About Authors:
G.Amrutha
Microbiologist  in  Department  Of Microbiology
Institute Of Health Systems (HIS),  Hyderabad.
Osmania University

Abstract
Transplantation is the process of  removal of  damaged tissue or organ and replacing with new well functioning tissue or organ of same or different individual. The groundwork for the new science of transplantation immunology was laid by Medawar and other British biologists in the 1940s. They showed that rejection of tissue transferred from one person or animal to another was invariable, except for grafts between identical twins or a few special cases (e.g. cornea). In the 1950s they further showed that this tissue rejection was a response of the immune system. Other scientists who worked for transplantation are  Karl Landsteiner, Dr. Eduard Zirm, Dr. Alexis Carrel, Peter Gorer, Little and Tyzzer, George Snell, Dr. Joseph Murray etc..,Different types of organs like heart,skin,kidney,liver,cornea etc.., can be transplanted. Antigens which cause strong immune response and are most important in rejection of organs and tissues are called MHC antigens which play main role in transplantation. There are mainly 4 types of grafts. They are Autograft,Isograft,Allograft and Xenograft. The rejection may be acute and chronic and the mechanism of graft rejection is of mainly 2 types. They are sensitization stage and effector stage. Finally, the graft survival can be done by mitotic inhibitors, immune suppressive therapy etc..,

About Authors: 
Neha batra, honey jain
School of pharmaceutical science,
Jaipur National University, 
Jaipur

ABSTRACT
Herbal and natural products of folk medicine have been used for centuries in every culture throughout the world.Embelia ribes burm f. also known as Vidanga is one of the oldest herbs in Indian traditional medicine.This species is reported to be vulnerable in the Western Ghats of Tamil Nadu and Karnataka states of India and at a lower risk in Kerala state of peninsular India. Embelia ribes traditionally used as appetizer, carminative, laxative,  Anthelmintic  and  in liver diseases. Embelin as main consistuents of Embelia ribes having medicinal and pharmacological properties. The plant also  contains quercitol and fatty ingredients; an alkaloid christembine, a resinoid, tannins and minute quantities of a volatile oil. Embelia ribes posses many pharmacological action like analgesic, anti-fertility, antioxidant, antiandrogenic  and many more.

ANSWERS of Previous PharmaQUIZ-5:

1.A   2.D   3.A   4.A   5.B

6.A   7.C   8.B   9.D   10.D

Anglo French Drugs & Industries is a dynamic, rapidly expanding pharmaceutical company with established capabilities in the development of therapeutic formulations, marketing & sales, distribution and contract manufacturing.

J.B. Chemicals & Pharmaceuticals Ltd. is a fast growing Indian Pharmaceutical Company with a turnover of more than 850 crores. The company has excellent products like Nicardia, Metrogyl and Rantac. The company intends to expand its domestic presence by mass expansions in Mumbai for its Unique Division (Main Division).

Meyer, an associate of London based multinational Vitabiotics Ltd.,is a rapidly growing Pharma Co. in India. Leading pharmaceutical manufacturer, founded in 1982 .,in technical collaboration with OMEGA-MEYER Ltd Jersey( Br. Isles). H.O. based in THANE

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About Authors:
Hardwari L. Yadav, P.K. Singour, R.S. Pawar, U. K. Patil
Department of Pharmaceutical Chemistry,
VNS Institute of Pharmacy,
Neelbud, Bhopal (M.P.)

Abstract
Chalcone are the important constituent of many natural sources and have variety of biological activities. The novel chalcone derivatives isolated from the fruits of Mallotus philippinensis called mallotophilippens. The chalcones are synthesize by claisen-schmidt base catalyzed condensation of appropriate aromatic ketones or substituted aromatic ketones with benzaldehyde or substituted benzaldehydes. Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants, and have also been shown to display a diverse array of pharmacological activities. Recent reports suggest antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.

About Author: Ashish Kumar Verma¹, D.Raj. Anand¹, Garima A. Tewari²
1.    Jubilant Chemsys Limited Noida 201301
2.    Babu Banarsi Das University Lucknow

ABSTRACT
Aceclofenac and paracetamol in combination are available as tablet dosage forms in the ratio of 1:5. A simple, reproducible and efficient method for the simultaneous determination of aceclofenac and paracetamol in synthetic mixture was developed. The proposed method is based on the Q-analysis UV Spectrophotometric method. The absorbance maxima of aceclofenac and paracetamol were found to be 275.4 nm and 248 nm, respectively in methanol. In Q-analysis, the isoabsorptive point for both the drugs was found at 266.1 nm. The linearity range lies between 1-35 µg/ml for aceclofenac and 1-15 µg/ml for paracetamol at their respective wavelengths. Both the drugs obey Beer’s law. The recovery studies confirmed the accuracy of the proposed methods.

Lupin Pharmaceuticals, Inc. is the U.S. wholly owned subsidiary of Lupin Limited, which is among the top six pharmaceutical companies in India. Through our sales and marketing headquarters in Baltimore, MD, Lupin Pharmaceuticals, Inc. is dedicated to delivering high-quality, branded and generic medications trusted by healthcare professionals and patients across geographies.

ANSWERS of Previous PharmaQUIZ-4:
1.B   2.B   3.A   4.A   5.C
6.D   7.A   8.C   9.C   10.A
SEE QUESTIONS OF QUIZ - 4

Piramal Healthcare Ltd, a Piramal Group company, is a globally integrated healthcare company that fulfills unmet medical needs across the world. It has a growth track record of above 29% CAGR since 1988. Piramal Healthcare had consolidated revenues of US$ 656 million in FY2009. PHL is currently ranked 4th in the Indian market with a diverse product portfolio spanning several therapeutic areas.

Study Subject(s): Subjects taught at University
Course Level: Undergraduate and Graduate
Scholarship Provider:  ETS
Scholarship can be taken at: US, UK, Canada, Australia and other countries

ANSWERS of Previous PharmaQUIZ-3:

CavinKare- a youthful company fired by ideas, dynamism and professionalism first entered the hair care arena in 1990. The success story began with Chik shampoo, the name which rewrote every rule in the market by popularizing the sachet concept in India.
In this short span of time, CavinKare has not merely taken on the mighty MNC challenge but notched up a stupendous 46% compounded annual growth along the way.

North-Eastern Hill University was set up by an Act of Parliament and notified on 19th July 1973.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

The R&D Division of the company is engaged in herbal drug standardization and evaluation using newer and advanced methods available for standardization of herbal drugs like fluorescence quenching, combination of chromatographic and spectrophotometric methods, biological assays, use of biomarkers in fingerprinting. Immediate requirement to addressed the needs of patented Ayurvedic formulations, Herbal Supplements, Organic Herbs, Pure Herbs, Classical Ayurvedic Products.

About Authors:Kamal Sachdeva*², Preeti Garg¹, Manmohan Singhal², Birendra Srivastava²
1. School of Pharmacy, Suresh Gyan vihar University, Jaipur
2. School of Pharmaceutical sciences,
Jaipur National University,
Jaipur, India

Abstract: The extracts of the stem bark of Jatropha curcas (Family-Euphorbiaceae) were tested for anti-diabetic activity, using blood glucose level in normal fasted rats, glucose tolerance test. Methanol: acetone: water (70:20:10) crude extract of Jatropha curcas at the dose of 100 and 300 mg/kg had shown significant protection and lowered the blood glucose levels to normal in glucose tolerance test. The extract showed a significant anti- diabetic activity comparable with that of glibenclamide. These results indicate that the Jatropha curcas stem bark possess significant anti – diabetic activity.