Lloyd Institute of Management and Technology

About Authors:
Mizna Nigarish*, Vandana Arora Sethi
Lloyd Institute of Management and Technology
Plot no.2 knowledge park-2,
Greater Noida-201306 (U.P)
*mnigarish2@gmail.com

ABSTRACT
The present study has been undertaken to prepare fast dissolving tablets of atenolol by direct compression method with a view to enhance patient compliance. The superdisintegrant used in this study was crosspovidone and sucralose as a sweetening agent. A new formulation of atenolol tablet was designed and compressed by direct compressionmethod. Then its physical parameters including hardness, friability, diameter, thickness, disintegration time, dissolution test were performed for evaluation and characterization of this new formulation. It was observed in the result that the tablet formulation F-4 was found to have maximum drug release at the end of 6 minutes and considered as the most effective formulation. It was also concluded that direct compression technique is a useful method for preparing fast dissolving tablets.