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ABOUT AUHTOR
HardikRana*, BhargavVaghasiya, MansiDholakia
Department of Pharmaceutics,
Anand Pharmacy College, Anand, 388 001, Gujarat, India.
*hardikrana1439@gmail.com

ABSTRACT
The objective of present study was to enhance the solubility of poorly soluble drug Ibuprofen using spherical crystallization technique.The potential agglomerates were prepared by addition of different concentrationof polymer selected on the basis of Phase solubility study. Spherical agglomerates were prepared using diethyl ether as bridging liquid by neutralizing technique, spherical agglomeration technique, Quasi emulsion solvent diffusion technique. Spherical agglomerates were evaluated for morphology, production yield, drug content, particle size and dissolution behaviour compared with pure drug.The result of phase solubility studies revealed that there is enhancement of solubility by PEG 4000. Rod shaped crystals of pure drug converted to spherical was confirmed by optical microscopy. The dissolution of agglomerates of optimum batch exhibited 88.24% release compare to 47.18% of pure drug within 60 minute. This study demonstrated that spherical crystallization technique can be consider as a suitable alteration of granulation. Ibuprofen spherical agglomerates can be prepared with PEG 4000. It exhibited excellent physicochemical, solubility, dissolution rate in comparison with pure drug. Among other spherical crystallization technique, QESD proved to be excellent techniquefor enhancement of solubility and dissolution.

K.G. Medical College has contributed immensely in the education and training of thousands of graduate and post-graduates who have brought glory and laurels to their Alma mater by the academic and professional excellence. On 16th September 2002 an Act was passed by the Government of Uttar Pradesh resulting in a major milestone in change in the history of the institution in converting and upgrading it as Chhatrapati Shahuji Maharaj Medical University. On the demand of the general public and more than 40,000 Georgians the world over, teachers and students of the University, the Government of Uttar Pradesh in the last week of October 2003 decided to revert the name of the medical university from C.S.M. Medical University to K.G. Medical University.

Post: Pharmacist

Ind Swift Laboratories is the fatest growing API group . We are having 6+ API Manufacturing Facilities across the globe. We are dealing in regulated market having approvals USFDA, MHRA, TGA.

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ABOUT AUHTOR
Manish Patil*¹, Harsha D Jani¹, Suleman S Khoja², Narmin A Pirani³, Shamim S Khoja^3
1Department of Quality Assurance,
Shivam Pharmaceutical Studies and Research Centre, Anand
Gujarat, India.
²Resource person in pharmaceutical quality assurance and Audit Compliance, Vapi
³Registered Pharmacist, Gujarat, India
*manishpatil3194@gmail.com

ABSTRACT
This review article presents the pharmacology of combined Metformin hydrochloride and Teneligliptin hydrobromide hydrate is effective on type 2 Diabetes Mellitus. Metformin is an antihyperglycemic agent which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Teneligliptin, a third generation Dipeptidyl Peptidase-4 (DPP-4) inhibitor exhibits unique “J shaped” structure with “anchor-lock domain” mechanism which provides potent & long duration of action. The addition of teneligliptin once daily to Metformin was effective and generally well tolerated in Korean patients with type 2 diabetes. The mechanism of Metformin hydrochloride and teneligliptin hydrobromide hydrate is quite different. The main objective of this review article is to provide pharmacological and Analytical information of combination of Metformin hydrochloride and Teneligliptin hydrobromide hydrate to researcher in development of combined dosage form.

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Gujarat Ayurved University was established in 1967 by an act passed by Gujarat State legislative Assembly in 1965. It is the first statutory University of its Kind both at national and international level - exclusively devoted to Ayurvedic studies and Research. This University is administratively linked to Ministry of Health and Family Welfare both at State and Centre-indicating its special status.

Post: Teaching Assistant

Translational Health Science and Technology Institute (THSTI) is an autonomous institute of the Department of Biotechnology (DBT), Ministry of Science & Technology, Government of India. THSTI is a part of the interdisciplinary Biotechnology Science Cluster at Faridabad, Haryana in the National Capital Region (NCR). The institution is designed to be a dynamic enterprise with a mission to conduct innovative translational research and to develop research collaborations across disciplines and professions to translate concepts into tangible products to improve human health.

