Miscellaneous Articles

7 May 2017

MULTI ORGAN DYSFUNCTION FOLLOWING CONSUMPTION OF TUBERS OF GLORIOSA SUPERBA : A RARE CASE REPORT

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ABOUT AUTHORS
^*K. Vinod¹, B, Dr. N. Surendra Reddy¹,Dr. K. Chandra Sekhar², Dr. D. Ranganayakulu¹
¹Department of Pharmacy Practice,
Sri Padmavathi School of Pharmacy,
Tiruchanoor, Tirupati, India.
² Department of General Medicine,
Sri Venkateswara Medical College,
Tirupati, Andhra Pradesh, India .
*drvinodkatiboina@gmail.com

ABSTRACT:
A 25 years married man was admitted on to emergency acute medical care unit. He had fallen ill after an afternoon meal from 4 days ago which consisted of rice and 3 tubers identified as gloriosa superb. About 3hrs after the ingestion, he developed abdominal pain, vomiting (15-20 episodes), and watery diarrhoea 15-20 episodes. He developed bleeding gums, yellowish discoloration, hematemesis 30-50 ml, 24episodes, haematuria, decreased urine output along with continued diarrhoea and vomiting. He was treated with iv fluids crystalloids and colloids titrated, 1 fresh frozen plasma (FFP), 1fresh platelet transfusion, inj. vit K, supportive treatment with close monitoring of vitals. Therapy as planned for ventilator support, however had ever had bleeding per rectum and hematemesis with aspiration, even with best available resuscitative efforts he succumbed to his illness and declared clinically dead after 36hrs of admission, his cause of death was given as multiorgan dysfunction see to gloriosa superb. Though poisoning with gloriosasuperba is rare it is mostly fatal and requires aggressive and prompt treatment is mandatory from saving the patient from death.

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18 April 2017

GOODS AND SERVICES TAX (GST) in Indian Pharmaceutical and Its Impact on Industry

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ABOUT AUTHOR
Neha Bala, Naresh Mali*
Institute of Health Management Research, Jaipur
Rajasthan, India
malinaresh888@gmail.com

“GST will be the best example of co-operative federalism. Together we will take India to new heights of progress. We continue to work with all parties and states to introduce a system that benefits all Indians and promotes a vibrant and unified national market. This reform will promote ‘Make in India,’ help exports and thus boost employment while providing enhanced revenue.” — Prime Minister of India, Mr. Narendra Modi, 3rd August 2016
14 February 2017

A STUDY ON ROLE OF CLINICAL PHARMACIST IN IDENTIFICATION AND REPORTING OF DRUG INTERACTIONS IN PHYSCIATRIC WARD IN A TERITARY CARE TEACHING HOSPITAL

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ABOUT AUHTORS
M. Manasa Rekha*, T. Mubeena
Department of Pharmacy Practice,
Annamacharya college of Pharmacy,
Rajampet, Andhra Pradesh, India.
* manasarekharoyal@gmail.com

ABSTRACT:
Clinical pharmacy is defined as that area of pharmacy concerned with the science and practice of rational medication use. The pharmacist, along with the prescriber has a duty to ensure that patients are aware of the risk of side effects and a suitable course of action should they occur. With their detailed knowledge of medicine, pharmacists have the ability to relate unexpected symptoms experienced by patients to possible drug interactions of their drug therapy. The practice in clinical pharmacy also ensures that drug interactions are minimized by avoiding drugs with potential side effects in susceptible patients. Thus, pharmacist has a major role to play in relation to prevention, detection, and reporting drug interactions.
14 July 2016

A REVIEW ON USFDA WARNING LETTER AND VIOLATION OBSERVED IN PHARMACEUTICAL INDUSTRY

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ABOUT AUTHORS
Suleman S. khoja ¹, Sohil S khoja¹,Parthkumar H chauhan²,Farhad S Khoja
¹Resource person in pharmaceutical quality assurance ,VAPI, Gujarat.
²Resource person in quality assurance ,NAVSARI, Gujarat.
³Registered Pharmacist ,VAPI, Gujarat.
premukhoja@gmail.com

ABSTRACT
A review on USFDA observation and finding while inspection of Pharmaceutical the present review provide some important , Significant observation and measure of compliance.USFDA is an regulatory body governing health products which are made ( in or outside USA) and marketed in united States of America. Significant deviation from cGMP and Significant violation from cGMP for both API Facility and formulations .strictly compliance requirements under 21 Code of federal regulations (CFR). FDA observation includes but not limited to this. If not cleaned and maintained equipment at appropriate intervals to prevent contamination that would alter the Safety, Identity, Strength, Purity and Quality of drug product (SISPQ) ,violation under [ 21 CFR & 211.67 (a) ]. Data integrity is main issue Raised in most FDA warning letter. Corrective action and plan. Level of control must be raised from raw material, packaging material (Accurate, Legible, Contamptarious, Original, Attributable (ALCOA)) in process, finished dosage form, Maintain log book properly. Guidelines for Out of specification(OOS ) and out of trends(OOT) must be follow if any required.
6 December 2015

