March 2013

Hepatitis A, an acute, self-limiting liver infection is transmitted through the fecal oral route by a picovnavirus, hepatitis A Virus(HAV) (1). It is the major cause of acute viral hepatitis in children (2). HAV cause asymptomatic infection in young children and symptomatic infection in adults (3). A study shows symptomatic infection in 4-16% of children as compared to 75-95% of adults (1). The symptoms include jaundice, fever, abdominal pain, malaise, anorexia which resolve after onset within 1-2 months.

ABOUT AUTHORS:
Mr. Kulkarni Sarang*,Birajdar Shivprasad M., Shaikh Parvej H., Dr. Poul B.N
Maharashtra College of Pharmacy, Nilanga, dist. Latur (MS) 413521, India
*sarangkulkarni342@gmail.com

ABSTRACT
Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast disintegrating tablets with improved patient compliance and convenience. Fast disintegrating tablets are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. Fast disintegrating tablets overcome the disadvantages of conventional dosage form especially dysphagia (difficulty in swallowing) in paediatric and geriatric patients. Natural materials have advantages over synthetic ones since they are chemically inert, nontoxic, less expensive, biodegradable and widely available. They can also be modified in different ways to obtain tailor- made materials for drug delivery systems and thus can compete with the available synthetic excipients. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. The natural superdisintegrants can be used instead of synthetic superdisintegrants as they showed equal disintegrating property as that of synthetic agents or dispersible tablets.

SCOPE was established in the year 1999, under the banner of B. R. Nahata Smriti Sansthan in the memory of great social leader, renowned parliamentarian and educationalist, Late "Shri Bhanwarlalji Nahata". The institute is solely dedicated to Noble Profession of Pharmacy. The academic programs have been bench-marked against the best prevailing standards with regular up-gradation.

The Indian Pharmacopoeia Commission (IPC) is an Autonomous Body, set up under the Societies Registration Act, 1860 by the Ministry of Health & Family Welfare primarily with the objective of periodically bringing out new edition of the Indian Pharmacopoeia, National Formulary of India and other related tasks such as preparing, certification and distribution of Reference Substances.

ABOUT AUTHOR:
BINDU.S
ANNAMACHRYA COLLEGE OF PHARMACY,
RAJAMPET,KADAPA Dist, A.P, INDIA.
sirasalabindupharmacy@gmail.com

INTRODUCTION
Rock salt, also known as halite is the naturally occurring crystalline salt. It is the mineral form of sodium chloride or the table salt that we use. However, rock salt does not look like the regular table salt. Instead, it naturally forms in large isometric crystals. Moreover, rock salt can be white like table salt or it can be red, orange, yellow or blue in color. The color of rock salt basically depends on the amount, and the kind of impurities present in it. Along with sodium, rock salt contains many other minerals including, calcium, zinc, iron, magnesium, potassium, copper and several other trace minerals. Like table salt, rock salt too has great many uses. rock salt in massive bags for the purpose of keeping down ice on the roads in the winter.

About Authors:
Chandan bisht^1*, Dr.Jagannath sahoo², Dr.M.Irfan Khan^3
1,2 Shri Ram Murti Smarak college of Eng. & Tech( department of pharmacy) Bareilly.
³ Deccan Healthcare pvt. Ltd. Pantnagar industrial area
*chandanbisht2011@gmail.com

Abstract:
Mouth dissolving tablets (MDT) are useful in patients, such as pediatric, geriatric, bedridden, or developmentally disabled, who may face difficulty in swallowing conventional tablets or capsules and liquid orals or syrup, leading to ineffective therapy, with persistent nausea, sudden episodes of allergic attack, or coughing for those who have an active life style. Over the past three decades, mouth dissolving tablets have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance The objective of this article is to review the development of MDTs, challenges in formulation,  benefit, limitation ,new MDT technologies and evaluation methodologies.

The Indian Pharmacopoeia Commission is an Autonomous Body set up under the Ministry of Health & Family Welfare, Govt. of India primarily with the objectives of regularly updating the Indian Pharmacopoeia by publishing new edition and its addenda, National Formulary of India and other related tasks such as preparing, certification and distribution of reference substances. It also acts as national Coordination Centre of Pharmacovigilance Programme of India.