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A PROSPECTIVE AND COMPARATIVE STUDY ON THE EFFICACY OF THE ESCITALOPRAM AND CITALOPRAM IN MAJOR DEPRESSIVE DISORDER PATIENTS

About Authors:
*Anton Vinoth.T , Prof .K. Nagarajan , Mr. Manikandan
Department of Pharmacy practice, K.M College of Pharmacy,
Madurai, Tamilnadu
*vinoth.anton@gmail.com

ABSTRACT:
Mood disorders (affective disorders) are among the most common mental disorders encountered in clinical practice and divided into bipolar disorders and depressive disorders. The essential feature of these disorders is a major disturbance in mood. Depression is common, affecting about 121 million people world wide. At its worst depression can lead to suicide, a tragic fatality associated with the loss of about 85000 lives every year. By the year 2020, depression is projected to reach the second Major depression is among the most common mental disorders encountered in clinical practice. The problems associated with depression can become chronic or recurrent and lead to substantial impairment in an individual’s ability to take care of his or her everyday responsibilities. At its worst depression can lead to suicide, a tragic fatality associated with the loss of a large number of lives every year. Depression is the leading cause of disability as measured by YLDs and the leading contributor to the global burden of diseases (DALYs) in 2000.

The present study is done as it is the role of a clinical pharmacist to evaluate the efficacy and safety of the drugs acting through specific antidepressant mechanisms and to assess the possibility of matching patient symptom profile with antidepressant mechanism to achieve more rapid response or greater efficacy.

The aim of the study is tocompare the efficacy of Citalopram and Escitalopram in the Major Depressive Disorder Patients during the first 8 weeks (acute phase) of treatment.

Government invites applications from Fresh & Exprience B.Pharm, M.Pharm in CGMSC - 59 posts | Store officer, Assistant Manager (Drug Store Dept.), QC Officer, Deputy Manager - Q.C & more

CGMSC limited, is regulated by CG government, which buy or otherwise acquire all and surgical dressings, kits and instruments and to sell or supply to various hospitals and other health centers and to the General Public. Online applications are invited for filling up positions at CGMSC from 10/09/2012 to 10/10/2012, evening 5.00

Osmania University invites Project Associate, Technical Assistant - 3 Posts

Osmania University, established in 1918, is the seventh oldest in India, the third oldest in south India and the first to be established in the erstwhile princely state of Hyderabad. Throughout its existence of over eight decades, it has shown remarkable progress and sustained an integrated development of all faculties. It has significantly contributed to the academic and economic development of not only the region but also of the Country.

Urgently looking for suitable candidate for B.Pharm, M.Pharm, M.Sc for IPR position for R&D dept in API industry - 2 posts

API PLANT AT BARODA

Post: IPR officer - 2 posts

Advertisement inviting applications for PhD programme at IIT Ropar

Application are invited for the post of JRF/Project Fellow in Pondicherry University - 2 posts

Pondi cherry is a Union Territory with one of the highest levels of quality of life in the country with excellent physical infrastructure and almost a hundred per cent literacy level. It is also the place where Sri Aurobindo and the Mother chose to stay and their writings remain a tremendous source of spiritual awakening that emphasizes the progress of humanity and its spiritual brotherhood.

Applications Inviting from M.Pharm, PhD, Post Doc Candidates to work as Writers, Authors, Co-Authors, Editors for contributing Articles and Chapters to various Pharmacy books - 100 Posts.

Working towards the preparation of articles and pharmacy books (B.Pharm, M.Pharma, Pre-PhD) as per the AICTE syllabus and in search of hard working M.Pharm/Ph.D/Post Doc candidates from all across the country, having great zeal for writing and contributing various chapters for these books as per their interest.

Work as Pharmacists and Senior Pharmacists in Hospital by Clini India- 20 Posts - Freshers

Clini India, a premier Training institute in CR located in the Heart of the City at Somajiguda, Hyderabad for close to 4 years has been providing ethical and high quality Clinical Research Education. Presence of our Campuses in across major cities makes us an unrivaled Pan India Institute to impart CR education par excellence.

ESIC invites for ENGAGEMENT OF RETIRED PARAMEDICAL STAFF

Gujarat Technological University invites Project Officer (IPR / Patents) | Government job

The Gujarat Technological University was established vide Gujarat Act No. 20 of 2007. The main objective of the University apart from other is to develop the knowledge of science, engineering, technology, management and environment for the advancement of quality of life of the mankind in general and in relation to the domain of engineering and technological development and applications.

Job as Area Manager in Colgate Palmolive India

A REVIEW ON ALZHEIMER’S DISEASE WITH THEIR NEUROLOGICAL PATHWAYS PATHOPHYSIOLOGIC MECHANISMS & DRUG TREATMENT ON THEIR TARGET SITE

About Authors:
Ajay Kumar*1, Dr. Bharat Prashar2, Robin Sharma1
1M. Pharm (Pharmacology)
2Head of Pharmacy Department
Manav Bharti University, Solan.
*ajaykumarsharma423@hotmail.com

ABSTRACT
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, primarily manifesting as a loss of memory in old aged people. In this disease the destruction of neurons in the cortex and limbic structures of the CNS occurs, particularly in basal forebrain, amygdala, hippocampus, cerebral cortex.  These areas are associated with functions of higher learning, memory, reasoning, behaviour, identification, an emotional control in brain. Alzheimer's disease is a devastating disease whose recent increase in incidence rates has broad implications for rising health care costs. Clinically, patients initially present with short-term memory loss, subsequently followed by executive dysfunction, confusion, agitation, and behavioural disturbances. This review comprises aspects of the introduction, history, types, etiology, pathophysiologic mechanisms of neurological pathways of Alzheimer’s disease and the drug treatments and their target site.

