November 2012

National Institute for Research in Reproductive Health (NIRRH), formerly known as Institute for Research in Reproduction is a premier research institute of the Indian Council of Medical Research (ICMR). It is situated in the vicinity of a number of hospitals and research institutes in central Mumbai. Since its inception in 1970, it has been making vigorous efforts to improve the reproductive health of people through research, education and health care services.

Leading company specialized in Medical Equipment, Electronic Weighing and Corporate Promotional Products located in Mumbai. Our client  is an ISO certified company and broadly caters to three categories – Medical Equipment, Electronic Weighing and Corporate Promotional Products. our client has their own manufacturing facilities at Rabale, Navi Mumbai with in-house R&D, Design and Production.

About Authors:
Arshad Hala*, Prof. Rajesh Dholpuria, Nilesh Sovasia
¹Seth G. L. Bihani S. D. College Of Technical Education,
Institute Of Pharmaceutical Sciences & Drug Research,
Gaganpath, Sri Ganganagar, Rajasthan 335001
*Arshad_hala@yahoo.com

1. INTRODUCTION:-
1.1. Origin:-
Contract manufacturing is defined as the manufacture (or partial manufacturer) of a product to the order of one person or organization (the contract giver or customer) by another independent person or organization (contract acceptor or principle manufacturer). Manufacture in this context is identified as the act of processing or packaging a medicinal product or device to a given specification.(Shah, D.H., 2000)

Contract manufacturing should be consideration as an extension of the principal manufacturer’s operation. Consequently the principal manufacturer should require the same standards of good manufacturing practices (GMP) for a contractor’s operation as he would his own. In addition, the customer must ensure that the principle manufacturer holds the relevant legal authorizations for the work to be carried out.(Shah, D.H., 2000)

The responsibility and activities undertaken by each party need to be clearly stated in a formal agreement, separate from but additional to the legal business contract formed by the placement of an order. Commercial matters need to be appreciated as being distinct from technical matter and need to be detailed separately with due consideration for compliance with local legislation.(Shah, D.H., 2000)

About Authors:
Patel Chirag J^1*, Satyanand Tyagi^2
1Maharishi Arvind Institute of Pharmacy, Department of Pharmaceutics, Jaipur, Rajasthan.
²President, Tyagi Pharmacy Association & Scientific Writer (pharmacy), Chattarpur, New Delhi, India.
*chirag.bangalore@gmail.com, +918000501871

ABSTRACT
The basic rationale of sustained release drug delivery system optimizes the biopharmaceutical, pharmacokinetic and pharmacodynamic properties of a drug in such a way that its utility is maximized, side-effects are reduced and cure of the disease is achieved. There are several advantages of sustained release drug delivery over conventional dosage forms like improved patient compliance due to less frequent drug administration, maximum utilization of the drug, increased safety margin of potent drug, reduction of fluctuation in steady-state drug levels, reduction in healthcare costs through improved therapy and shorter treatment period.Presently pharmaceutical industries are focusing on development of sustained release formulations due to its inherent boons.Wide varieties of polymers are available for retarding the release rate of drugs hence sustains the action of drugs. This article contains the basic information regarding sustained-release formulation, its advantages, different types, and characteristics involved in oral sustained-release dosage form design.

UKPSC invites to fill up opening in group B and C, which is mentioned as below. No. of vacancies may increase or decreased.

Post: Drug Inspector, Senior Analyst, Junior Analyst, Lecturer of Pharmacy / State Polytechnic

bioCampus, GVK Biosciences is leading Informatics Services provider with wide range of Products and Services across the R&D value chain.

Applications are invited for the position of SRF in ICMR sponsored project: "The study of mitochondrial dynamics during S aureus infection in human epithelial cells" with Dr. Rajesh Singh, Assistant Professor, Cell Biology Group, IIAR.

Post: SRF (One post)