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April 2011

 

 

academics

 

Clinical research courses

Product Executive / Manager For Pharma Require @ Naprod Life Sciences Pvt. Ltd.

Naprod’s vision is to become a world class player in oncology through excellence in innovation, discovery of new manufacturing processes / drug delivery mechanisms and consistently high quality of production. We commenced operations in 1994 with the inauguration of our ultra-modern facility for the production of generics and formulations for oncology and other therapeutic applications. We are one of the pioneers in India in lyophilization.

Trainee Require in Pharmaceutical Department @ Marion Biotech - 4 Openings | Freshers

Marion Biotech strongly believes in an integrated approach to healthcare. It is also engaged in extensive Research & Development of unique Herbal products. At Marion Biotech, we set Stringent Standards of Quality, Safety and Efficacy for all the Products that we manufacture.

Job as a Quality Control Executive in Healthy Life Pharma Pvt. Ltd

Healthy Life Pharma has an excellent state-of-the-art infrastructure unit situated in Tarapur Industrial Area, Mumbai, India. The production plant has WHO-GMP certification for its compliance to international standards of manufacturing. Not only this, but it also meets the cGMP norms, put in the "Revised Schedule M" by the Drug Controller (General) India, Ministry of Health, Government of India.

Work as a QA/QC Executive in R&D Department @ Venus Remedies Limited

Venus start each day by focussing on Innovation & Creativity. We make sure that best healthcare is provided to our patients worldwide.
From a humble beginning in 1991, now we are engaged & engrossed in discovering, developing and delivering innovative pharmaceuticals that help patients to alleviate sufferings.
Venus spans its wings across the globe. We are present in 60 nations and are helping sufferers in their fight against cancer, meningitis,cardiovascular diseases and other sufferings.

Lawsonia inermis - From traditional use to scientific assessment

About Authors: Inder Kumar Makhija
Department of Pharmacognosy,
Manipal College of Pharmaceutical Sciences,
Manipal University, Manipal-576 104,
Karnataka

ABSTRACT
The world is endowed with a rich heritage of medicinal plants. The use of medicinal agents presumably predates the earliest recorded history. Medicinal plants are widely used by traditional practitioners for various ailments. Lawsonia inermis (Lythraceae) commonly known as ‘Henna’is a well-known plant used in the Indian medicine. Various parts of this plant have been used in traditional Indian medicine. The plant has wide range of phytochemicals including lawsone, isoplumbagin lawsoniaside, lalioside, lawsoniaside B, syringinoside, daphneside, daphnorin, agrimonolide 6-O-β-D-glucopyranoside, (+)-syringaresinol O-β-D-glucopyranoside, (+)-pinoresinol di-O-β-D-glucopyranoside, syringaresinol di-O-β-D-glucopyranoside,  isoscutellarin3β, hennadiol, (20S)-3β, 30-dihydroxylupane, lawnermis acid, 3-methyl-nonacosan-1-ol, laxanthones I, II, III and lacoumarin etc. The various in-vitro and in-vivo studies of L. inermis reported the plant to have antibacterial, antifungal, antiparasitic, antiviral, anticancer, antidiabetic, tuberculostatic, anti-inflammatory, antifertility and wound healing properties. This review discusses on the botany, traditional use, phytochemistry and pharmacological data of the plant.

A Brief overview on ImmunoPharmacology and Study of Drugs on Immune System

About Author: Bharat Lal
MSIP,
Delhi

STUDY OF DRUGS ON IMMUNE SYSTEM: IT MAY STIMULATE THE IMMUNE SYSTEM OR SUPPRESS THE IMMUNE SYSTEM. STIMMULATION IS REQUIRE FOR DISEASE LIKE AIDS AND SUPPRESSION IS REQUIRE FOR ORGAN TRANSPLANTATION.

Stress Induced Method Development and Validation of Olmesartan in Bulk and Pharmaceutical Dosage Form by UV Spectrometric Method

About Authors: 1Arun Kumar Dash*, 2Amitesh Palo,
1. Royal College of Pharmacy and Health Sciences, Berhampur.
2. College of Pharmaceutical Sciences, Mohuda, Berhampur

ABSTRACT
A simple method for the estimation of Olmesartan in bulk and pharmaceutical dosage forms has been developed. Methanol was chosen as the solvent system. The λmax was found to be 257nm and all absorbance values were carried out at 257nm. The responses were linear in the range of 5-35µg/ml. The regression equation of the calibration graph and correlation coefficient were found to be y = 0.049x + 0.007 and 0.999 respectively. The %RSD values for both intraday and interday precision were less than 1%. The recovery of the drug from the sample was ranged between 99.36 and 100.49%. The proposed method was validated for precision, accuracy, intraday, interday assay, robustness and ruggedness. Commercial tablets containing 20mg and 40mg of Olmesartan were analyzed by the proposed method and the results were well within the claimed limits. Furthermore stability studies of Olmesartan were carried out under acidic, alkaline, hydrolytic and photolytic conditions as per SIAM (Stability Indicating Assay Methods).

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Synthesis and biological evaluation of newer analogues of 2,5-disubstituted 1,3,4-oxadiazole as antioxidant and anticonvulsant agents

About Authors: Arun Dureja*, Kalpana Divekar and M.S.Sandhyavali
Department of Pharmaceutical Chemistry,
Dayananda Sagar College of Pharmacy,
Kumaraswamy Layout,
Bangalore

Abstract
A series of 3-(4-acetyl-5H-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)- 2H-chromen-2-one derivatives were synthesized and evaluated for their anticonvulsant and antioxidant activities. Initially Ethyl-2-oxo-2H-chromene-3-carboxylate was prepared by reacting Salicylaldehyde with Diethyl malonate in presence of piperidine. This compound was treated with hydrazine hydrate to give aromatic hydrazides. Those hydrazides were refluxed with different aldehydes to form arylidines, which were then treated with acetic anhydride to form 3-(4-acetyl-5H-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)- 2H-chromen-2-one derivatives. The structures of synthesized compounds were characterized and confirmed by IR and 1HNMR and then screened for antioxidant activity by DPPH reduction method and anticonvulsant activity by MES method. The investigation revealed that out of eight newly synthesized derivatives five were found to possess significant anticonvulsant activity but none of the derivative was found with antioxidant activity.

ESTIMATION OF QUETIAPINE FUMARATE IN TABLET DOSAGE FORM BY HPTLC METHOD

About Authors: Deepak Sahu
M.Pharm, Geetanjali Institute of Pharmacy
Dabak,
Udaipur, Rajasthan

ABSTRACT
A simple, accurate, low cost and specific HPTLC method for estimation of quetiapine fumarate in tablet has been developed. It was performed on Silica gel G60 F254 aluminium foil using acetonitrile : chloroform in the ratio of 1:9 as mobile phase. The mobile phase having chamber was saturated for 20 minutes at room temperature. The Rf value of quetiapine fumarate was found to be 0.45. The plate was scanned and quantified at 242 nm. The calibration curve response was observed between 5-25 μg. The linear regression data showed good linear relationship of r = 0.999. The percent recovery was found to be 100.0 ± 0.01.The developed method was validated for its accuracy and precision with suitable parameters.

Walk in @ National Institute of Pharmaceutical Education and Research for the post of RA / SRF

NIPER is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’.