Skip to main content

 

Clinical courses

 

Clinical research courses

Dendrimers:-A Carrier for oral drug delivery system

About Author
Manish kumar
Hindu College Of Pharmacy, Sonipat
*maggarwal0007@gmail.com

Abstract:
Dendrimers are perfect monodisperse macromolecules(poloymers) with regular and highly branched 3-D structure. Dendrimers have often been referred to as the “Polymer of the 21st century. They are characterized by branch upon branch architecture which are completely different from traditional Polymers. Exceptional feature of a dendrimer includes a high degree of structural symmetry, a density gradient displaying an intra-molecular minimum value and a well defined number of terminal groups. Dendrimers are normally used as carriers for drug delivery especially for oral, ocular and transdermal delivery. Oral drug delivery system are very important to the field of medicine, since most of the common illness are treated via oral route. Encapsulation and conjugation of drug with dendrimers have shown immerse employment for delivery of hydrophobic and labile drugs. Anticancer and antihypertensive drugs are most promising candidates for oral route using dendrimer as carrier. Dendrimers drug delivery system are therefore increasingly viewed as an advantageous for bioactive like drugs and gene. Although dendrimer drug delivery requires attention to certain manufacturing and biological consideration to be successful.

REVIEW ON ONCOLYTIC VIRUS

ABOUT AUTHORS
Ashwini Dhusiya, Ritu Mahajan,
Mahakal Inatitute of Pharmaceutical Studies, ujjain
Madhya Pradesh
.
*ashwinidhusiya@gmail.com

ABSTRACT
Oncolytic virus is a wonderful discovery of 21st century. The basic concept of Oncolytic virus was developed since 1946 but it was not produce its effect properly. Now latest technology and modern biotechnology introduce a very efficient Oncolytic virus. This is a genetically modified virus that can treat various type of cancer with fewer side effects than other treatment of cancer. It follows different mechanism of killing tumor by specifically replication; induction of tissue necrosis factor; activation of immunity and treat incurable cancer even in metastatic stage of cancer so it is also effective in leukemia. Oncolytic virus therapy is undergoing in clinical trial and shows better results.
This article covers brief knowledge of cancer, Virus and Oncolytic virus. It is helpful to understand history, mechanism, benefits and clinical data of Oncolytic virus. And a summary of marketed product ready to launch in near future.

Require Shift Chemist in CGSPCL - 15 vacancies

Chhattisgarh State Power Holding Co. Ltd. invites online applications for the posts of Assistant Engineer (Trainee), Shift Chemist (Trainee) and Junior Engineer (Trainee) in C.S. Power Distribution /Generation/ Transmission

Post: Shift Chemist

Opening Patents - Manager in Piramal Lifesciences

Piramal Life Sciences Limited (PLSL) is an independent research-driven drug company that was recently demerged from Piramal Healthcare Limited (Formerly known as Nicholas Piramal India Limited). PLSL was formerly the NCE R&D division of NPIL. PLSL has state-of-the-art R&D laboratories built over 200,000 square-feet of space in Mumbai, India and over 300 scientists engaged in drug discovery and development.

COMPARATIVE STUDY OF DRUG PRODUCT RECALL REGULATIONS IN USA, UK AND AUSTRALIA AND DRAFT GUIDELINES FOR INDIA

About Authors: 
Bane Singh Rajput*
Research Scholar of Lachoo Memorial College of Science & Technology
Pharmacy Wing, Jodhpur (Raj.)
*bnsingh29@gmail.com

Abstract
Drug product recall is an action taken to withdraw or remove a batch or an entire production run of a drug product from distribution or use and return them to the manufacturer. It is usually done due to the discovery of deficiencies in quality, efficacy or safety in the marketed drug products. Defective drug products related to quality includes adulterated or spurious drugs. Safety and efficacy related recalls include serious adverse reactions and death. Recalls also include drugs prohibited under the law and also those products for which product licenses are suspended/ cancelled. In USA, guidelines for drug product recall are described under 21 CFR Parts 7, 107 and 1270.  In Australia, guidelines for drug product recall are described under section 65F of the Trade Practices Act 1974. Sections 2(2), 4, 5 and 7 of the European Communities Act 1972 and Directive 2001/95/EC on general product safety are followed in UK for drug product recall. In India, references for drug product recalls, complaint and adverse reactions are mentioned in Para 27, 28 of Schedule M and conditions of license for defective product recall in Rule 74(j) and Rule 78(i) of the Drugs and Cosmetics Act, 1940 and Rules there under. But no effective and uniform recall procedure and guidelines are formulated yet in India. This paper presents a comparative study of drug product recall guidelines in USA, UK and Australia. Based on this comparative study suggestions are provided to develop regulatory guidelines for drug product recall in India.

Opportunity to work as TECHNICAL PHARMA OFFICER - R&D by TrueOsis

TrueOsis ever since its inception in 2007 has been involved in providing high quality manpower solutions and services. We have been successful in providing consistent and reliable services to our customers who include BFSI, BPOs, IT Industries, Pharma, Private Manufacturing Enterprises and FMCG Companies.

Post: TECHNICAL PHARMA OFFICER

Work as Business Development Manager in GRACIOUS SERVICES

GRACIOUS SERVICES INC is an outsourcing company based out of Bangalore. We are in the process of foraying into a chain of diagnostic labs across India.

