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Uttar Pradesh

  • LIPOSOME NOVEL DRUG DELIVERY SYSTEM

    About Authors:
    Dr.Pushpendra Kumar Tripathi(director of RITM(pharmacy), *Shipra srivastava
    Rameshwaram  Institute Of Technology And Management
    Lucknow.
    *shipra.hanny1987@gmail.com

    Abstract:
    The goal of any drug delivery system is spatial placement and temporal delivery of the medicament. Research works are going on to prepare an ideal drug delivery system which satisfies these needs. Researches carried out by ALEC BINGHAM lead to the development of a new drug delivery system called as liposome. Liposomes are small vesicles (_100 nm) composed of various of lipid molecules which build their membrane bilayers. These formulations are mainly composed of phosphatidylcholine (PC) and other constituents such as cholesterol and lipid-conjugated hydrophilic polymers . Liposomes are biodegradable and biocompatible in nature.

  • Multiple vacancies in Central Institute of Medical & Aromatic Plants ( CIMAP)
    Multiple vacancies in Central Institute of Medical & Aromatic Plants ( CIMAP)

  • Work as Professor, Associate Professor, Assistant Professor & Lecturer in pharmacy @ Llyod Group of institutions
    Work as Professor, Associate Professor, Assistant Professor & Lecturer in pharmacy @ Llyod Group of institutions

    The spark for launching professional education (Management & Pharmacy), both at the undergraduate and post-graduate level at Lloyd has come from Academicians and Business Leaders who felt that the current trend in higher education is only limited to Books, Classes and Exams, that needs to be replaced by more meaningful education so that students are mounded to not only become better professionals but also good human beings at a relatively young age..

  • Job as Group Product Manager, Product Specialist, Area Sales Manager & Medical Representives Synokem Pharmaceuticals
    Job as Group Product Manager, Product Specialist, Area Sales Manager & Medical Representives Synokem Pharmaceuticals

    Synokem Pharmaceuticals, founded in 1982 is an emerging pharmaceutical company with proven capabilities in the areas of manufacturing and marketing. It’s among the fast growing pharmaceutical company in India, which has grown from strength to strength and diversified its activities.
    Synokem Pharmaceuticals Ltd., a 100 crore, progressive, 28 years old organization with all India operations requires for its different

  • Government career for Pharmacist, Engineer & other in North Eastern Railway - Total 65 posts
    Government career for Pharmacist, Engineer & other in North Eastern Railway - Total 65 posts

    North Eastern Railway has issued notification against recruitment of 65 various vacancies under Special Recruitment Drive against Physically Handicapped Quota. Eligible candidates may apply through prescribed application format on or before 06-08-2012. Other details like age limit, educational qualification, application fee details, selection process and how to apply are given below

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  • Application for the Post of Manager - Marketing in PharmaSecure PAS India Pvt. Ltd.
    Application for the Post of Manager - Marketing in PharmaSecure PAS India Pvt. Ltd.

    PharmaSecure is a software and technology company based in the US and India with partners located around the world. A leader in pharmaceutical serialisation, authentication, and e-health, PharmaSecure protects trusted products and enhances consumer access to health information and services.

  • Work as Director in National Institute of Nutrition and NJIL&OMD
    Work as Director in National Institute of Nutrition and NJIL&OMD

    National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu.

  • SELECTIVE ESTROGEN RECEPTOR MODULATORS: ANTIBREAST CANCER AGENTS
    SELECTIVE ESTROGEN RECEPTOR MODULATORS: ANTIBREAST CANCER AGENTS

    About Authors:
    Rawat Pinki1*, Rawat Preeti2, Kumar Piyush3 Kanoujia Jovita3, Singh Sangeeta 1
    1. Institute of Pharmaceutical Science and Research, Unnao, U.P., India.
    2.  L.T.R. College Of Technology, Meerut, U.P., India.
    3. Curadev Pharmaceuticals Ltd., Kanpur, U.P., India.

    *pnkrawat@gmail.com

    Abstract:
    Selective estrogen receptor modulators, called SERMs for short, blocks the naturally circulating estrogen in breast tissues and other estrogen-sensitive tissues in the body. Each estrogen receptor has a slightly different structure, depending on the kind of cell it is in. If a SERM binds to a estrogen receptor, there is no site available for estrogen to bind and it can't attach to the cell. SERMs are called "selective" because they bind to particular estrogen receptors. This selective binding action is sometimes called estrogen inhibition, or estrogen suppression.

  • Opportunity for freshers to work in Olefia Biopharma as Marketing Executives - 13 posts
    Opportunity for freshers to work in Olefia Biopharma as Marketing Executives - 13 posts

    Olefia Biopharma Limited, We would like to introduce ourselves as one of the most rapidly emerging FMCG Company in various fields of Pharmaceutical, Cosmetics, Ayurvedics / herbals and biotech.

  • PRONIOSOMAL POWDERED DRUG DELIVERY SYSTEM OF FLURBIPROFEN :FORMULATION AND EVALUATION
    PRONIOSOMAL POWDERED DRUG DELIVERY SYSTEM OF FLURBIPROFEN :FORMULATION AND EVALUATION

    About Authors:
    *Sunil kumar, Amit kumar shahi, Ravi shanker, R. singh, Dr. R. ParthSarthy, Dr S.K. Prajapati
    Kamla Nehru institute of technology and management, Sultanpur.
    Bundelkhand university, Department of pharmacy, Jhansi

    *sunil.sunilpharma.kumar@gmail.com

    ABSTRACT
    The purpose of this research is to design proniosomal powder drug delivery system of flurbiprofen in a trial to overcome the adverse effects associated with oral administration of the drug. Conventional chemotherapy for the treatment of intracellular infection is no more effective due to limited permeation of drug into cell. This can be overcome by the use of vesicular drug delivery system. Encapsulation of a drug in vesicular structure can be predicted to prolong the existence of the drug in the systemic circulation and thus enhance penetration into target tissue and reduce toxicity.Proniosomal powder are generally present in transparent, translucent or white texture, which makes them physically stable during storage and transport. Due to the limited solvent system present, the proniosomes formed were the mixture of many phases of liquid crystal, viz. lamellar, hexagonal and cubic phase liquid crystals.The potential of proniosomes as a transdermal drug delivery system for flurbiprofenwas investigated by encapsulating the drug in various formulations of proniosomal powder composed of various ratios of sorbitan fatty acid esters, cholesterol, prepared by slurry method. The formulated systems were characterized in vitro for size, vesicle count, drug entrapment, drug release profiles and vesicular stability at different storage conditions. Stability studies for proniosomal powder were carried out for 4 weeks. The method of proniosome loading resulted in an encapsulation yield of 30.6 – 75.4%. Proniosomes were characterised by transmission electron microscopy. In vitro studies showed prolonged release of entrapped flurbiprofen. At refrigerated conditions, higher drug retention was observed. It is evident from this study that proniosomes are a promising prolonged delivery system for captopril and have reasonably good stability characteristics.

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