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SOLVENTS USAGE IN PHARMACEUTICALS INDUSTRY

About Author:
Balbir Singh Negi
GM Regulatory Affairs
SHAH TC Overseas Private Limited, Delhi, INDIA
22 years of industrial Exp,
M.Sc, MBA, Doctor of Science
.

Abstract:
The usage of solvents in active pharmaceutical ingredients (API) and coating plants are very common in pharmaceutical industry. The organic solvents are mostly used in washing of product, cleaning of equipments and the reaction media for separation and purification. The cost reduction of the API products can be reduced by the distillation of mother liquor after establishing of yield in R &D, pilot plant and then in the commercial plant, the next process step is validation, done with fresh solvent of three consecutive batches and then done with three consecutive batches of recovered solvents from mother liquor. The product cost is mainly reduced by the distillation of product mother liquor or to do more research to reduce the quantity of solvent or manufacturing process without solvent.

Applications invited for Trainee/Assistant Officer PPIC in Akum Drugs & Pharmaceuticals - Freshers may apply

AKUMS DRUGS & PHARMACEUTICALS LTD is one of the most innovative, productive and research based pioneer organization of India having its registered office at Delhi and various plants in Haridwar, Uttrakhand giving employment to more than 2000 people. Akums is engaged in the manufacturing of tablets, capsules, injections, syrups on loan licensing and third party manufacturing basis.

Vacancy in Dr. Reddy's Lab - Invites applications for post of Toxicologist

Dr. Reddy's Laboratories (NYSE: RDY) is an emerging global pharmaceutical company with proven research capabilities. The company is vertically integrated with a presence across the pharmaceutical value chain. It produces finished dosage forms, active pharmaceutical ingredients and biotechnology products and markets them globally, with focus on India, US, Europe and Russia.

Field Scientific Officer-Oncology in Biocon-Fresher

Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation. Biocon together with group companies employs more than 2500 employees with approxmimately Rs 1,000 crore turnover and is expected to grow further during the current financial year.

Require Pharmacy Graduate as Assistant Pharmaceutical Chemist in Goa Public Service Commission

Multiple vacancy in Markfed|Manager(QC), Quality Control Incharge, Dy.General Manager, Chemist, Micro Biologist

One of Asia’s largest Co-operatives, manufacturing, distributing and Marketing a wide range of products: Vanaspati, Fertilizer, Insecticides, Canned food products etc.
Applications are invited from eligible candidates for the recruitment of below mentioned posts accompanied by two passport size photographs of the candidate, copies of the certificates/ testimonials self attested and fee as per proforma appended below. The other details are given as under:-

SELECTIVE ESTROGEN RECEPTOR MODULATORS: ANTIBREAST CANCER AGENTS

About Authors:
Rawat Pinki1*, Rawat Preeti2, Kumar Piyush3 Kanoujia Jovita3, Singh Sangeeta 1
1. Institute of Pharmaceutical Science and Research, Unnao, U.P., India.
2.  L.T.R. College Of Technology, Meerut, U.P., India.
3. Curadev Pharmaceuticals Ltd., Kanpur, U.P., India.

*pnkrawat@gmail.com

Abstract:
Selective estrogen receptor modulators, called SERMs for short, blocks the naturally circulating estrogen in breast tissues and other estrogen-sensitive tissues in the body. Each estrogen receptor has a slightly different structure, depending on the kind of cell it is in. If a SERM binds to a estrogen receptor, there is no site available for estrogen to bind and it can't attach to the cell. SERMs are called "selective" because they bind to particular estrogen receptors. This selective binding action is sometimes called estrogen inhibition, or estrogen suppression.

REGIONAL MEDICAL RESEARCH CENTRE opens for Scientist C

Applications are invited upto 28th July 2012 for one post of Scientist ‘C’ (Organic Chemistry / Natural Product Chemistry) in the Pay Band PB-3 Rs.15600-39100 + Grade Pay Rs. 6600/- at the ICMR's Regional Medical Research Centre, Belgaum.

Post: Scientist C

Applications are invited for M.Pharm/M.Tech/Ph.D as Research Associate in Indian Institute of Science Education and Research - Government of India

Indian Institute of Science Education and Research Bhopal was created in 2008 by the Ministry of Human Resource Development, Government of India. Its mission is to provide quality science education to UG and PG students.

