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6 November 2012

TRANSDERMAL PATCHES: A REVIEW

About Authors:
Patel Chirag J^1*, Satyanand Tyagi², Patel Jaimin¹
¹Maharishi Arvind Institute of Pharmacy, Department of Pharmaceutics, Jaipur, Rajasthan.
²President, Tyagi Pharmacy Association & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India.
*chirag.bangalore@gmail.com, +918000501871

ABSTRACT:
Now a day about 74% of drugs are taken orally and are found not to be as effective as desired either due to bioavailability problems or degradation of drug in acidic pH of stomach. To resolve such problems, transdermal drug delivery system (TDDS) was emerged. Transdermal drug delivery systems are dosage forms involves drug transport to viable epidermal and dermal tissues of the skin for local therapeutic effect while a very major fraction of drug is transported into the systemic blood circulation. Transdermal drug delivery systems, also known as ‘‘patches,’’ are dosage forms designed to deliver a therapeutically effective amount of drug across a patient’s skin. This review article provides an overview of TDDS, advantages, limitations, various components of TDDS, methods of preparation, types of transdermal patches, factors affecting transdermal permeation, evaluation parameters and new approaches in TDDS.

5 November 2012

Railway Recruitment Board -Mumbai invites Pharmacist-II - 16 Vacancies

Railway Recruitment Board (RRB), Mumbai functions under the Ministry of Railways, Government of India. It is primarily responsible for recruiting the group 'C' staff.

5 November 2012

PROBLEM: ENVIRONMENTAL POLLUTION AND GLOBAL WARMING IDEA TO IMPLEMENT GREENERY IN INDIA

The main problem which we are facing is the Global warming because of the polluted atmosphere. My idea can reduce the global warming and can bring back the polluted free environment

MAIN OBJECTIVE:
Converting the brown economy to green economy can be done very easily and fastly only by the Indian youth by starting an effective campaign by name “earth warriors” or some other easy feasible name so that everyone in India can understand the theme of the program easily unlike the other programs that we had earlier like great power race or carbon credit race etc., which takes time for the people to understand the theme of the campaign.

5 November 2012

Multiple vacancies in Institute of Genomics & Integrative Biology | 8 Posts

Institute of Genomics & Integrative Biology (IGIB) is a premier Institute of Council of Scientific and Industrial Research (CSIR), engaged in research of national importance in the areas of genomics, molecular medicine, bioinformatics, proteomics and environmental biotechnology.

5 November 2012

Application are invited from eligible candidates for the post of Research Associate in National Brain Research Centre

The National Brain Research Centre (NBRC) was established by the Department of Biotechnology, Ministry of Science & Technolgy, Government of India, in November 1997 as a fully funded autonomous research institute in the area of neuroscience and brain. The Centre was registered as an Society in June 1999 under the Registration of Societies Act.

5 November 2012

Job as Executive in Finition Solutions | 5 Posts

With the bricks of inveterate faith in ourselves was laid the foundation of Finition Solutions, Rising from a small Consulting company that planted its roots in the Nawabs or pearl City Hyderabad / India, Finition Solutions has grown over the years into a dynamic medium-sized business activities spanning through India, UK and USA.
Finition Solutions is involved in businesses as diverse as HR Services, Information Technology, Manufacturing and Bio (Environmental Solutions).

5 November 2012

PREPARATION & EVALUATION OF MICROSPHERES OF DICLOFENAC SODIUM BY SURFACE ACTIVE AGENT SLS

About Authors:
*Kalpesh Ashara, Jignesh Solanki
B.K.Mody Govt.Pharmacy College Rajkot,
Department of Pharmaceutics,GTU, Gujarat, India.
*kalpeshshr5@gmail.com

Abstract:
Microspheres are solid spherical particles containing a dispersed drug in organic solution fall in a range of 1-1000mm. Microspheres or micro particles are monolithinic device refer to a rate controlling matrix throughout the drug is dissolved or dispersed, while microcapsules are device which consists of cell-like dosage forms with the drug contain within the rate controlling membrane. Microspheres are prepared by several methods. Here Microspheres are prepared using a surface active agent SLS. Then Evaluation of Microspheres is carried out by means of several parameters. Then concluded that the diclofenac: polymer ratio of 1:2 & organic solvent (MeOH: DCM) ratio of 1:4 was found to be optimum for spherical shape of microspheres as well as Practical Yield.

5 November 2012

PREPARATION OF VILOXAZINE SUSTAINED RELEASE DRUG DELIVERY SYSTEM BY USING ETHYLCELLULOSE, CARBOPOL, SODIUM ALGINATE, HYDROXY PROPYL METHYL CELLULOSE & GUAR GUM

About Authors:
D. HariHaran*, M. Senthil kumar, M. Ashok Kumar, S. Dinesh & R.Jenish.
Annai Veilankanni’s College of Pharmacy,
81, V.G.P. Salai, Saidapet, Chennai-600015.
*haran_pharma@yahoo.com

ABSTRACT
The present study behind this work is to find to prepare sustained release tablets of Viloxazine by compression method. First of all to formulate Viloxazine sustained release tablets using the Ethylcellulose, Carbopol, Sodium Alginate, Hydroxy propyl methyl cellulose & Guar gum under ratio’s like 1:1, 1:1, 1:1,1:1,1:1 . Five batches were made in various polymers of ethylcellulose, carbopol, sodium alginate,hydroxy propyl methyl cellulose & guar gum is used by keeping the drug as constant. Then evaluation of Viloxazine sustained release tablets was carried out for characteristics like drug content in tablet, UV analysis. In vitro release starts from 1hr and up to 24hrs. It shows the percentage of gradual drug release as 17.80%, 27.65%, 35.12%, 45.16%, 51.20%, 57.42%, 61.30%, 66.32%, 72.08%, 77.15%, 81.32%, 84.48% & 98.20% against the label claim as 40mg.

4 November 2012

Opening in Contractual Scientist - Pharmacy/Pharmaceutical Chemistry/Analytical Chemistry , SRF and JRF in GBPUAT - 5 posts

Applications are invited for the posts of PDF (Contractual Scientist), Senior Research Fellow (SRF) and Junior Research Fellow (JRF) in the Institute of Biotechnology, G.B. Pant University of Ag. & Tech., Patwadangar (Nainital). The monthly emoluments and qualifications for the above posts are as follows:

4 November 2012

The National Institute of Biologicals invites Scientist Grade-I, II and Jr. Scientist - 3 Posts

The National Institute of Biologicals, an autonomous institution under the Ministry of Health & Family Welfare, Government of India is a premier scientific organization and a Centre of excellence to ensure quality of vaccines and biologicals in the country. Applications are invited for the following scientific posts on Direct recruitment basis.

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November 2012

TRANSDERMAL PATCHES: A REVIEW

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