CYCLODEXTRINS AND ITS RECENT ADVANCES: AN OVERVIEW
About Authors:
Virag A. Shah1*, Tarashankar Basuri1, Vishal S. Modi1, Rohit R. Shah2, Dhananjay S. Ghodke2
1 SSR College of pharmacy, Silvassa, U.T of Dadra & Nagar Haveli-396230
2 Appasaheb Birnale College of Pharmacy, Sangli, Dist: Sangli, Maharashtra- 416416
*viragshah687@gmail.com
Abstract:
Cyclodextrins (CDs) due to their inclusion formation ability finds wider applicability in Novel Drug Delivery Systems as well as in Pharma industries. This review highlights and focuses on history of CD molecules, their chemistry, need for derivatizations of CDs, production method, CDs inclusion complexes and various methods used for complexation. The article also focuses on various effects of CDs on drug solubility and dissolution, bioavailability, stability, and safety. Some important drug delivery systems which utilize CDs are also summarized with a brief overview on recent advances in CDs.