Pharmaceutics Articles

About Authors:
Neha Tyagi*¹, N.V Satheesh Madhav^2
1KNGD Modi Institute Of Pharmaceutical Education And Reserach,
Modinagar-2 Uttar Pradesh, India
²Dehradun Institute Of Technology, Faculty Of Pharmacy,
Mussorie Diversion Road Village Makkawala PO Bhagwant pura -248009 Dehradun, Uttrakhand, India

About Authors:
Nitesh Solanki*, Ankit Chaudhary
Saraswati Institute of pharmaceutical sciences,
Dhanap, Gandhinagar.
*solankinitesh1188@gmail.com

ABOUT AUTHORS:
MR. Gunjegaonkar S.M., MR. Shelke T.T.
Assistance Professor.
Dept. of Pharmacology JSPM’s Charak College of Pharmacy and research,
Wagholi, Pune. Maharashtra.
*gunjeshiv@gmail.com

ABOUT AUTHORS:
Mayur Pansuriya*, DR. Amit Gupta, Vihar Gadhvi, Kathiriya Hashesh, Patel Chirag
Department of Quality assurance,
Mahatma Gandhi College of Pharmaceutical Sciences,
ISI-15 (A) RIICO Institutional Area,
Sitapura, Tonk Road, Jaipur-302022 (Rajasthan).
*mayurpansuriya45@gmail.com

ABOUT AUTHORS:
^*1Miss. Nikhil Lopez, ²Dileep K.J.
¹Final Year B.Pharm student
²Assistant Professor
College of Pharmaceutical Sciences,
Govt. Medical college, Thiruvananthapuram
*nikkylopez90@gmail.com

ABOUT AUTHORS:
*Naveen Kamboj¹, Sadanand Maurya², Sonia Kamboj³, Gaurav kumar Singh^2
1Chandigarh College of Pharmacy, Landran, Mohali, Panjab
²Transalam Institute of Pharmaceutical Education and Reaserch, Meerut, Uttar Pradesh
³ISF college of pharmacy moga, Punjab
*kamboj.naveen21@gmail.com

ABSTRACT
The most important method for developing the very stable and suitable formulation for thermolabile as well as thermostable drug is lyophilization which works on the principle of sublimation of ice crystal from frozen material. Principle of the process through the basis of formulation, freezing, primary drying and secondary drying . In order to design optimum lyophilization process, process development scientific need to the critical properties of the formulation and how to apply to this information to process design. Lyophilized formulation not only has the advantage of better stability, but also provide easy handling i.e. shipping and storage. This article present an overview of lyophilization process, its advantage and pharmaceutical application.

ABOUT AUTHORS:
Yogesh Kumar Jain*, Dr. R.P.S. Rathore, Udaibhan Singh Rathore, Dharmendra Singh sisodiya,  Vijendra Singh Chauhan
Bhupal Nobles’ College of Pharmacy,
Udaipur – 313002, Rajasthan, India.
*jain.yogesh1987@gmail.com

About Authors:
Hemant Rathod*, M.P.Khinchi, Dilip Agrawal, Natasha Sharma
*Department of Pharmaceutics
Kota College of Pharmacy,
Kota, Rajasthan, India
*hemant2787@gmail.com

Abstract
Fast dissolving, fast melting, chewable and orally dissolving or disintegrating tablets are solid dosage forms that disintegrate rapidly and dissolve in the mouth without water. These products have staying power in the marketplace because they appeal to consumers and support increased compliance among users as well as provide effective life-cycle management. The principle challenge with orally disintegrating tablets (ODTs) is to develop tablet formulations that deliver rapid disintegration, pleasant mouth feel and high breaking force for tablet robustness. Superdisintegrants affect a range of formulation parameters; including the rate of disintegration, tablet breaking force, and mouth feel i.e. Polyplasdone XL-10 superdisintegrant provides optimal performance in ODT formulations.