Post : Dean

CIMS (Care Institute of Medical Sciences) has become the most acclaimed name in health care industry across Gujarat, Rajasthan and Madhya Pradesh.  For CIMS, the patient is the first priority- “PATIENT FIRST ALWAYS”- a motive and mantra imbibed in the culture of CIMS.  With consultant availability 24×7 hosting some of the most renowned names in cardiology, cardiothoracic surgery, onco-surgery etc., CIMS has produced some amazing lifesaving results.

Medley was accredited as ISO - 9001 : 2000 company during the year 2003, by American Quality Assessors (AQA). Medley believes that quality is a continuous process and not an isolated stage in the process.
Medley's strength has also been it's product portfolio which has expanded in response to the market needs. As a strategic move towards success, the company has launched its cadiovascular, anti diabetic and neuropsychiatry products through its highly specialized VAZOKARE division.

Post: Executive - Analytical Development

Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post : Senior Clinical Manager

Applications are invited for the recruitment of one Junior Research Fellow (JRF)/ Senior Research Fellow (SRF) positions to work in a DBT funded project entitled “Genome and Transcriptome Sequencing of aromatic rices from North-Eastern region” for a period of three years.

Post: Junior Research Fellow / Senior Research Fellow

Dr. Ram Manohar Lohia Hospital, formerly known as Willingdon Hospital, was established by the British for their staff and had only 54 beds. After independence, its control was shifted to New Delhi Municipal Committee. In 1954, its control  was again transferred to the Central Government of Independent India.

Post : Pharmacist (Group "C" Non-Gazetted)

Cancer is a leading cause of death worldwide. Apart from the various approaches of treatment, cancer chemotherapy is one of the major therapeutic approaches to combat cancer. However, improvements in the survival rate have been only modest mainly due to presence of Cancer Stem Cells. Today, there is a significant clinical need for novel methods of detection and treatment for cancer stem cells that offers improved sensitivity, specificity and cost-effectiveness.

Post : JRF, SRF

inVentiv Health Clinical, a leader in drug development services, has a global infrastructure, therapeutic expertise, and commitment to quality that is unmatched in the industry. For pharmaceutical, biotechnology, generic drug, and medical device companies of all sizes around the world, inVentiv Health Clinical can help you transform promising ideas into commercial reality.

Post: Sr. Clinical Data Manager

Allergan is a global multi-specialty healthcare company that isfocused on discovering, developing and commercialising innovative pharmaceuticals, biologics and medical devices that enable people to live lifeto its greatest potential – to see more clearly, move more freely, expressthemselves more fully. Our innovative products and market leadership positionsare driven by people with a passion for making a difference.

Post: Territory Manager-Indore (Eyecare) (Job Number: 161759)

The journey of Charak began in the year 1947 with a vision to improve the quality of life by making herbal healthcare available internationally.  Our endeavour is to meticulously research and formulate standardized products of the highest quality. We firmly believe that the customer is of paramount importance and therefore we place customer satisfaction as our supreme priority.  Over the years, Charak has established itself as the foremost international herbal healthcare company, recognised as the bastion of customer well-being with top-quality products and services.

Post : Medical representative - 4 post

Shanthu Technologies is engaged in the business of identifying and recruiting qualified personnel for a variety of technical and non-technical disciplines at both the management and staff levels. Years of experience and attention to detail help make Shanthu Technologies a successful visionary in the recruiting industry. Shanthu Technologies has and continues to demonstrate a record of unparalleled growth and success. We have expanded from a single market over six years ago to become a full service leader in the recruiting field.

SIRO Clinpharm is one of the leading Global Clinical Research Organizations (CROs), offering full scope services conducting clinical trials in the Pharmaceutical, Biotechnology and Medical Devices sectors in compliance with International Standards. We are headquartered in India having global presence in USA, Israel and in Europe at Germany, Czech Republic, Greece, Estonia, Romania, Spain and France.

CHC Healthcare is an industry leader and has set the standard for health care products and service delivery with a commitment to develop technology, talents and infrastructure which helps to improve the service delivery in lessor cost to all its customers. CHC Healthcare is the first cardiac remote monitoring solutions provider in India to develop and deliver 24×7 continuous monitoring, diagnosis and support. CHC Healthcare is the recipient of numerous awards and certifications including Best Service Awards from WCCPGC reflecting its dedication to serve the Healthcare industry and the patients globally.

Post : IT - Head