Tramadol

Possible risk of opioid effects in breastfed babies

New Zealand. Medsafe has announced that CARM received a case report where a neonate suffered feeding disorder, somnolence (sleepiness), respiratory disorder and weight decrease while the breastfeeding mother was taking tramadol (Tramal® and Arrow®).

Tramadol is indicated for the relief of moderate to severe pain and is used to help manage pain after a caesarean section.

Small amounts of tramadol and its metabolite, which also helps with pain, are found in breast milk when taken by the mother. Although the amounts of tramadol and its metabolite are too low to cause a problem, there is a risk that the baby’s breathing may be affected or that the baby may be allergic to tramadol or its metabolite.

Medsafe will continue to monitor this issue and will produce updated advice for health-care professionals and consumers as necessary.

Reference : Safety Communications, Medsafe, 9 August 2019