A REVIEW ON: BIOAVAILABILITY AND BIOEQUILANCE

ABOUT AUTHORS:
1 Shashi Kant*,Satinder Kumar, Rajender Kumar,
Research scholar department of pharmacy.
2 Dr. Bharat Prashar
HOD & Associate professor  Department of Pharmaceutical Sciences, Manav Bharti University, Solan (H.P)

* shashi_ranaute@yahoo.in

ABSTRACT:-
In this review article, we discussed about Bioavailability and bioequilance study, bioavailability means rate and extent to which active ingredients absorbed from a drug product and become available at site of action. This article provides the information about important aspect involved in bioequivalence and regulatory requirement for bioequivalence study. The rate or rapidity at which drug is absorbed is important consideration in treatment of acute conditions such as asthma attack in pain. Extent of absorption is of special significance in treatment of chronic conditions like hypertension, epilepsy. In this review we discussed all the factors affecting bioavailability from its dosage form, objective/purpose of bioavailability study, design and evaluation of bioequilance study, methods of assessing of bioavailability and bioequilance etc.

Vacancy for Drugs Inspector in Drugs Control department of KPSC - Fresher

Applications must be submitted online through the official website of the Commission after 'ONE TIME REGISTRATION' .Candidates who have already registered can apply through their profile.

Department : Kerala Drugs Control

Career as Scientist & Senior Scientist in Translational Health Science and Technology Institute an initiative of Department of Biotechnology, Government of India and International AIDS Vaccine Initiative

Translational Health Science and Technology Institute (THSTI) an initiative of Department of Biotechnology, Government of India and International AIDS Vaccine Initiative (IAVI), USA are seeking Principal Investigators for their new joint collaborative program to accelerate and advance HIV vaccine research and development.

Opportunity for M.Sc / B.Pharm / M.Pharm to work as Executive – QA & QC in Himalaya

The Himalaya Drug Company was founded in 1930 by Mr. M. Manal with a clear vision to bring Ayurveda to society in a contemporary form and to unravel the mystery behind the 5,000 year old system of medicine. This included referring to ancient ayurvedic texts, selecting indigenous herbs and subjecting the formulations to modern pharmacological, toxicological and safety tests to create new drugs and therapies.

Require Product executive / Medical representative in Finition Solutions - 10 posts

Finition Solutions is involved in businesses as diverse as HR Services, Information Technology, Manufacturing and Bio (Environmental Solutions).
• HR Services
• Information Technology
• Environmental Solutions

Post: product executive/medical representative

Wanted Production Chemist / Officer / Executive @ Symbiotec Pharmalab

Symbiotec Pharmalab Ltd., a cortico-steroids API manufacturing company based at Indore in Central India is in the business of development, production and marketing of research-based cortico steroids. Symbiotec is manufacturing cortico steroids since the year 1995 and is a WHO –GMP and ISO 9000 : 2000 certified company with a vision to cater to steroids requirement of our pharmaceuticals world.

Works as Manager- QA in Alchemist

Alchemist Group is one of India’s fastest growing publicly traded Conglomerates currently valued at Rs. 100 Billion with over 8,000 employees across India. Today, the Group has transmuted into a Global Corporation with interests in Food Processing, Hotels & Resorts, Restaurants, Road Technologies and Healthcare.

Post: Manager- QA

Urgent Walk in Interview in Venus Remedies for vacancies in QC & ARD(R&D) - Freshers

Venus start each day by focussing on Innovation & Creativity. We make sure that best healthcare is provided to our patients worldwide.
From a humble beginning in 1991, now we are engaged & engrossed in discovering, developing and delivering innovative pharmaceuticals that help patients to alleviate sufferings.

Opening for Kerala Public Service Commission as Pharmacist - 3 posts

The Kerala Public Service Commission is a body created by the Constitution of India.

Career as Project Associate Level -I in Indian Institute of Chemical Biology

Opening for JRF in INDIAN INSTITUTE OF ADVANCED RESEARCH

Applications are invited from CSIR-UGC JRF/ ICMR-JRF/ DBT-JRF/ DST inspired fellows for position of JRF in Immunology

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