Post: Business Development Manager

Career as Manager-Quality Control (Formulations) in Biocon

AICTE SPONSORED TWO-WEEK FACULTY DEVELOPMENT PROGRAMME @ R. C. Patel Institute of Pharmaceutical Education and Research

The Shirpur Education Society, Shirpur (SES) presently runs 16 highschools, 08 junior colleges, 06 professional Institutes of different disciplines like R. C. Patel Institute of Phannaccutical Education and Research, H. R. Patel Institute of Phannaccutical Education and Research. R. C. Patel Institute of Technology, 1MRD, SeniorCollege, CBSC School etc.

TrueOsis Consultancy invites Medical Representative for Khanna(Punjab)

TrueOsis ever since its inception in 2007 has been involved in providing high quality manpower solutions and services. We have been successful in providing consistent and reliable services to our customers who include BFSI, BPOs, IT Industries, Pharma, Private Manufacturing Enterprises and FMCG Companies.

Post: Medical Representative

Require Medical Representative for fast growing veterinary company

TrueOsis, We believe in planning and preparation, which is the necessary edge for success in any field. We have been constantly preparing ourselves to improve our quality in every sphere. It is due to our constant effort and commitment that we have been able to maintain a healthy relationship with our customers, whose needs are fulfilled to their satisfaction.

A REVIEW ON MÖSSBAUER SPECTROSCOPY

About Authors
Deepak Kumar Shukla*, Nazia Shahid, Vikas Kumar Alaria
Rajasthan Pharmacy College, Bhankrota, Jaipur (Raj.)
*deepakshukla.pharma@gmail.com

Abstract
Over the past several years spectroscopy has become the preeminent technique for determining the structure of organic compounds. The study of recoilless nuclear resonant absorption or fluorescence is more commonly known as Mossbauer spectroscopy. From its first origins in 1957, it has grown rapidly to become one of the most important research methods in solid-state physics and chemistry. Mossbauer spectroscopy uses the nuclear properties to get information regarding the environment surrounding the nucleus. This technique is now valid application in diverse fields, such as solid state physics, metallurgy, chemistry and biochemistry. For example, it is possible to use this method for estimating the iron or tin content in ores, alloys and wasters in a non-destructive manner to concentration down to 0.03 percent in a short time of  the order of 10 minutes. The technique can also detect the relative percentage of  different charged states of the same atom, for example fe2+ and Fe3+ present in the material. This is somewhat difficult to get from any other technique.

(adsbygoogle = window.adsbygoogle || []).push({});

Walk in interview for Pharmacist under the administrative control of CDMO, Kendrapara - 39 posts

Walk in interview for the following Contractual and Regular Paramedical staff under the administrative control of CDMO , Kendrapara will be held at Office of the CDMO, Kendrapara as per following schedule date & time. Interested eligible Candidates may attend the interview along with required documents as mentioned below. The Registration of the candidates will be held from. 10 A.M. to 2 P.M.

Vacancies in All India Institute of Medical Sciences | Require Sr. Biochemist, Sr. Chemist, Chemist, Biochemist

All-India Institute of Medical Sciences was established as an institution of national importance by an Act of Parliament with the objects to develop patterns of teaching in Undergraduate and Post-graduate Medical Education in all its branches so as to demonstrate a high standard of Medical Education in India; to bring together in one place educational facilities of the highest order for the training of personnel in all important branches of health activity; and to attain self-sufficiency in Post-graduate Medical Educati

Vacancy in SPITI for post of Pharmacist

Solapur Power & Industrial Training Institute, Solapur, has been setup by NTPC Ltd. and is being managed by National Power Training Institute, an Autonomous body under Ministry of Power, Govt. of India for development of technical skills through ITI Courses and need based training of power sector personnel in the areas of generation, transmission and distribution.

Require M.Pharm, M.Sc as Senior Research Fellow / Project Assistant II in Centre for Cellular and Molecular Biology

The Centre for Cellular and Molecular Biology (CCMB) is one of the constituent national laboratories of the Council of Scientific & Industrial Research (CSIR) and a premier scientific institute that conducts high quality research in frontier and multi-disciplinary areas of modern biology.

Post: Senior Research Fellow / Project Assistant II

Opportunity for B. Pharma/ M. Pharma Fresher or experience to work from home (full time job) as Pharmaceutical Writer @ Sustain Pharmaceutical - 16 vacancies | ONLY FOR FEMALE CANDIDATES

Sustain Pharmaceutical is basically pharmaceutical-based writing company. Interact with various client staff and faculty and respond to routine inquiries from physicians, client staff. We describes excellence, range, and depth of Pharmaceutical writer's medical writing and product development. The impact of Pharmaceutical writing thought-leader development in worldwide.

Walk - in - Interview for Senior Research Fellow (SRF) and Junior Research Fellow (JRF) in THSTI - 6 posts

The Department of Biotechnology, Ministry of Science & Technology (Government of India) has established the Translational Health Science and Technology Institute (THSTI), an autonomous institution, as a part of the interdisciplinary Health Biotech Science Cluster, in the National Capital Region.

IICB invites applications for Principal Scientist / Sr. Principal Scientist

IICB Institute was established in 1935 as the first non official centre in India for biomedical research and was included within the aegis of CSIR in 1956.
IICB today is engaged in research on diseases of national importance and biological problems of global interest, employing sophisticated state-of-the-art technology in keeping with the rapid and unprecedented momentum that life science research has gained globally over the last 50 years.

Applications are invited for Junior Research Fellow in Indian Veterinary Research Institute

Established in 1889, the Indian Veterinary Research Institute (IVRI) is one of the premier research institutions dedicated to livestock research and development of the region. The institute with faculty strength of more than 275 has a major mandate of research, teaching, consultancy and technology transfer activities. The institute with its long scientific heritage has always enjoyed a certain prestige, a tradition all of its own.

Subscribe to