Covidien and Medtronic are committed to improving the lives of patients through ground-breaking medical technologies. By bringing our companies together, we are able to expedite our ability to create the meaningful innovations and therapies that fuel our mission to improve patients’ lives. This partnership will create new opportunities for skilled, ambitious people to change the way we work, and ultimately deliver better health for more people.

Post : Regional Sales Manager/ District Manager, Reg/Ctry

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ABOUT AUTHOR
Dhrubo Jyoti Sen
Department of Pharmaceutical Chemistry,
Shri Sarvajanik Pharmacy College,
Mehsana, Gujarat, India
dhrubosen69@yahoo.com

ABSTRACT: Our goal is to perform in-vitro biotransformation of Prodrugs of ibuprofen+paracetamol, diclofenac sodium+paracetamol and ibuprofen+diclofenac sodium by acidic and alkaline hydrolysis of both ester (–COO–) and amide (–CONH–) linkages into free drugs and chromatographically separation of their Rt in HPLC. Since both ester (–COO–) and amide (–CONH–) linkages are susceptible for hydrolysis in both acidic pH (gastric pH) and basic pH (intestinal pH) to produce parent drug ibuprofen, diclofenac and paracetamol by biotransformation in in-vivo; so it will be implemented as a Prodrug which can show prolong action on pain and fever after getting release into free parent drug by biotransformation. The HPLC (High Performance Liquid Chromatography) study reports the retention time (Rt) and release kinetics of three Prodrugs by taking HPLC degradation datas of three samples of Prodrugs and individual HPLC datas of parent drugs separately to compare the Rt value of release of three drugs from Prodrugs in both acidic and alkaline pH. Prodrug–A (logP=4.56) releases Ibuprofen & Paracetamol, Prodrug–B (logP=4.90) releases Diclofenac & Paracetamol and Prodrug–C (logP=6.13) releases Ibuprofen & Diclofenac. This is a comparison study of drug release in in-vitro gastric as well as intestinal pH focusing on in-vivo biotransformation.  Keywords: Prodrug-A/Prodrug-B/Prodrug-C, Ibuprofen, Paracetamol, Diclofenac sodium, Molecular weight, logP, UV λmax, IR, Mobile phase, TLC-Rf value, HPLC-Rt value, LOD, LOC

We want you to understand the medicines that you take and that you give your loved ones. Buying medicines may require you to try 5 medical stores which are miles apart. We want you to be able to do it with a click. Medicines can be expensive. We want you to know about medicines which have the same composition as prescribed by your doctor but can be considerably cheaper. We want you to be in charge of your medical care.

Post: Pharmacist / Sr. Pharmacist (10 posts)

The Guru Jambheshwar University of Science & Technology, Hisar, was established on October 20,1995 by an Act of the Legislature of the State of Haryana with the objectives 'to facilitate and promote studies and research in emerging areas of higher education with focus on new frontiers of technology, pharmacy, environmental studies, non-conventional energy sources and management studies and also to achieve excellence in these and connected fields'. It was formally inaugurated on November 1, 1995. It is named after Guru Jambheshwar Ji Maharaj, a saint environmentalist of 15th century. Keeping in view the nature of courses offered at the university and the mandate for which it had been established the name of the university has been changed as Guru Jambheshwar university of Science & Technology.

Post : Junior Research Fellows (06 posts)

Dr. Homi Jehangir Bhabha conceived the Nuclear Program in India. Dr Bhabha established the Tata Institute of Fundamental Research (TIFR) for carrying out nuclear science research in 1945. To intensify the effort to exploit nuclear energy for the benefit of the nation, Dr Bhabha established the Atomic Energy Establishment, Trombay (AEET) in January 1954 for multidisciplinary research program essential for the ambitious nuclear program of India. After the sad demise of Bhabha in 1966, AEET was renamed Bhabha Atomic Research Centre (BARC).

Incorporated in the year 1994, Syngene International is one of India"s premier contract research and manufacturing organizations in providing customized service. Our services encompasses all across discovery chain: early stage discovery, process development, cGMP manufacturing and formulation development both in the small molecule and novel biologics area. Based in Bangalore, Karnataka, the Company is situated in a 90 acre Special Economic Zone with over 100000 sq. mt of built up facilities.

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ABOUT AUTHORS
L Reddenna¹*, Dr. P. Venkatesh¹, K Siva Kumar², A Sai keshava Reddy²
1* Department of Pharmacy Practice,
Jagan’s College of Pharmacy,
Nellore, Andhra Pradesh, India
² Department of Pharmacy Practice,
Nirmala College of Pharmacy, Kadapa, Andhra Pradesh, India
*reddennapharmd@gmail.com

ABSTRACT
The subsistence of a human H/h genetic polymorphism was first recognized by the innovation of an individual devoid of the H antigen on red cells in Bombay who had antibodies in plasma reacting with all the red cells exhibiting the normal red cell ABO phenotypes. These persons were genetically termed as homozygous hh or Bombay phenotype. H-deficient Bombay phenotype is exceptional, since it occurs in about 1 in 10,000 individuals in India and 1 per 1,000,000 individuals in Europe. After the first report of Oh phenotype from Mumbai in 1952 by Bhende, numerous other workers detected this weird phenotype in India. The complexity with the Bombay phenotype is that the individuals having blood group of Bombay phenotype (Oh) can either receive autologous donation or blood from an individual of Bombay phenotype only; no other blood will match in case of an emergency blood transfusion. The aim of present study was to communicate the information about rare blood entity and to review the previous case reports.

