About Author: Ashish Kumar Verma¹, D.Raj. Anand¹, Garima A. Tewari²
1.    Jubilant Chemsys Limited Noida 201301
2.    Babu Banarsi Das University Lucknow

ABSTRACT
Aceclofenac and paracetamol in combination are available as tablet dosage forms in the ratio of 1:5. A simple, reproducible and efficient method for the simultaneous determination of aceclofenac and paracetamol in synthetic mixture was developed. The proposed method is based on the Q-analysis UV Spectrophotometric method. The absorbance maxima of aceclofenac and paracetamol were found to be 275.4 nm and 248 nm, respectively in methanol. In Q-analysis, the isoabsorptive point for both the drugs was found at 266.1 nm. The linearity range lies between 1-35 µg/ml for aceclofenac and 1-15 µg/ml for paracetamol at their respective wavelengths. Both the drugs obey Beer’s law. The recovery studies confirmed the accuracy of the proposed methods.

Lupin Pharmaceuticals, Inc. is the U.S. wholly owned subsidiary of Lupin Limited, which is among the top six pharmaceutical companies in India. Through our sales and marketing headquarters in Baltimore, MD, Lupin Pharmaceuticals, Inc. is dedicated to delivering high-quality, branded and generic medications trusted by healthcare professionals and patients across geographies.

ANSWERS of Previous PharmaQUIZ-4:
1.B   2.B   3.A   4.A   5.C
6.D   7.A   8.C   9.C   10.A
SEE QUESTIONS OF QUIZ - 4

Piramal Healthcare Ltd, a Piramal Group company, is a globally integrated healthcare company that fulfills unmet medical needs across the world. It has a growth track record of above 29% CAGR since 1988. Piramal Healthcare had consolidated revenues of US$ 656 million in FY2009. PHL is currently ranked 4th in the Indian market with a diverse product portfolio spanning several therapeutic areas.

Study Subject(s): Subjects taught at University
Course Level: Undergraduate and Graduate
Scholarship Provider:  ETS
Scholarship can be taken at: US, UK, Canada, Australia and other countries

ANSWERS of Previous PharmaQUIZ-3:

CavinKare- a youthful company fired by ideas, dynamism and professionalism first entered the hair care arena in 1990. The success story began with Chik shampoo, the name which rewrote every rule in the market by popularizing the sachet concept in India.
In this short span of time, CavinKare has not merely taken on the mighty MNC challenge but notched up a stupendous 46% compounded annual growth along the way.

North-Eastern Hill University was set up by an Act of Parliament and notified on 19th July 1973.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

The R&D Division of the company is engaged in herbal drug standardization and evaluation using newer and advanced methods available for standardization of herbal drugs like fluorescence quenching, combination of chromatographic and spectrophotometric methods, biological assays, use of biomarkers in fingerprinting. Immediate requirement to addressed the needs of patented Ayurvedic formulations, Herbal Supplements, Organic Herbs, Pure Herbs, Classical Ayurvedic Products.

About Authors:Kamal Sachdeva*², Preeti Garg¹, Manmohan Singhal², Birendra Srivastava²
1. School of Pharmacy, Suresh Gyan vihar University, Jaipur
2. School of Pharmaceutical sciences,
Jaipur National University,
Jaipur, India

Abstract: The extracts of the stem bark of Jatropha curcas (Family-Euphorbiaceae) were tested for anti-diabetic activity, using blood glucose level in normal fasted rats, glucose tolerance test. Methanol: acetone: water (70:20:10) crude extract of Jatropha curcas at the dose of 100 and 300 mg/kg had shown significant protection and lowered the blood glucose levels to normal in glucose tolerance test. The extract showed a significant anti- diabetic activity comparable with that of glibenclamide. These results indicate that the Jatropha curcas stem bark possess significant anti – diabetic activity.

