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Evaluating Cassia tora Linn. Seeds for their Antimicrobial Potential with Special Reference to Skin Infections

About Author: Saurabh Jain.*1, M.D.Kharya and Jain Aakansha2
1 Department of Pharmaceutical Sciences
2 Department of Microbiology
Dr. H. S. Gour Central University Sagar (M.P.), India.470003

Abstract
Due to increasing resistance to existing synthetic antimicrobial agents, herbal drugs are being looked as importance source for treating various ailments related to skin infections and also for the discovery of new antimicrobial molecules for their synthesis. Cassia tora is a well known plant possessing wide range of pharmacological activities. It has been used in India as folk remedy in the form of decoctions and infusions to treat bacterial and fungal infections and also claimed to be effective against variety of skin conditions like psoriasis, acne, wounds etc. Although this plant, particularly its seeds have been reported to have antimicrobial activities, but no targeted and specific study has been reported. The present investigation was carried out to study this unexplored area of this drug. As the seeds of C. tora possess good antimicrobial activity, it was thought worked to scientifically explore its potential on microorganisms effecting human beings especially on skin, so that safe and effective herbal treatment can be developed for the same.

Requirement of Senior Editor & Editor at Thakur Publication Pvt. Ltd. - Fresher | Walk-in

Thakur Publishers as a venture was established by a group of students of MBA, and who are founders also, to publish first studynotes cum text book for the aspirant studying students of the U.P. Technical University, which had come in existence just after 2 years of establishment of UPTU, when the group of students, while studying for the semester examinations were guideless both from teachers as well as from the market as no book was available of any publication.

Require Regulatory Manager II / III, Emerging Diseases Franchise in Novartis

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

A Novel Approach for the Treatment of Migraine

About Author: Shishir Tripathi
M.Pharm-Pharmaceutics
Department of Pharmacy,
Barkatullha University,
Bhopal-462026, M.P., India

Abstract
According to the Migraine Research Foundation, migraine ranks in the top 20 of the world’s most disabling medical illnesses with more than 10 percent of the population, including children, suffering from the migraine. Sumatriptan Succinate is a choice of drug used for the treatment of migraine when received at oral dose its bioavailability is approximately 14%. Considering the low bioavailability after oral and intranasal administration, due to presystemic metabolism and incomplete absorption as well as additional inconveniences associated with parenteral and oral administration, the exploitation of an alternative route of sumatriptan delivery, such as transdermal administration (topical gel)—could be sort out mentioned problem and enhance its therapeutic benefit up to most possible extent. Topical delivery systems of Sumatriptan succinate gel were formulated using polymers like HPMC, Carbopol 934 and Pectin and penetration enhancers like eucalyptus oil, menthol and oleic acid. The gels were evaluated for various parameters such as homogeneity, grittiness, extrudability, in vitro drug release, viscosity, pH, spreadability and drug content. The release rate of the gel was found to obey koresmeyer peppas kinetics. It can be concluded that HPMC gel has properties similar to marketed preparation and eucalyptus oil acts as a good penetration enhancer in Sumatriptan gels as compare to menthol and oleic acid.

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Memory Enhancing Activity of Methanolic Extract of Selaginella Bryopteris in Swiss Albino Mice

About Author: Neeraj Kumar Garg*1, Pankaj Khatri1, Sangeeta Gupta2, N. Ganesh2
1. School of pharmacy, Suresh Gyan Vihar University, Mahal, Jagatpura, Jaipur (Raj.)
2. Incharge, Department of research, jawahar lal Nehru cancer Hospital and Research centre, Idgah hills Bhopal 462001 (M.P.)

Abstract
Alzheimer disease (AD) is a neurodegenerative disorder currently without an effective treatment. Impairment of memory is the initial and most significant symptom of Alzheimer disease (AD). The present study was under taken to investigate the effect of Selaginella bryopteris (popularly known as sanjeevani, Family: Selaginellaceae) on learning and memory. Two doses (250 and 500 mg/kg p.o.) of methanolic extract of Selaginella bryopteris were administered for 7 successive days in separate group of animals. The dose of 500 mg/kg p.o. of the methanolic extract of Selaginella bryopteris significantly improved learning and memory of mice. Antioxidant property of Selaginella bryopteris may be contributing favourably to the memory enhancement effect. However, further studies are necessitated to identify the exact mechanism of action. In the present investigation of Selaginella bryopteris have shown promising memory enhancing agent in the entire laboratory models employed.

Opportunity to Work as Associate Pharmacist - Drug Delivery Research Laboratory @ USV Limited - 3 Posts

USV is aleading healthcare company with the following areas of focus: Generics, Active Pharmaceutical Ingredients (APIs) and Biosimilars. 68% of our business is contributed by India Operations and the rest by export of APIs and Generics.

Sahyadri Hospitals looking for Pharmacist

Sahyadri Hospitals is the largest chain of hospitals in Mahrashtra. It is always within easy reach due to its strategic locations which include cities like Pune, Nashik, Karad and Navi Mumbai.
Sahyadri group has 10 Hospitals with more than 860 beds currently and plans to expand to almost 1200 beds by end of the next financial year. Sahyadri has touched the lives of over 10 lakh people by providing quality care.

Requirement of Professional Services - North & East at Novartis

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Applications are Invited for the Post of Junior Research Fellow in Jawaharlal Nehru University

The JNU campus is a microcosm of the Indian nation, drawing students from every nook and corner of the country and from every group and stratum of society.

Government of Canada Invites Applications from Indian Scholars for the Doctoral Research Fellowship 2012-2013

The Foreign Affairs Canada, Government of Canada, through Shastri Indo-Canadian Institute, invites applications from Indian scholars for the following fellowship:

(A) Understanding Canada: Faculty Research Fellowship 2012-2013

Opportunity to Work as RMW Group Leader (GL) @ Novartis

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Calyx Chemicals and Pharmaceuticals Limited looking for Manager - Analytical Development Lab

CALYX is an US FDA inspected Active Pharmaceutical Ingredient manufacturer with excellent custom synthesis capabilities. Corporate head quarter is located in the commercial hub of India – Mumbai with its manufacturing facilities on the outskirts of Mumbai.

Opportunity to Work as Production Officer, R&D Chemist and Microbiologist / QA - QC Chemist at Ultra Beauty Care Pvt. Ltd.

Ultra Beauty Care Pvt. Ltd. (UBCPL), is part of the Machhar Group of industries. The group is primarily based out of Aurangabad, Maharashtra with concentration in the Packaging Industry. Apt Packaging Ltd - Formerly ANIL TUBES, a Machhar Group company is the largest manufacturer of Co-Extruded Plastic Tubes in India with a global client list of Cosmetics & Toiletries manufacturers.

Post for Manager / Senior Manager - QA @ Windlas Biotech Ltd.

Windlas Biotech Limited is an independent contract manufacturer serving the Indian and international pharmaceutical industry. They are a company of professionally alive, forward looking and committed team members serving the medical fraternity. Their primary focus is to consistently meet the global manufacturing requirements of their customers by providing cost-effective services and delivering quality products efficiently and reliably.

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