About Author:
Vivek P. Chavda
Department of Pharmaceutics, B.K. Mody Government Pharmacy College,
Rajkot – 360003, Gujarat (India)
vivek7chavda@gmail.com
Abstract
This technology has just revolutionized the cancer treatment. It is clearly a tool of exceptional value in the functionalization of genes and their validation as potential targets for cancer chemotherapy. Furthermore, a rapidly expanding repertoire of antisense therapy based on the use of antisense oligonucleotides (AONs), small interfering RNAs (siRNAs), micro RNAs (miRNAs), ribozymes and other antisense compounds is being developed to block over expression of key oncogenes and other tumor promoting genes in the treatment of different tumors and many of these nucleic acid-based drugs have demonstrated impressive preclinical and clinical responses.This review highlight some of the cardinal feature of this technology.