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A MAJOR APPROACH- 2-CHLOROPYRIDINE-5-TRIFLUOROMETHYL DERIVATIVE AS ANTIAMNESIC AGENTS

About Author:
Ravindra Singh Tomar
M.Pharm (Medicinal & Pharmaceutical Chemistry),
B R Nahta College of Pharmacy, Mandsaur (M.P)
ravindratomar16@gmail.com

ABSTRACT-
Here a scheme has been designed for synthesis of 2-chloropyridine-5-trifluoromethyl derivatives. The probability of being antiamnesic agent has been checked by pass prediction. All compound shows antiamnesic activity as result of pass prediction. By Lipinski rule of five all compounds shows drug like activity. Also a method for pharmacological evaluation & Biochemical evaluation is described under. All synthetic procedure has been designed & described under-

Application are invited from Pharmacist Gr-II in Kerala Public Service Commission | 8 Posts

The Kerala Public Service Commission is a body created by the Constitution of India.

Walk in interview for Chemists/Sr. Chemists/Officers Production in Zydus Cadila | 10 Posts

Banaras Hindu University invites Junior Research Fellow, Senior Research Fellow, Research Associate

Banaras Hindu University ranks among the first few in the country in the field of academic and research output. This university has two campuses, 3 institutes, 16 faculties, 140 departments, 4 advanced centers and 4 interdisciplinary schools.

THERAPEUTIC POTENTIAL AND FUTURE PROSPECT OF PSIDIUM GUAJAVA LINN

About Author:
Aarti Narkhede
Mahakal Institute of Pharmaceutical Studies,
Ujjain, MP
narkhede_aarti@rediffmail.com

ABSTRACT
The use of natural product has increased tremendously in a western world as well as in developing countries or in all over part of world. via this artical therapeutic potential and future prospect of Psidium guajava L. are described. Psidium guajava L. belonging to family, myrtaceae. It is a commen tree and easily found in a tropical countries or area. Traditionally it is a very popular and used from long time in a various system of medicine like, unani, Siddha, homeopathy and Ayurveda. It is used for treatment of many ailments like diarrhea, dysentery, wounds, rheumatism, lungs problems, ulcers, skin infections, vaginal discharge, epilepsy, menstrual pain, sore throat, mouth swelling, cold and cough, toothache and etc. In present time study on antipoliferitive or anticancer activities are undertaken and it is found that anticancer activity of P.Guajava has a four time greater than vincristine.

Job as Senior Team Member/ Team Member - PPIC in Mylan

Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline.

Opening for Business Heads in Akumentis Healthcare - High Profile Job

Akumentis have strong back up of world class manufacturing & R&D facilities. The manufacturing facility is 3rd largest in Asia with WHO GMP, ISO 9001, ISO14001, USFDA & UKHMRA certifications. we have 1000 innovative products in pipeline.

Post: Business Heads- Chennai

Walk in interview for the Post of Senior Research Fellow, Junior Research Fellow in Assam University

NMIMS - Shobhaben Pratapbhai Patel School of Pharmacy invites candidates for Ph.D Programme

The vision of NMIMS University is to define the 21st century technological and management research. Hence the goal for NMIMS University is to encourage excellence in research and publication activities.

Applications are invited for Entrance Examination for admission to Ph.D. Programme (Part Time) in Sri Ramachandra University

Sri Ramachandra University was established in the year 1985 as part of the Sri Ramachandra Education & Health Trust under the leadership of Shri N.P.V. Ramasamy Udayar. Ever since its inception, the institute grew from strength to strength gaining the status of a "Deemed University" in September, 1994 under Section 3 of the University Grants Commission Act, 1956.

A REVIEW: PLANTS AND HERBS USED IN ANXIETY

About Authors:
Awan Bharti*1, Sweta Gautam2
1Department of Pharmacognosy,
Shri Rawatpura Sarkar Institute of Pharmacy, Datia, M.P.
2Department of Pharmacognosy, RKDF College of Pharmacy, Bhopal
*bhartiawan@gmail.com, shwetagautam85@rediffmail

ABSTRACT
Interest in alternative medicine and plant-derived medications that affect the "mind" is growing. Anxiety affects one-eighth of the total population of the world and has become a very important area of research interest in psychopharmacology during this decade. Anxiety, a state of excessive fear, is characterized by motor tension, sympathetic hyperactivity, and apprehension and vigilance syndromes. Benzodiazepines are the major class of compounds used in anxiety and they have remained the most commonly prescribed treatment for anxiety, despite the important unwanted side effects that they produce such as sedation, muscle relaxation, ataxia, amnesia, ethanol and barbiturate potentiation and tolerance. Various types of herbal medicines have been used as anxiolytic drugs in different parts of the world. Folk medicines have particular values, for example, plants that "calm down", tranquilize, and raise mood, such as Passiflora coerulea, Valeriana officinalis, Matricaria recutita, Jatropa cilliata, Salvia guaranitica, Tilia tormentosa, and Tilia europeae. Plants have long been used to treat central nervous system (CNS) disorders.

