Franco-Indian Pharmaceuticals Pvt. Ltd., a name that stands for quality and innovation, is one of the major players in the Pharmaceutical Industry in India.
Our innovative, value added products improve the quality of life of people and ease their sufferings and help them to enjoy, longer, healthier and more productive lives.

Parenteral Drugs (India) Limited is one of the leading and fastest growing healthcare company, that has constantly followed a path created by its own will, hard work and determination. PDPL is involved in research, production and manufacturing of pharmaceutical products viz. intravenous infusion, tablets, capsules, liquids syrups, injections etc. Established in the year 1983, PDPL has dedicated itself to the manufacturing of the best quality vital life saving drugs at the lowest possible cost.

About Author: Vikas Mahajan* (M.Pharm 1^st  year), Naiyer Shahzad, Sachin Mager
Singhania University,
Pacheri Bari, Rajasthan - 333515

Reference ID: PHARMATUTOR-ART-1054

Abstract
In this study Cytotoxic potential of two Indian medicinal plant extracts were investigated. The invitro cytotoxic potentiality investigated as the ability of these two extracts to inhibit tumour cell line growth with help of MTT & Trypan blue assay. With this investigation we had also focused on angiogenesis. The cell lines studied are MCF7, A549 and DU145 with the methanolic extract of Alium sativum (MEAS) (garlic) and Emblica officinalis (MEEO) (amla). Both drugs are extracted by maceration method. The extract were concentrated & dissolved in DMSO Solvent & stock solution is prepared of conc. 1mg/10 ml. from which different conc. are prepared as 100, 10, 1, 0.1,0 .001 µg/ml. Both plant extracts preapared concentration are exposed in MCF7, A549 & DU145 in 96 well plate in which MTT dye was added later & allow it for 96 hr. after incubation period absorbance was taken in spectrophotometer at 517nm. With same trypan blue also performed & Counting of cell was done on inverted microscope.  Results indicates that the above plant extracts hsowing anticancer and antiangiogenesis activity of Same plant extract were studied on tube formation cell based models also. From this study we can conclude that both drugs possess anticancer activity for MCF7, A549 & DU145 for different concentrations.

About Author: R. C. PATEL, C. K. BHUVA, MR. R. P. SINGH, MR. ABHISHEK DADHICH, MR. ANIL SHARMA.
Department of Quality Assurance, Gyan Vihar School of pharmacy,
Suresh Gyan Vihar University,
Jaipur, Rajasthan, India-302025

Reference ID: PHARMATUTOR-ART-1053

Abstract
Validation has become one of the pharmaceutical industry’s most recognized and discussed subjects. It is a critical success factor in product approval and ongoing commercialization. This article provide brief introduction about the pharmaceutical process validation and its importance according to regulatory provision, also provide the answer of question like why to do, when to do and how to do it. This work is to present an introduction and general overview on process validation of pharmaceutical manufacturing process. Quality is always an imperative prerequisite when we consider any product. Therefore, drugs must be manufactured to the highest quality levels. End-product testing by itself does not guarantee the quality of the product. Quality assurance techniques must be used to build the quality into the product at every step and not just tested for at the end. In pharmaceutical industry, Process Validation performs this task to build the quality into the product because according to ISO 9000:2000, it had proven to be an important tool for quality management of pharmaceuticals.

Biorad Medisys Pvt. Ltd. is an Indian company providing the world with innovative life saving medical devices in the field of Urology, Gastro-enterology, Interventional Radiology and Gynecology. Our organization is committed to satisfying our customer's world wide with quality, cost effective products.

MicroGene has been driven by a clear objective: to bring in medical technology to help people live healthier lives. This objective drives our work. It’s a  commitment to focusing on what matters most: life and the potential it holds when we are feeling our best.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

About Author: Deepali Jaybhaye, Sushilkumar Varma, Amol Gite
Department of Pharmacology, Mahatma Gandhi Mission Hospital,
Aurangabad, Maharashtra – 431001, India.
Vijay Bonde
Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,
Sewagram, Wardha, Maharashtra – 402102, India.

Reference ID: PHARMATUTOR-ART-1052

Abstract
Tectona Grandis linn. is one of the well known Indian herbs. In Ayurveda Tectona grandis stem extract has tocolytic effect. The main syndrome of preterm birth is caused by uterus contractions from excitatory factors. Administration of tocolytic agents is a strategy to prevent the occurrence of preterm births. The aim of this study was to investigate the effects of Tectona grandis stem extract on the contractions of uterine strips isolated from non?pregnant female Wistar rats (250~350 g) prior injected (Before 24 Hrs) Estradiol benzoate. Contractions of the uterus were induced with Oxytocin 0.01 IU. The results compared with stander drugs like Magnesium Sulfate (75 mg), Nifedipine (0.18 mg), and Isoxsuprine (0.18 mg) along with their effect on frog blood vessels, rat and frog heart, skeletal muscle. After seeing these effects we conclude that Tectona grandis stem extract possess the same tocolytic effect as that of standard drugs.

About Author: Imran A. Kayyum. Tadwee1*, Sadhana Shahi1, Mahesh Thube1
Government College of Pharmacy,
Aurangabad, Maharashtra, India

Reference ID: PHARMATUTOR-ART-1051

Abstract
The object of this work is to formulate & observe the effect of HPMC K15 polymer on various parameters of evaluation of carbamazepine nasal mucoadhesive microspheres. The microspheres are prepared by spray drying technique with different formulation composition of HPMC K15. The microspheres obtained are meant for the evaluation for its production yield, particle size, swelling ability, Drug content, encapsulation efficiency and Invitro drug release study. IR, TLC study is performed for drug Polymer interaction study of the optimized batch. Morphology is studied be SEM. The results obtain shows that the release rate of the drug decreases and particle size, production yield, swelling index, encapsulation efficiency, mucoadhesion is increases with increase in drug: polymer ratio. TLC study shows no interaction of Carbamazepine and HPMC. SEM study reveals the encapsulation of drug in the HPMC K15 Polymer. The data obtained after Invitro release study fitted to PCP disso software for mechanism of release & kinetic model. The data also treated with design expert software v 7.1 it shows the model is significant. Overall it shows that the polymer HPMC does not posses any interaction with the carbamazepine and showing controlled drug release behavior.

Tidal was incorporated in the year 1995, with the backbone of a strong professional team with true commitment to healthcare profession.

Shield Healthcare is today a recognized, integrated pharmaceutical company with core competencies in the development and manufacture of Active Pharmaceutical Ingredients (APIs) and Finished Dosage Forms as well as in drug discovery.