October 2011

Naprod’s vision is to become a world class player in oncology through excellence in innovation, discovery of new manufacturing processes / drug delivery mechanisms and consistently high quality of production. We commenced operations in 1994 with the inauguration of our ultra-modern facility for the production of generics and formulations for oncology and other therapeutic applications. We are one of the pioneers in India in lyophilization.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India.

Cipla known for its innovative pharmaceutical products backed by latest in technology and creative marketing practices, is enjoying a commanding position among the top pharma companies in the country.
Several specialised therapeutic divisions and promising new products have been launched and many more are in the pipeline.

Akumentis have strong back up of world class manufacturing & R&D facilities. The manufacturing facility is 3rd largest in Asia with WHO GMP, ISO 9001, ISO14001, USFDA & UKHMRA certifications. we have 1000 innovative products in pipeline.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr.

About Author: P. Sai Praveen*, G. Devala Rao, B. Anupama, V. Jagathi
K. V. S. R Siddhartha College of Pharmaceutical Sciences,
Vijayawada - 520 010.

Abstract:
A simple and sensitive spectroflourimetric method has been developed for the estimation of Darifenacin in pure and pharmaceutical dosage forms. Beers law was obeyed in the range of 1 – 5 µg/ml in methanol at an excitation wavelength (λex) of 292nm and an emission wavelength (λem) of 314nm with good correlation coefficient of 0.9995. The limit of detection (LOD) and limit of Quantification (LOQ) for this method are 0.138 and 0.418 µg/ml respectively and the relative standard deviation of intra-day precision was 0.71% and inter-day precision was 1.07%. Stability studies with respect to time and temperature were also carried out. The results obtained were in good agreement with the labelled amounts of the marketed formulations. This method has been statistically evaluated and found to be accurate and precise.

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