About Authors: Pratham Rathore ^*[1], Dhaval Patel ^[1], Vipin Rastogi ^[2]
1.  School of Pharmaceutical Sciences,
Jaipur National University, Jaipur -302025, (Rajasthan.), India
2.  Nariender Mohan hospital and heart center,
Ghaziabad, (Uttar Pradesh), India

ABSTRACT: Inpresent study,the current status of nosocomial infection, rate of infection and distribution of infectionwas analysed in patients admitted in MICU of a multispecialty hospital.Clinical data were collected from patients that presented with symptoms of nosocomial infection in MICU. We examined of 128 patients who were admitted in Nariender mohan hospital, Ghaziabad from August 2010 to May 2011. The research approach adopted in the study was a retrospective method. Incidence of nosocomial infections in M.I.C.U patients was 10.93% (14/128 patients). Urinary tract infection (42.85%) was the most frequent; followed by Lower respiratory infection (14.28%), surgical site infection (14.28%), Gastroenteritis (14.28%), Blood stream infection and Meningitis (7.14%). The nosocomial infection was seen more in the 40 to 60 year of age. The male was more prone to nosocomial infections than the female. Nosocomial infections are common in geriatric patients in the MICU setting. More studies are needed to be carried out in Indian population to plan long term strategies for prevention and management of nosocomial infections.

Central Council for Research in Homoeopathy (CCRH) was established as an autonomous organisation in 1978, under the Dept. of AYUSH, Ministry of Health & Family Welfare, Govt. of India. Primarily a research body, CCRH has a multi-dimensional approach to research and its varied research activities include 'Survey, collection and cultivation of medicinal plants', 'Drug standardisation', 'Drug proving', 'Clinical verification' and 'Clinical research'.

The Kerala Public Service Commission is a body created by the Constitution of India.

ANSWERS of Previous PharmaQUIZ-2:

1.C   2.C   3.B   4.A   5.C

6.D   7.D   8.E   9.A   10.B

About Authors:
Priya Pathak, Dr.H.H.Siddiqui*, Mr T.Mehmood
Faculty of pharmacy
Integral University,Lucknow

ABSTRACT
The article is a review on all the methods which have been evolved in recent times for curbing the menace caused by arsenic to our environment and humans. Arsenic poisoning is the most spread problem these days in India,as the main reasons of arsenic poisoning include the wastes being dumped by industries which in turn helps in increasing the amount of arsenic in groundwater. Mostly used method for removal of arsenic is oxidation of As(III) to As(V) and its subsequent removal through adsorption and/or precipitation.Generally alumina is used for adsorption purpose.Many methods have also been evolved for managing the increase of arsenic amount through wastes like Cement Solidification, Dolocrete Encapsulation Technology etc.which have been discussed later in the article. Many low cost technologies are also present like Arsenic removal plant fitted directly with hand pump, Co-precipitation-Sedimentation-Filtration under continuous flow system and use of Domestic filters.These techniques are used in case when large amount of water has to be treated as rest other technologies will become quite costly in this case.Although they cannot help in removing arsenic at large level but can be used in our daily life so that we could control arsenic pollution to some extent.

About Author:
D. J. Kalena^*, C. N. Patel
Department of Quality Assurance,
Shri Sarvajanik Pharmacy College,
Near arvind baug, Mehsana - 384 001, Gujarat, India

ABSTRACT
Combination therapy of Atorvastatin calcium (AT) and Olmesartan medoxomil (OLM) is used for the treatment of coexisting essential hypertension and hyperlipidemia in adult persons. In the present study a simple, precise, rapid, efficient and reproducible reversed?phase high performance liquid chromatography (RP?HPLC) method has been developed for the simultaneous estimation of AT and OLM present in its tablet dosage forms. Chromatographic separations were carried out isocratically at 30°C ± 0.5°C on a Kromasil C18 Column (5 μm, 250mm x 4.60mm) with a mobile phase composed of Methanol: Acetonitrile: Water (pH 3.65) in the ratio of 50:27:23 % v/v at a flow rate of 1.0 ml/min. Detection is carried out using a UV detector at 260 nm. The retention times for AT and OLM were 5.3 ± 0.5 min and 3.4 ± 0.5 min respectively. The linearity range for AT and OLM were found to be 10?60 μg/ml and 20?120μg/ml with correlation coefficient of 0.996 and 0.999 respectively. The %recovery of the proposed method was found in the range of 98.36-100.91 for AT and 99.27-100.99 for OLM. The relative standard deviations for three replicate measurements in three concentrations of standard solution were always less than 2%. The results of the study showed that the proposed RP?HPLC method is simple, rapid, precise and accurate, which may be useful for the routine estimation of AT and OM in bulk drug and in its pharmaceutical dosage form.

October 2011