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September 2015

 

 

academics

 

Clinical research courses

DIAGNOSIS OF GRANULAR CELL TUMOUR OF THE UPPER LIP USING POLYMER HRP DETECTION SYSTEM

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ABOUT AUTHORS:
1Neeraj Kumar Lohani*, 2Prakash Singh Nainwal
1Institute of Biomedical Education & Research, Mangalayatan University, Aligarh- Uttar Pradesh, India,
2Govt. medical College Haldwani, Nainital Uttrakhand, India
*neerajlohani06@gmail.com

ABSTRACT:
Oral granular cell tumour is a rare soft tissue tumour ofcan develop on any skin or mucosal surface. Granular cell tumors can affect all parts of the body; however, the head and neck areas are affected 45% to 65% of the time. Of the head and neck cases 70% of lesions are located intraorally (tongue, oral mucosa, hard palate). The next most common location that lesions are found in the head and neck area is the larynx(10%).[1] In patients 30% of cases have been reported to occur in the lip, but this presentation in adults is extremely rare. The present study is concerned a case of oral granular cell tumour in a 60 year-old female, located in the upper lip. Histopathological examination revealed granular cells which stained positively for S-100 protein; a finding supportive of a neural origin. A history of trauma was elicited in this case, and the lesion was treated with surgical excision.

(NewsVoir); The Herbalife Family Foundation (HFF), a non-profit organization dedicated to improving the lives of children by helping charitable organizations provide healthy nutrition to children in need, today announced the launch of the third phase of Casa Herbalife program with Smile Foundation, a national development organization that works for underprivileged children and youth in education, healthcare, livelihoods and women’s empowerment. During the third phase unveiled today in Bangalore, the HFF will extend grants to provide nutritional support to 1,000 children across India, through Smile Foundation’s ‘Mission Education’ program.

Cipla Ltd, a global pharmaceutical company which uses cutting edge technology and innovation to meet the everyday needs of all patients, is announced the appointment of Umang Vohra as Global Chief Financial and Strategy Officer and Prabir Jha as Global Chief People Officer effective 1st October 2015.

Creates a leading Global Established Pharmaceutical (GEP) Business
Expected to be immediately accretive to adjusted diluted EPS  upon closing; USD 0.10- USD 0.12 accretion to adjusted diluted EPS expected in first full year after close with additional accretion anticipated thereafter.

Pfizer Inc. announced that it has completed its acquisition of Hospira, Inc.
“We are pleased that Hospira, the world’s leading provider of injectable drugs and infusion technologies and a global leader in biosimilars, is now part of Pfizer. We want to welcome our new Hospira colleagues to Pfizer. We are excited to add their talents and proud of the shared commitment of all Pfizer colleagues to serving patients worldwide,” said Ian Read, chairman and chief executive officer, Pfizer. “We believe that through this transaction, we’ve created value for our shareholders by delivering incremental revenue and expected EPS growth in the near-term by strengthening our GEP business and positioning it for future growth.”

Pfizer’s GEP business now has a leadership position in the large and growing sterile injectables category, with a robust portfolio of both generic and branded products. The global market for generic sterile injectables is estimated to be USD 70 billion in 2020. In addition, GEP has significantly advanced its biosimilars business with a broadened portfolio of marketed products and pipeline assets, which will benefit from Pfizer’s best-in-class capabilities in monoclonal antibody development and manufacturing. The global market for biosimilars is estimated to be approximately USD 20 billion in 2020. The industry-leading medication management systems business, which is now part of GEP, is a complementary business that benefits patients and healthcare systems through improved accuracy and productivity in clinical care. Pfizer is now poised to use its commercial capabilities, global scale, scientific expertise and manufacturing prowess, which now includes two of the largest sterile injectable manufacturing facilities in the world, to maximize the global potential of its enhanced GEP portfolio of sterile injectables, biosimilars and medication management systems.

“Pfizer and Hospira are now one unified team providing patients with access to one of the broadest and most diverse portfolios of difficult-to-manufacture, life-saving sterile injectable products in the industry. Together, we are also a leading global biosimilars company with a robust pipeline, best-in-class development capabilities and extensive real-world commercialization experience. We can also deliver novel capabilities through our medication management systems business,” said John Young, group president, Global Established Pharmaceutical business. “By increasing the number and availability of high-quality generic injectable drugs and biosimilars that we offer our customers, we are strengthening our commitment to improving the health and quality of life of patients around the world with high quality medicines across key therapeutic areas.”


Pfizer continues to expect the transaction to be immediately accretive to adjusted diluted EPS1 upon closing, and accretive by USD 0.10 - 0.12 per share in the first full year after the close, with additional accretion anticipated thereafter. In addition, Pfizer expects the transaction will deliver USD 800 million in annual cost synergies by 2018. Pfizer intends to update its 2015 financial guidance in the coming weeks to incorporate Hospira. The guidance will reflect the anticipated contribution from Hospira operations from the time of the completion of the Hospira merger to Pfizer's fiscal year end, which is November 30, 2015 for Pfizer’s international fiscal year and December 31, 2015 for Pfizer’s U.S. fiscal year.

Hospira, Inc. is now a subsidiary of Pfizer Inc. The combination of local Pfizer and Hospira entities may be pending in various jurisdictions and integration is subject to completion of various local legal and regulatory steps.



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Sun Pharma initiated voluntary recall of multiple lots of Bupropion Hydrochloride Extended-release Tablets USP (SR), 200 mg, 60-count bottle for "failed dissolution specification", while Wockhardt started recalling its Lisinopril Tablets USP, 5 mg and 20 mg for "CGMP violations".

One-year-old infant's ability to group objects according to the names associated with them - as opposed to their appearance alone - offers a glimpse into how their vocabulary will develop by the time they are 18 months, shows a new study. The findings will appear in an upcoming issue of the open access journal Frontiers in Psychology.

Ezetimibe can reduce the cardiovascular problems in diabetes patients, says a new study. The drug achieved greater reductions in LDL cholesterol than statins alone, resulting in lower risks of cardiovascular events in patients with diabetes and the benefits observed in diabetics were greater than in those without diabetes.