all, 48% of the pregnant women had serum levels less than the normal level (1.80 mg/dl). There was a significant decrease in serum magnesium levels with the increase in parity. But no significant decrease of magnesium level in serum was found when compared among rural and urban pregnant women.

Technical education in India contributes a major share to the overall education system and plays a vital role in the social and economic development of our nation.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India.

Indian Institute of Integrative Medicine (IIIM) is a national Institute of the Council of Scientific & Industrial Research (CSIR) of India, with primary focus of research on drug discovery from natural products (medicinal plants and microbial species). IIIM is a multi-disciplinary organization encompassing the natural products chemistry, medicinal chemistry, pharmacology, microbiology, biotechnology and botanical sciences.

The Tata Memorial Centre (TMC) is an autonomous Grant-in-aid Institution of the Department of Atomic Energy. The TMC is comprised of the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) and the Tata Memorial Hospital (TMH). The TMC conducts Ph.D. program in Life Sciences and is affiliated to the Homi Bhabha National Institute (Deemed University).

CLINOVEX – Clinical Research Solutions located in cochin, India is a premier Research & Training institute in clinical & biomedical sciences providing high quality, innovative approach to both Research & Training.

ESKAG, A 100 Crores Group with its presence in pharmaceutical, health care & bulk drugs having manufacturing units at west bengal and uttarakhand, now in hormonal therapy with its speciality division - REWEL invites applications to work in districts of West Bengal and Kolkata city..

Post: General Manager, Business development executive

ABBOTT HEALTHCARE PVT. LTD. is one of India's leading pharmaceutical companies with a strong presence  in 13 therapeutic segments with some of the most trusted brands like Phensedyl, Haemaccel, Stemetil, Tixylix, Supradyn & Phenergan in our portfolio. We also nave successful new products in acute and chronic therapies with brands like RockBon, Cefchamp, Cinaxon, CAAT, PPG, Nupod. Amongst the fastest grovwig companies in India. Abbott Healthcare Pvt.

About Author: Mr. Mahesh W. Thube*, Dr. Sadhana R.Shahi, Mr. Abhay Padalkar
Mr. Mahesh W. Thube*: Department of Pharmaceutics,
Government College of Pharmacy, Aurangabad - 431 005, Maharashtra, India
Dr. Sadhana R. Shahi: Assisstant Professor, Govt. College of Pharmacy, Aurangabad, Department of Pharmaceutics.

Abstract
Ion exchange resin (IER) is high molecular weight polyelectrolyte having charged functional site. IER are chemically vinyl, divinyl benzene and polystyrene copolymers. IER in past years have received extensive attention by pharmaceutical industry due to their versatile application. Previously IER were mainly used for water purification only but recently they have been studied for Novel Drug Delivery System. IER are mainly used for taste masking but, they also possess modifying release properties. The IER are complexed with drug to form resinates by batch process or column process. If necessary the resinates are coated with polymeric material by microencapsulation technique. Coated resinates acts as a controllable rate limiting factor for exchange of ions and also for exchange of drug, thus, modifying the release of drugs. The review article highlights the application of sustained and controlled release resinate for the development of various drug delivery system.