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(6th November, 2014; Business Wire India); Asia’s leading Discovery Research and Development organization, GVK BIO, announced the signing of a definitive agreement to acquire Vanta Bioscience, a full service preclinical GLP toxicology and safety assessment contract research organization operating out of Chennai, India.

(6th November, 2014); New Danish-led research suggests that signs of brain aging can be postponed in mice if placed on a high-fat diet. In the long term, this opens the possibility of treatment of children suffering from premature aging and patients with Alzheimer's and Parkinson's disease. The research project is headed by the Center for Healthy Aging, University of Copenhagen and the National Institute of Health.

(6th November, 2014); After successful 3rd clinical trial of Denue vaccine, Sanofi will file for registration of its vaccine candidate and, subject to regulatory approval, the world’s first dengue vaccine could be available in the second half of 2015.


Career for M.Pharm/M.Sc as Analytical Chemist in HLL Lifecare - Enterprise under the Ministry of Health & Family Welfare, Govt. of India

HLL Lifecare Limited, a Mini Ratna Central Public Sector Enterprise under the Ministry of Health & Family Welfare, Govt. of India is a global provider of high quality healthcare products & services. With state-of-the-art manufacturing facilities spanning across India, HLL is diversifying into vaccine manufacturing, lifecare services, sanitary napkins besides engaging in procurement consultancy, healthcare infrastructure development and facility management.

Career for B.Pharm, B.Sc as Patient Care Advisor @ Indegene

Indegene's scientific and competitive intelligence services lend actionable insights to clients to support their strategic decision making. We provide scientific, clinical, and competitive insights to help align the business development, licensing, clinical development, and marketing activities of our clients to current and future market needs.

Post: Patient Care Advisor

Work as Assistant Professors in Pharmaceutical Science at Assam University

Assam University came into existence through Assam (Central) University Act, 1989(Established under an Act of Parliament) . It was  established in 1994,since then  the University is steadily becoming  an excellent centre of learning.  The campus, situated in Dargakona, about 20 kms from  Silchar, is set amid sprawling hillocks, a typical landscape in the  North East. The campus  in an area of  600 acres surrounded by lakes and mountains provides  an ideal environment for academic pursuit.

Post: Assistant Professor in Pharmaceutical  Science (UR) (post code: Pharm.Sc/ATPS/3-2014/UR); Assistant Professor in Pharmaceutical  Science (ST) (post code: Pharm.Sc/ATPS/3-2014/ST)

Walk in at CSIR-URDIP | Require Project Fellows and Senior Project Fellows

CSIR has set up a Unit for Research and Development of Information Products (CSIR-URDIP) at Pune to work in the area of Scientific Informatics (ChemBioinformatics/ Patent Informatics/ Phytoinformatics/ Toxinformatics) and related software development projects.

Post: Project Fellow, Senior Project Fellow

Various project vacancies in CSIR-Institute of Genomics & Integrative Biology

CSIR-Institute of Genomics & Integrative Biology (IGIB) is a premier Institute of Council of Scientific and Industrial Research (CSIR), engaged in research of national importance in the areas of genomics, molecular medicine, bioinformatics, proteomics and environmental biotechnology.

Career for B.Sc, B.Pharm as Medical representative @ Leading for Pharma Company- Nextus Solution | 2 Posts

We are working with a leading pharmaceutical company in the world, a guarantee of internationally recognised quality. The achieved results are proof of an efficient strategy based on Research, Innovation and Internationalisation, along with the ability to recognize and meet the needs of physicians and patients alike.

Post: Medical representative- 2

Anna university invites Scientists for NHHID project - 2 posts

Anna University was established on 4th September 1978 as a unitary type of University. It offers higher education in Engineering, Technology and allied Sciences relevant to the current and projected needs of the society.Besides promoting research and disseminating knowledge gained therefrom, it fosters cooperation between the academic and industrial communities.The University was formed by bringing together and integrating two well-known technical institutions in the city of Madras.

Job as Technical- Manager Formulations in Chemfar Organics | B.Pharm/ M.Pharm

Chemfar Organics is 100% export oriented company, operating since 1998. Chemfar organics exporting pharmaceutical finished formulations (Tablets & Capsules) to SEA & CIS countries. The products are manufactured at contract manufacturing facilities.

Post: Technical- Manager Formulations

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Required for Junior Pharmacist in Institute of Liver and Biliary Sciences

Institute of Liver and Biliary Sciences (ILBS) has been set up as an autonomous super specialty Institute of excellence under GNCT of Delhi. Its vision is to be a global leader by becoming a beacon of patient care, teaching and research in the field of adult and pediatric Liver and Biliary Diseases. The Institute provides immense opportunities for career development and in its search for the best academic talent, invites applications on prescribed format for the following positions:

Require Pharmacist - Pharmacy in Narayana Health

In 2001, Dr. Devi Shetty Chairman - Narayana Health stepped in to make a difference to the Indian healthcare and he put into place a dream hospital project called Narayana Hrudayalaya that started modestly with 225 beds in Bangalore and went on to become a Health City with 3000 beds currently. In little over a decade the Narayana Health group grew exponentially into a multiple location hospital network with 26 hospitals across 16 cities in India with nearly 6900 beds as on date.

Opening for Pharmacist in CSIR-Indian Institute of Integrative Medicine

CSIR-Indian Institute of Integrative Medicine, Jammu, a constituent establishment of the Council of  Scientific & Industrial Research, under the Ministry of Science & Technology, Govt. of India, invites  applications for the following posts in the prescribed application form from the young and dynamic candidates, who have excellent academic record & experience in the given areas as per following details:

Career as Pharmacist (5 posts) in CHENNAI PORT TRUST

Chennai Port, the third oldest port among the 12 major ports, is an emerging hub port in the East Coast of India. This gateway port for all cargo has completed 128 years of glorious service to the nation’s maritime trade. Maritime trade started way back in 1639 on the sea shore Chennai. It was an open road -stead and exposed sandy coast till 1815. The initial piers were built in 1861, but the storms of 1868 and 1872 made them inoperative.

Job as Medical Representative in Soranus Lifesciences - Ahmedabad

Soranus Lifesciences is an innovative leading, vertically integrated pharmaceutical formulation company that discovers, develops, manufactures and markets a broad range of healthcare products. Headquartered in the city of Ahmedabad in India, The Company has dedicated research and development department well equipped with the latest equipments and supported by a large pool, of scientists who continuously work towards new pharma products.

Vacancy as MR in Soranus Lifesciences, Patan

Soranus Lifesciences, Our Corporate Group is associated with other business like leading Broking House of India, having vast exposure to Pharmaceutical Distribution since last 25 years along with chains of Retail Medical Stores and Infrastructure.  Our basic philosophy is to create care with lot of values.

BIOSIMILARS: SCALE UP FROM R&D TO COMMERCIAL STAGE

{ DOWNLOAD AS PDF }

ABOUT AUTHOR:
Madhusudan P Dabhole
Group Manager - BioProcess,
Richcore Life Sciences Ltd, Bangalore, Karnataka, India.
madhav888@rediffmail.com

ABSTRACT
The scale up of recombinant proteins involves a multi- dynamic strategic approach to achieve maximum output consistently. Various parameters during the fermentation will limit the synthesis of desired protein, which otherwise can be produced with ease in case of classical fermentation. In order to synthesis the protein, it is very important to understand the process at laboratory scale – both from scale up point of view and productivity improvement at large scale. Some of this parameters and scale up parameters are discussed below in this review.

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