Research News

Vera Therapeutics has announced final efficacy results from the Phase 3 ORIGIN 3 study of TRUTAKNA™ (atacicept-vymj), reporting sustained stabilization of kidney function and a reduced risk of kidney disease progression in adults with primary IgA nephropathy (IgAN). The final analysis included 428 patients with primary IgAN who were considered at risk of disease progression.

Cigarette smoke and e-cigarette aerosol may have lasting effects on the body's immune system and blood-forming cells, according to a new study by researchers at the University of California, Irvine. The research found that exposure to cigarette smoke and e-cigarette vapor altered immune responses and affected hematopoiesis, the process through which blood cells are produced. The findings raise concerns about the potential long-term consequences of both conventional smoking and vaping on immune function and the hematopoietic system.

A new study published in Acta Clinica Belgica has found that vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs) can produce substantial tumor shrinkage in patients with metastatic clear-cell renal cell carcinoma (ccRCC) involving the pancreas.