Applications are invited from eligible candidates for the post of Technical Associate sanctioned by National Coordination Centre (NCC) - Pharmacovigilance Programme of India to work at Pharmacovigilance Centre, Department of Pharmacology, Kasturba Medical College, Manipal.

Name of the post : Technical Associate

Applications are invited for the position of a Project Assistant in DBT-sponsored project: “Characterization of role of miRNA in apoptosis with special focus on mitochondrial specific miRNA” with Dr. Rajesh Singh, Assistant Professor, Cell Biology Group, IIAR.

Position: Project Assistant (One post)

NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consulting, Training and Placement. With our in- depth expertise and rich experience in the field of domestic as well as international level, we have been serving aspiring candidatesand organizations in the most professional way.

A State-of-the-Art manufacturing facilities and has a strong position in the Softgel industry. Company's primary focus has been customizing drug delivery solutions for the healthcare industry. They have world class manufacturing facilities which have been accredited by U.K. MHRA, Australian TGA,WHO GMP, Ministry of Health iz.UAE, Jordan, Kenya, Malaysia, Iran, SriLanka, Vietnam, Thailand etc.),NAFDAC Nigeria & others and a packaging facility in Dubai Free Trade Zone.

At Apollo Health Street, we have a strong tradition and belief that personal satisfaction comes from playing an integral part in an organization. In short, we believe in empowered associates.

Govt. of Himachal Pradesh took up initiative in early seventies to set up a CSIR lab to make prudential use of the natural resources of the region.

Applications are invited from qualified individuals for Research Specialist position, sponsored by the National Institute of Animal Biotechnology (NIAB-DBT) project entitled “Studies on epigenetic regulation during lactation and its impact on milk biosynthesis” (NIAB/CP/107/2012).

Post: Senior Research Fellow

Indegene's scientific and competitive intelligence services lend actionable insights to clients to support their strategic decision making. We provide scientific, clinical, and competitive insights to help align the business development, licensing, clinical development, and marketing activities of our clients to current and future market needs.

D.R. johns Lab. is an integrated pharmaceutical major with diversified competencies in bulk drugs, formulations and drug discovery, with a strong orientation towards the advanced regulated markets. A snow-balling momentum in establishing new facilities both in bulk drugs and formulations for the regulated markets, securing approvals from international regulatory authorities and generating intellectual property has resulted in a strategic transformation in Dr johns Lab’s business profile.

The Swift School of Pharmacy is one amongst the many successful ventures of Swift Group of Colleges which has a reputation for pioneering in pursuit of academic excellence. The pharmaceutical industry is one of the fastest growing sectors with India becoming a destination for pharmaceutical and clinical trials. A career in the field of pharmaceutical sciences therefore holds tremendous promise for opportunities globally.

Applications are invited only through online mode upto 12.04.2012 for Direct Recruitment to the vacancies in the following posts:-

POST: Drugs Inspector, Junior Analyst in the Drugs Testing Laboratory, Phenyle Assistant

About Authors:
YASWANTH ALLAMNENI^1*, PAVAN POTTURI¹, RAJKUMAR NULU², RAVADA RAMESH³, P DAYANANDA CHARY¹, ARUN KALEKAR¹.
¹Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar,Andhra Pradesh, India-509228.
²Research and Development Department, Aurobindo Pharma Ltd., Hyderabad, Andhra Pradesh, India.
³HOD, Dept. of Pharmaceutics, Dr. H.L.T. College of pharmacy, Kengal, Channapatna, Banglore(R).
*yaswanthallamneni@gmail.com

ABSTRACT
The aim of this study was to investigate the influence of superdisintegrants on the dissolution properties of a poorly water-soluble drug from complexes prepared by kneading method. Ketoprofen was employed as a model drug. Solid dispersions prepared by kneading method exhibited higher dissolution rate and DE30 values in each case. Ketoprofen tablets were prepared by direct compression technique using microcrystalline cellulose as a directly compressible vehicle. The formulated tablets were evaluated by different In Process Quality Control tests, content uniformity and in vitro drug release study. The FTIR spectra’s study revealed that there were no interaction between polymers and drug. All the tablets formulated employing solid dispersions in superdisintegrants gave rapid and higher dissolution of Ketoprofen when compared to that of Ketoprofen plain tablets. Ketoprofen dissolution from all the tablets followed first order kinetic with correlation coefficient ‘r’ above 0.9470. All dissolution parameters (k₁, DE₃₀ and T₃₀) indicated rapid and higher dissolution of Ketoprofen from tablets formulated employing its solid dispersions in superdisintegrants when compared to plain tablets.

Healthcare and personal hygiene are evolving like never before. It's to match steps with changing lifestyles; eating habits; work culture; environmental changes and associated ailments or needs.

Karnataka Antibiotics & Pharmaceuticals Ltd., (KAPL) Bangalore is a Government Enterprise. From a modest beginning in 1984, KAPL has grown from strength to strength in the areas of manufacturing and marketing of various life saving and essential drugs. With an ISO accredition from KPMG, Netherlands, KAPL is recognised for its total commitment to quality and services in domestic and international markets. On profit from inception, KAPL facilities are approved by many international clients.

Government of India has set up six new National Institutes of Pharmaceutical Education and Research (NIPERs) under the aegis of Ministry of Chemicals and Fertilizers, Department of Pharmaceuticals, at Rae Bareli, Hajipur, Guwahati, Kolkata, Ahmedabad and Hyderabad. These are presently being run with the help of Mentor Institutes. The Institutes are required to be established on their own.

About Author:
K. Sravan Kumar*
Department of Pharmaceutics,
Seshachala College of Pharmacy,
Puttur-517 583, 
Chittoor (dist), A.P., India
*sravank681@gmail.com

Abstract:
In this study, transdermal patches containing Nimesulide were prepared using different ratios of polyvinylpyrrolidone (PVP) and Hydroxy propyl methyl cellulose (HPMC) by solvent evaporation technique using 10%w/w of dibutyl phthalate incorporated as plasticizer. The drug matrix film of PVP and HPMC was casted on a polyvinylalcohol backing membrane that was previously dried at 60⁰C for 6 hrs. All the prepared formulations were subjected to physical studies (moisture content, moisture uptake, Tensile strength, flatness and Drug content determination), in vitro release studies and in vitro skin permeation studies. The physiochemical compatibility of the drug and the polymers studied by IR spectroscopy have absence of any incompatibility. In vitro permeation studies were performed across  skin using a Franz diffusion cell. Variations in drug release profiles among the formulations studied were observed. Based on a physicochemical and in vitro skin permeation study, formulation F1 (PVP/HPMC, 5:1) and F5 (PVP/HPMC, 1:5) were chosen for further in vivo experiments. The anti inflammatory effect and a sustaining action of Nimesulide from the two transdermal patches selected were studied by inducing paw edema in rats with 1% w/v carrageenan solution. Hence, it can be reasonably concluded that Nimesulide can be formulated into the transdermal matrix type patches to sustain its release characteristics.