“COMPARATIVE ANALYSIS OF VARIOUS PHYSICOCHEMICAL PROPERTIES OF MARKETED PARACETAMOL FORMULATION”

About Authors:
Sailesh Narayan*, Ankit Diwan
Sagar institute of Pharmacy and Technology,
Gandhi Nagar, Bhopal
*saileshcology@yahoo.co.in

INTRODUCTION
A tablet is a pharmaceutical dosage form. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from  a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment or to enhance the tablet's appearance. These are compressed tablets. formulated to deliver an accurate dosage to a specific site; it is usually taken orally, but can be administered sublingually, buccally, rectally or intravaginally. Medicinal tablets were originally made in the shape of a disk of whatever color their components determined, but are now made in many shapes and colors to help distinguish different medicines. Tablets are often stamped with symbols, letters, and numbers, which enable them to be identified.

South Eastern Coalfields invites Pharmacist (Trainee) | Government Job

South Eastern Coalfields Limited invites applications from the willing handicapped candidates who full fill required qualification for the following posts under National Coal Wages Agreement-IX.

Post: Pharmacist (Trainee)- General- 1

Application are invited from General Manager (Quality Assurance) in Central Medical Services Society

Central Medical Services Society, a Central Procurement Agency under Department of Health & Family Welfare, has been set up to procure and distribute health sector goods to the State Governments. The Society will be responsible for procuring goods worth about Rs 1000 crores annually and store them in warehouses across the country for distribution to State Governments for many National projects.

Walk in interview from Technical Assistant, Research Assistant in National Centre for Disease Control | 3 Posts

The National Institute of Communicable Diseases (NICD) had its origin as Central Malaria Bureau, established at Kasauli (Himachal Pradesh) in 1909 and following expansion was renamed in 1927 as the Malaria Survey of India. The organization was shifted to Delhi in 1938 and called as the Malaria Institute of India (MII).

LIQUISOLID COMPACT: A NEW APPROACH TO ENHANCEMENT OF DISSOLUTION OF POORLY WATER SOLUBLE DRUGS

About Authors:
Nareshkumar. G1*, A.Eashwar rao2, Ch.Ganga prasad3.
1*Center for Pharmaceutical Sciences, IST, JNTU Hyderabad, India,
2Talla Padmavathi College of Pharmacy, Warangal, India,
3National College of Pharmacy, Shimoga, Karnataka, India.
*nareshkumar62@gmail.com

ABSTRACT:
Liquisolid technique is a new and propitious method that can change the dissolution rate of poorly water soluble drugs. According to the new formulation method of liquisolid compacts, liquid medications such as solutions or suspensions of water insoluble drugs in suitable non-volatile liquid vehicles can be converted into acceptably flowing and compressible powders by blending with selected powder excipients. It has been speculated that such systems exhibit enhanced release profiles. In this case, even though the drug is in a solid dosage form, it is held within the powder substrate in solution or, in a solubilized, almost molecularly dispersed state, which contributes to the enhanced drug dissolution properties. Successful liquisolid tablet is a determination of optimal flowable liquid retention.

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A REVIEW OF MITRAGYNA PARVIFOLIA (ROXB) KORTH

About Authors:
Sharda roy*, vikas chandra roy, dr. R. C. Roy
Address Faculty of Pharmaceutical Sciences. Global College of Pharmacy.
Kahnpur Khui. Punjab.
*roysharda08@gmail.com

Abstract:
Mitragyna parvifolia
is a medium to large size tree belonging to the family Rubiaceae. It is popularly known as Kaim and is found growing gregariously throughout the drier parts of India, Pakistan and Srilanka. The aerial parts, stem-bark and roots of the tree contain various indolic (tetrahydroalstonine, akkuamigine, hirsuteine etc) and oxindolic (mitraphylline, isomitraphylline, pteropodine, isopteropodine etc) alkaloids. Important variations in the nature and quantity of alkaloids present in different parts of the plant are visible with change in geographical locations. In addition, various parts of the tree such as fruit juice, leaves and stem bark have been used in the traditional system of medicine by the natives and tribal since times immemorial. Mitragyna parvifolia has also got diverse medicinal and therapeutic properties such as analgesic, antipyretic, anti-inflammatory, antiarthritic, anthelmentic, antioxidant etc which have been validated scientifically. In this study we have critically reviewed the pharmacognostic and chemical profile, the traditional and the scientifically validated bioactivities of the plant.

Application are invited for the post of Senior Research Fellow in Indian Institute of Chemical Technology

Indian Institute of Chemical Technology, Hyderabad is a premier R&D Institute in India. The Institute had its origin as the Central Laboratories for Scientific & Industrial Research (CLSIR), established in 1944 by the then Government of Hyderabad State. After integration of Hyderabad State with the Indian Union, the laboratory expanded with its growing activities. The main building was formally opened by Pandit Jawaharlal Nehru, the then Prime Minister of India on January 2, 1954.

Job as Project Fellow in Osmania University

Osmania University, established in 1918, is the seventh oldest in India, the third oldest in south India and the first to be established in the erstwhile princely state of Hyderabad. Throughout its existence of over eight decades, it has shown remarkable progress and sustained an integrated development of all faculties. It has significantly contributed to the academic and economic development of not only the region but also of the Country.

Walk in interview for M.Pharm/M.Sc as Research Associate, Junior Research Fellow in Translational Health Science and Technology Institute

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