Gandhinagar

Applications invited in Government Ayurvedic hospitals/colleges/pharmacies for paramedical staff for five years fixed renumeration by Director, Indian medicine and Homeopathy of system, Block no. 1, 2nd floor, Dr. Jivraj Mehta Bhavan, Gandhinagar, Gujarat.

Posts: Store Keeper, Assistant Pharmacist, B.Pharm Assistant, Lab Technitian

Applications are invited for the JRF position supported by GSBTM in Immunology group with Dr. Reena Rajput. The candidate has to work in the field of immunology and Cell Biology.

Position: JRF (One post)

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Walk–in-interview on 6th March, 2013 for post of JRF under the project “To study the role of Histidine residue(s) in functioning of Arabidopsis cation/H+ Exchanger CAX3 funded by GSBTM, Govt. of Gujarat.

Post: Junior Research Fellow

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Applications are invited for the position of a Junior Research Fellow in DBT-sponsored project: "Study the role of miRNA in regulation of cell death in Parkinson's Disease".

Post: Junior Research Fellow

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Applications are invited for the position of JRF & Lab attendant in GSBTM, Govt. of Gujarat sponsored project: "To study the role of ubiquitin proteosome system and molecular chaperone 70 in the progression of Alzheimer's disease using Drosophila as a model organism."

Post: Junior Research Fellow and Lab Assistant

Applications are invited for the position of Junior Research Fellow (JRF) in DBT sponsored project "Unravelling the cross talk between inflammation and apoptosis: Focusing on regulation of inflammatory mediators and apoptosis in cancer".

Post: Junior Research Fellow

Applications are invited for the position of Junior Research Fellow (JRF) in DBT sponsored project "Unravelling the cross talk between inflammation and apoptosis: Focusing on regulation of inflammatory mediators and apoptosis in cancer".

Post: Junior Research Fellow

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About Authors:
Dhirendra C. Patel^1*, Ritesh B. Patel¹, Gargi B. Patel^2
1Department of Pharmaceutics and Pharmaceutical Technology;
S.K. Patel College of Pharmaceutical Education and Research;
Ganpat University, Kherva, Mehsana, Gujarat, India.
²Pharma Management & Regulatory Affairs,
K.B. Institute of Pharmaceutical Education & Research, Gandhinagar, Gujarat, India.
*dhiren.pharmacy@gmail.com

Abstract:
Oral controlled drug delivery systems represent the most popular form of controlled drug delivery systems for the obvious advantages of oral route of drug administration. However, there are certain conditions for which such a release pattern is not suitable like cardiovascular diseases, Diabetes mellitus, Asthma, Arthritis, Peptic ulcer etc. In such cases pulsatile drug delivery system is used in which release drug on programmed pattern i.e. at appropriate time & at appropriate site of action. Pulsatile Drug Delivery systems are basically time controlled drug delivery systems in which the system controls the lag time independent of environmental factors like pH, enzymes, gastro-intestinal motility, etc. The principle rationale for the use of pulsatile release is for the drugs where a constant drug release, i.e., a zero-order release is not desired. In chronopharmacotherapy drug administration is synchronized with biological rhythms to produce maximal therapeutic effect & minimum harm for the patient. Technically, pulsatile drug delivery systems administered via the oral route could be divided into two distinct types, the time controlled delivery systems and the site-specific delivery systems, thus providing special and temporal delivery. In recent pharmaceutical applications involving pulsatile delivery; multiparticulate dosage forms (e.g. pellets) are gaining much favor over single-unit dosage forms. Various pulsatile technologies have been developed on the basis of methodologies, these includes ACCU-BREAK™, AQUALON,  CODAS®, PRODAS^®, SODAS®, MINITABS^®, DIFFUCAPS®, OROS® etc. Designing of proper pulsatile drug delivery will enhance the patient compliance, optimum drug delivery to the target side & minimizing the undesired effects.

Applications are invited for the position of SRF in ICMR sponsored project: "The study of mitochondrial dynamics during S aureus infection in human epithelial cells" with Dr. Rajesh Singh, Assistant Professor, Cell Biology Group, IIAR.

Post: SRF (One post)