Opening for Regional Training Manager in Merck

Merck Limited (formerly E. Merck Limited) was set up in India as the first Merck subsidiary in Asia in 1967. The Company operates both its Pharmaceuticals and Chemicals businesses in the country.

Application are invited from Consultant in Department of AYUSH

Applications are invited from retired government officials with experience in Admn/Establishment matters as also working/retired AYUSH doctors/experts to serve as Senior Consultant/ Consultant/ Junior Consultant in this Department, on a consolidated remuneration. The appointment will be purely on contractual basis for a period of 12 months initially.

Eligible candidates are invited to Junior Research Fellow in National Institute of Nutrition (NIN) | Walk in - 2 posts

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu.

Job as Trainee in Spices Board- Walk in interview

Spices Board (Ministry of Commerce, Government of India) is the flagship organization for the development and worldwide promotion of Indian spices. The Board is an international link between the Indian exporters and the importers abroad. The Board has been spearheading activities for excellence of Indian spices, involving every segment of the industry. The Board has made quality and hygiene the corner stones for its development and promotional strategies.

NOVEL DRUG DELIVERY- AN INTELLIGENT DRUG DELIVERY FOR FUTURE

About Authors:
Swathi sree Karumuri*, Venkata Naveen Kasagana
Department of Pharmaceutics,
Sankaralingam Bhuvaneswari College of Pharmacy, Anaikuttam,
Sivakasi - 626 130, Tamilnadu, India
*swathi.karumuri2011@gmail.com

Abstract:
New drugs pursuing novel delivery technologies with the objective of improving drug safety, efficacy and site Targeting in a cost effective way has been a challenging area of work for researchers. Their eminent work in the field of Novel technology has introduced many drug delivery methods to fulfil the requirements of pharmaceutical manufacturers and customers. Multiunit particulate systems (MUPS) are novel MDDS techniques that have gained importance, not only because of their ability to control drug release, but also for the modified drug-release profiles they facilitate. Similarly Acoustic targeted drug delivery (ATDD) is a method that uses ultrasound energy to enhance the transport of molecules into and/or across specific tissues. P.L.E.A.S.E. (Painless Laser Epidermal System) is a transdermal delivery device that uses a special laser source to create micro pores in the skin through which high molecular weight drugs are delivered painlessly in a highly controlled and accurate fashion. Oral delivery of insulin with increased lipophilicity across the gastrointestinal epithelium by the application of Eligen technology. Development of nanorobots with biosensors for medical target identification and drug delivery plays a prominent role in the diagnosis and treatment of Diseases. Gene delivery technology that turn off or on gene responsible for causing diseases like cancer and diabetes. The present article describes how Novel Drug delivery fulfils the Patient Needs on a Global Level and forms a key technology in the field of pharmaceuticals.

NOVEL DRUG DELIVERY TECHNOLOGY- ADAPTIVE NEXT GENERATION TECHNOLOGY

About Authors:
Venkata Naveen Kasagana*, Swathi sree Karumuri
Department of Pharmaceutics
Sankaralingam Bhuvaneswari College of Pharmacy, Anaikuttam,
Sivakasi - 626 130, Tamilnadu, India.
*naveen.kasagana@gmail.com

Abstract:
In the recent past global pharmaceutical markets has involved in developing the new Novel and Advanced drug delivery systems in a safe & cost effective manner. This resulted in the introduction of a variety of Controlled and Targeted drug delivery methods with ease of administration and patient compliance. The transition that took place by the introduction of nano technology in the field of pharmacy leads to the development of many intelligent drug delivery systems like Nano Beacon and Mini Beacons, Trojan horse Nano particles, MEMS & NEMS (Micro and Nano Electromechanical Systems). Cochleate delivery vehicles “A novel lipid-based system” represent a unique technology platform for oral and systemic delivery of drugs. BEMA (Bio Erodible Muco Adhesive Disc) drug delivery technology for prolonged acting action has contribution to the novel approach. Also a much awaited Non-injected insulin formulation “Nasal Insulin spray”, as a vaccine and also in the treatment of Type-II diabetes, provided a shift in the development of drug delivery systems. Duocap (Capsule-in-a-capsule), Electro capsule, Light up delivery monitoring technology (LDMT) are some of the controlled & targeted oral drug delivery systems, which provides a new way of formulating poorly soluble compounds and monitor the release rate of the drug. Apart from briefly describing the above technologies, the article includes the upcoming system of using Air as a barrier for Controlled release and application of medical devices as drug and their contribution to the World of pharmacy.

Walk in interview for the post of Pharmacist in NATIONAL RURAL HEALTH MISSION DISTRICT HEALTH SOCIETY

The Vice-Chair Person on behalf of District Health Society, Daman at Directorate of Medical & Health Services, Community Health Centre, Moti Daman is conducting a walk in interview for the posts of Paramedical staffs purely on short term contract basis.

Post: Pharmacist

Ph.D. programmes of the AcSIR for Pharmacy & others

India's ability to acquire a leadership position in the world, in the economic, demographic and intellectual fronts, would greatly depend on her ability to consolidate and take a vantage position in science & technology. Highly skilled S&T personnel adequately trained to face the challenges of inter-disciplinary and trans- disciplinary transformation of the biological and engineering sciences will command the workspace of tomorrow.

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