• PharmaTutor
    31 October 2011

    SHORT INFORMATIVE REVIEW ON SINGLE SHOT INSULIN FOR DIABETICS

    About Author:
    Vijay M. Waghulkar1* (M.Pharm, D.B.M.), Dr. Supriya S. Deshpande2 (M.Pharm, Ph.D), Pooja A. Kohle3  (M.Sc)
    *Corresponding author
    1. Lecturer, Dept of Quality Assurance
    Vidyabharati, College of Pharmacy, Camp, Amravati – 444601,
    Maharastra, India.

    2.Professor and HOD
    Punjabrao Memorial Medical College of Pharmacy,
    Panchvati,  , Amravati – 444602,
    Maharastra, India

    3. Lecturer,Dept. Cosmectic Technology
    Vidyabharati Mahavidyala, Camp, Amravati – 444601,
    Maharastra, India.

    Abstract
    Diabetes mellitus is caused due to deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin producD.Diabetes mellitus often referred to as diabetes—is a condition in which the body either does not produce enough, or does not properly respond to, insulin, a hormoneproduced in the pancreas. Insulin enables cells to absorb glucose in order to turn it into energy. This causes glucose to accumulate in the blood, leading to various potential complications.

    To overcome such complication Indian scientist have develop new techniques for diabetics i.e. single shot insulin which ,  is very essentials, blessful, create new ray of hope to the patients of diabetics ,give relief upto 120 days.

  • Exploring Biological Activities of Quinoxaline Derivatives
    26 October 2011
    Exploring Biological Activities of Quinoxaline Derivatives

    About Author: *Ghadage Ratnadeep V., Shah Vishal V., Bapat Bhushan A., Shirote Pramod J.
    Department of Pharmaceutical Chemistry,
    Appasaheb Birnale College of Pharmacy,
    South Shivaji Nagar, Sangli, Maharashtra, India - 416 416

    Abstract:
    Quinoxaline and its derivatives are an important class of benzoheterocycles displaying a broad spectrum of biological activities which have made them privileged structures in pharmacologically active compounds.Quinoxaline also called benzopyrazine it has been considered as a wonder nucleus which posses almost all types of biological activities. This diversity in the biological response profile has attracted the attention of many researchers to explore this skeleton to its multiple potential against several activities. They are clinically effective as antibacterial, antifungal, anti-inflammatory, anticancer, anti-tubercular and antineoplastic agents. Interestingly, it also shows anti-HIV and anti-proliferative activity. Modification in their structure has offered a high degree of diversity that has proven useful for the development of new therapeutic agents having improved potency and lesser toxicity. Considering the extensive research on quinoxaline in the past, it was essential to review the wide spectrum of biological activity of quinoxalines. To conclude, this review will be beneficial for new drug discovery of quinoxaline moiety. Present article is sincere attempt to review wide range of biological activities of quinoxline moiety  given by researcher.

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