REVIEW STUDY ON FACTORS AFFECTING THE PRESCRIPTION PATTERN OF PHYSICIANS

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About Authors
Amoah-Binfoh Kenneth^1*, Pradhyuman Singh Lakhawat¹, Archana Chandra²
¹ SHIATS, Allahabad, UP, India
² Dept. of Human Resources, SHIATS, Allahabad, UP, India
* geokin08@gmail.com

ABSTRACT
Prognosis the medical outcome of a corrective prediction, physicians become aware of a particular drug through promotional strategies. If all relevant information received is positive, the drug may be tried on few patients’. As a matter of fact if the outcomes of the trials are acceptable physicians will shift and may be more interested to prescribe the drugs consistent. Prescribing drugs is a standard component of most physicians’ practices. It is an important area of practice that requires appropriate knowledge, skill and professional judgment. To improve patient safety when prescribing, these qualities set out expectations for physicians who prescribe drugs. However in connection with the physician’s prescription pattern, Indian pharmaceutical industry is at a turning point. The pharmaceutical firms have to change their strategies for the challenges ahead. Quality systems, innovation, manufacturing and marketing competence are associate factors that affects physicians prescription pattern. The efficacy of drug discovery process has been reported to have suffered a major transformation. New drug discovery has to be strictly adhere to the tight intellectual property rights to ensure effective and efficient, prescriptions and protections. Further clinical and behavioral characteristics of the patient, research and the pressures from drug firms, high curing effect; habitual or non-habitual choice, behavior pattern of patients, peer influence of physicians (community of physicians) and education and advertising are reviewed factors affecting physician’s prescription pattern.
12 November 2015

A REVIEW ON: PHYSICOCHEMICAL EVALUATION OF AYURVEDIC MINERAL DRUG TANKAN BHASMA

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2 October 2015

SEARCHED FOR CANCER CURE, FOUND IT EVERYWHERE !

ABOUT AUTHOR:
Vishwas B. Chawan
Consultant at Clinical Diagnostic Centre,
Mumbai, Maharashtra
vishwaschavan2003@yahoo.co.in

Cancer is called “Emperor of All Maladies.” Finding cure for cancer is one of the most important goal of medical research. Cancer is among the leading causes of morbidity and mortality worldwide. Globally, in the year 2012, cancer affected 14 million new people and 8.2 million people died from cancer or cancer-related complications^[1]. Current cancer therapies are costly and have many side effects. Additional problems are development of resistance to treatment and recurrence of cancer even after initial successful treatment.
22 September 2015

IMPACT OF RIGHT TO EDUCATION (RTE) ON ACCESS AND QUALITY OF EDUCATION

ABOUT AUTHOR:
Nirav Rajendrakumar Soni
M.Pharm (QA), PGDIPR
Ahmedabad, India
nirav_sonic@yahoo.com

ABSTRACT:
The importance of education cannot be denied in one’s life. It sustains the human values which supply to the individual and collective good. The relationship between universal human rights and educational equity and access within the context of the educational system It forms the origin for lifelong learning and inspires buoyancy to face challenges. It will give the skills to individuals to become more self-reliant and aware of right opportunities. It also enhances the ability of individuals to act more responsible and more informed citizens and have a voice in politics and society, which is essential for sustaining democracy. The importance of primary education has been neglected by India since independence knowingly or unknowingly. However, Government of India now is willing to improve primary education by bringing legislation i.e. Right to Education. But efforts through Right to Education (RTE) to improve the quality of school education seem to be yielding little result. The learning outcome in reading, writing and arithmetic is becoming poorer and enrolment in private schools is improving significantly, indicating a growing distrust of the common man against state-run schools in the country. This paper tries to bring out the meaning of much awaited Right to Education (RTE) 2009, act and tries to bring out the critical appraisal of the Act after five years since its passage.
13 September 2015

BIODEGRADABILITY AND WASTE MANAGEMENT OF JAIPUR FOOT

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ABOUT AUTHORS:
Anil Kumar Jain¹*, Mona Kejariwal²
¹ Dr. P.K. Sethi Rehabilitation Centre, Santokba Durlabhji Hospital, Jaipur, Rajasthan, India
²Department of Botany, R.D. National and W.A. Science College, Bandra (west), Mumbai, India.
*anil.rehab64@gmail.com

ABSTRACT
Designed in and named after Jaipur, India, the prosthetic foot was designed to be inexpensive, water-resistant, and quick to fit and manufacture. Several field trials case studies were made and this artificial aid was found to be very comfortable and acceptable to the amputee population following floor sitting culture. The quality assertion and standards related to these prostheses at affordable cost assume great significance especially for India and other developing countries. Environmental issues such as biodegradability of various components like microcellular rubber, tread rubber, nylon cord, cushion compound and skin colour rubber and other. It is necessary that biodegradation issues should be widely held at various platforms beside its bioengineering and designing issues for proper handling and storage concerns. Approval standards and quality control should be a part of the development effort prior to regular production and use of these low cost prostheses.
20 August 2015

DATA INTEGRITY NON-COMPLIANCES – THE GOOD, BAD AND UGLY

ABOUT AUTHORS
Krishnendu Singha
Manager – Quality Assurance
[The author is a Quality Assurance professional of a leading MNC]
Krish_singha2007@yahoo.co.in