Articles

About Authors:
Yogesh Yaduwanshi*, Gireesh Mehta, Jitendra Shakyawal, Surya Pratap, Sanjay Singh, Mahaveer Kabra
Department of Pharmacology,
Kota College of Pharmacy, Kota,
Rajasthan India
*yogeshyaduwanshi24@gmail.com

Abstract:
Chemicals are an integral part of our daily lives and are responsible for substantially improving them. Yet chemicals can also endanger our health, even our survival. This report focuses on neurotoxic substances, those chemicals that adversely affect the nervous system. Included among such substances are industrial chemicals, pesticides, therapeutic drugs, abused drugs, foods, food additives, cosmetic ingredients, and naturally occurring substances. Whether a substance causes an adverse health effect depends on many factors, including the toxicity of the substance, the extent of exposure, and an individual's age and state of health. Minimizing public health risks requires knowledge about the properties and mechanisms of action of potentially toxic substances to which humans may be exposed. The assessment includes discussion of industrial chemicals, pesticides, therapeutic drugs, substance drugs, foods, food additives, cosmetic ingredients, and such naturally occurring substances as lead and mercury. It does not include radioactive chemicals, nicotine, alcohol, biological and chemical warfare agents, microbial, plant, and animal toxins, and physical agents such as noise.

ABOUT AUTHORS:
¹*Anjali Choba, ²Shikha Attri
¹M.Pharma in pharmacology from shoolini university solan, himachal pradesh
²M.Pharm in pharmaceutical chemistry from lachoo memorial college of science and technology, jodhpur
*anji5057@yahoo.in

ABOUT AUTHORS:
Tara Shankar Basuri^1*, Ishvar Parmar¹, Vishal Modi², Virag Shah³, Niyatee Thakur⁴
SSR College of pharmacy, Silvassa,
U.T of Dadra & Nagar Haveli-396230
*tbasuri@gmail.com

ABSTRACT
Malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on novel synthetic and herbal drugs for malignant melanoma treatment, by a single or combinational agent approach. These molecules are widely used by the oncologists for the treatment of this type of cancer. So this review can help to the public to aware the malignant melanoma and its treatment and novel target for its treatment.

ABOUT AUTHORS:
Jalaram H Thakkar^*, Ashiyana A Mansuri, Chirag Patel, Girish K Jani,
SSR College of Pharmacy,
Silvassa.
^*jay_143143@yahoo.com
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ABSTRACT:
The term Angiogenesis was coined by DR. John Hunter, a British surgeon in 1787. Later professor Judah Folkman gave the idea that growth of tumor depends on their blood supply and a new began research in this new field of therapeutics called ANGIOGENESIS.  Then, the identification of angiogenic growth factors, Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor (FGF) fueled interest in using these factors in inducing therapeutic angiogenesis.^[1] Initially angiogenesis was implicated only in few diseases like cancer, psoriases and arthritis. But, in recent years, it has been evident through a deep research that even excessive, insufficient and abnormal angiogenesis contribute to the pathogenesis of many disorders. Angiogenesis is regulated by a balance between pro- and anti- angiogenic factors. Research shows that angiogenesis and anti angiogenesis has given promising results in treatment of diseases like AIDS, atherosclerosis, ischemic heart disease and Alzheimer’s. In twenty first century, application of angiogenesis in therapeutics may have an impact on disorders similar to that which the discovery of antibiotics had in twentieth century.

I.T.S - The Education Group - established in 1995 under the aegis of Durga Charitable Society, is one of the most reputed education groups in the field of Pharmacy, Dentistry, Engineering, Management, Information Technology, Physiotherapy and Biotechnology. I.T.S has shown incessant growth ever since. The Group has 4 campuses, 8 Institutions and 2D courses. The quality of education is incontrovertibly laudable.

About Author:
Swati Manik
Department of Pharmacognosy,
I.S.F. College of Pharmacy, Moga, Punjab
swatimanik@yahoo.in