The institute Ravishakar College of Pharmacy (RCOP), established in the year 2003 by Sarkar Mansarover Education Society, Bhopal which is a self financed society dedicated to the cause education by providing quality and affordable education to all classes of the society since last decade. RCOP is affiliated to Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (MP) and is approved by AICTE and PCI New Delhi. It offers B. Pharm. and M. Pharm. (Pharmaceutics, Pharmaceutical Chemistry and Pharmacology). The college is well equipped with state of art laboratories, computer room, classrooms, animal house and digital library to creating highly professionalism with excellencies, conceptual and innovative abilities in students by which the students abreast of current demands of pharmaceutical industry.

Post : Project Fellow/Junior Research Fellow (JRF)

Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.
We offer stimulating work environment & a career that spells growth. In tune with our plans, we require young, aggressive, dynamic, high performing and result oriented professional.

Post : Executive/Senior Executive– DSP

Roche Diagnostics India, with a sales turnover of INR 150 crores, nurtures an open, flexible and challenging work environment, which allows for rapid career progression. Favored by its geographic location in the heart of Europe, the Basel area is one of the most dynamic economic regions in Switzerland — a great place to live and work.

Post : Director - Oncology

Quintiles is the world’s largest provider of biopharmaceutical development and commercial outsourcing services. We bring a fully integrated approach to build biopharma and life sciences solutions – from pipeline through portfolio to population health. A career with Quintiles connects you to great opportunity to achieve professional success and impact healthcare around the world.

Post : Senior Clinical Process Specialist

CEPS established under the aegis of GGSIP University is engaged in research in Pharmaceutical Chemistry/Pharmacology/Microbiology & Bioethics. CEPS is looking for meritorious young researchers for pursuing research in the area of Pharmaceutical Chemistry, Detection, Isolation, Structural Elucidation & Biological Screening.

POST : Junior Research Fellow - 01 post, Research Associate - 01 post

Gland Institute of Pharmaceutical Sciences which was established in 2009 sponsored by Gland Pharma Ltd. One of the Leading Pharmaceutical company. The college was founded and governed by PVN Raju Educational Society.

Post: Associate Professors and Assistant professors

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Girijananda Chowdhury Institute of Pharmaceutical Science (GIPS) was established in the year 2007 as the first non-government Pharmacy institute in the state of Assam under the aegis of Shrimanta Shankar Academy (SSA). The institution is affiliated to, Assam Science and Technology University, Assam, approved by All India Council of Technical Education (AICTE), New Delhi and recognized by Pharmacy Council of India (PCI). The B.Pharm programme is accredited by National Board of Accreditation (NBA).  The College is constantly seeking to upgrade the quality of its education and actively participates in research to remain on the cutting edge.

Post :Assistant professor (Pharmaceutical Chemistry or Pharmaceutical Analysis)

The St. John's Research Institute (SJRI) is a part of the St John's National Academy of Health Sciences, which is run by the CBCI Society for Medical Education. From its inception, St. John's has set before it an ideal of excellence in academic courses as well as service to society as a result of which it has truly become holistic both in its outlook and in its approach to the problems of community health, In 2000, the Academy decided that its commitment to excellence in research required the setting up of an Institute that was dedicated to the pursuit of research and capacity development in St. John's. This vision encompassed improvement of health of the community and patients through research and development of a Center for Excellence in medical research in India

Post : Junior Research Fellow

Johnson & Johnson is the world’s most comprehensive and broadly based manufacturer of health care products. The organization is comprised of more than 250 operating companies with over 128,000 employees located in some 60 countries. With Global sales of USD 67.2 billion in 2012, Johnson & Johnson is recognized as one of the most admired and respected companies in the world.  In India, Johnson & Johnson operates as a single legal entity and consists of the 3 strategic business units: Consumer Products, Pharmaceuticals and Medical Devices & Diagnostics, which are independently managed and report into their respective Global business segments.  Ethicon Endo-Surgery is part of the Johnson & Johnson Family of Companies. We not only represent a history of innovation, but a rich tradition of patient care that begins with our parent company, Johnson & Johnson.

Post : Key Accounts Manager

Online applications are invited for the posts of Administrative, Non Teaching & Teaching Supporting at this Institute. For general terms, conditions and other important information please visit to Institute website: reckannauj.in

Post : Pharmacist - 1 UR post

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

SKS Group of Institutions (SKSgi) marked its expansion in Mathura with the start of Sanjay College of Pharmacy (SCP). SCP was established in the year 2007 and is located right along the Delhi-Agra NH#2, 125 Km from Delhi, 20Km from Mathura and 12Km from Vrindavan. Approved by AICTE - New Delhi, under Ministry of HRD, the Govt. of India.
While laying down the foundation of Sanjay College of Pharmacy it was visualized to create a benchmark of excellence in the field of education. At Sanjay College of Pharmacy we recognize the abilities of the student and try to help them grow and evolve as a successful professionals with moral and ethical values. This is made possible with the help of an experienced and dedicated team of faculty members and administrators. We have a strong liaison with the industries and blue chip companies so as to facilitate the placements of students.

Post: Principal, Professor, Assistant Professor, Lecturer