Uttarakhand

17 September 2012

REVIEW ON: PULSATILE DRUG DELIVERY SYSTEM

About Authors:
Bhuvnesh^*1, G.Gnanarajan¹, Preeti Kothiyal¹
Department of Pharmacy, Shri Guru Ram Rai Institute of Technology & Science P.O. Box
80, Patel Nagar , Dehradun 248001, Uttarakhand , India¹
*bhuvnesh.grg89@gmail.com

Abstract
Pulsatile drug delivery systems (PDDS) are gaining importance in the field of pharmaceutical technology as these systems deliver the right dose at specific time at a specific site. A pulsatile drug release, where the drug is released rapidly after a well defined lag-time, could be advantageous for many drugs or therapies.A pulse has to be designed in such a way that a complete and rapid drug release is achieved after the lag time so as to match body’s circadian rhythms with the release of drug which increases the efficacy and safety of drugs by proportioning their peak plasma concentrations during the 24 hours in synchrony with biological rhythm. Pulsatile release systems can be classified in multiple-pulse and single-pulse systems. Various techniques are available for the pulsatile delivery like pH dependent systems, time dependent systems, etc. A popular class of single-pulse systems is that of rupturable dosage forms. Advantages of the pulsatile drug delivery system are reduced dose frequency; reduce side effects, drug targeting to specific site like colon and many more. Now in market varies technologies of pulsatile drug delivery system like Pulsincap, Diffucaps etc. are launched by pharmaceutical companies.

16 September 2012

Multiple vacancies in Multani Research Foundation | Require QA Officers, QA Manager, Microbiologists, F&D Scientists, Analytical Scientists - Fresher may also apply

Multani Research Foundation was established with an objective to develop & deliver best Quality Drugs affordable by needed ones based on scientific rationale and knowledge of Ayurveda. To meet its expansion plan in the area of new range of FMCG and Herbal Drugs development required following personnel.

16 July 2012

Applications invited for Trainee/Assistant Officer PPIC in Akum Drugs & Pharmaceuticals - Freshers may apply

AKUMS DRUGS & PHARMACEUTICALS LTD is one of the most innovative, productive and research based pioneer organization of India having its registered office at Delhi and various plants in Haridwar, Uttrakhand giving employment to more than 2000 people. Akums is engaged in the manufacturing of tablets, capsules, injections, syrups on loan licensing and third party manufacturing basis.

25 June 2012

Opportunity for Medical Representatives to work in GOVERNMENT OF INDIA ENTERPRISE - IMPCL

The Company (Manufacturing Ayurvedic and Unani Medicines) having obtained drug licence from licensing authority (G.M.P.

25 June 2012

A REVIEW ARTICLE ON: GENERAL CONSIDERATIONS FOR CLINICAL TRIALS (ICH EFFICACY TOPIC E8) AND MARKETING AUTHORIZATION

About Authors:
Vinay K. Gupta^*, G. Rajan and Preeti Kothiyal
Shree Guru Ram Rai Institute of Technology & Science,
Patel Nagar, Dehradun
*vngupta74@gmail.com

Abstract
The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) is unique in bringing together the regulatory authorities and pharmaceutical industry of Europe, Japan and the US to discuss scientific and technical aspects of drug registration. Since its inception in 1990, ICH has evolved, through its ICH Global Cooperation Group, to respond to the increasingly global face of drug development, so that the benefits of international harmonization for better global health can be realized worldwide. ICH's mission is to achieve greater harmonization to ensure that safe, effective and high quality medicines. This contains four main topic that are Quality, Safety, Efficacy and Multidisplinary. Here we are mainly explain general aspects of clinical trial that are related to ICH E8 and procedure for marketing authorization of new drug substance in India

18 June 2012

Career in Sharon Bio - Medicine Ltd. as Senior Executive - QA (Formulations)

They aim at earning the reputation of being a reliable manufacturer and a force to reckon with in the area of Production of Chemical Intermediates, Bulk Actives and Pharmaceutical Formulations. They aim at being considered a benchmark when it comes to Production efficiency & excellence across the Globe. They see ourselves in the future as contributing to the success of our customers.

16 April 2012

Opening in ZANEKA HEALTH CARE for post of Production Chemist

ZANEKA HEALTH CARE PVT LTD. is manufacturing more than 400 formulations in the form of tablets, capsules, Dry syrup (Beta Lactum & Non Beta lactum), Ointments, Liquid Syrup & Dry Powder Injections (Beta Lactum)
They at ZANEKA believe that if their customer is happy then they are happy. They are committed to deliver high standard of product and develop products with the feedbacks from the customer and the final consumer following the proper WHO GMP guidelines.

19 March 2012

Work as Deputy Production Manager in Bakson Drugs

29 February 2012

Opening for Sr exe / Asst Manager -QA in NAARI - 6 posts

NAARI aspires to be a world leader in the area of female healthcare, providing medical solutions from puberty to menopause. Our aim is to be the world’s first 100% integrated generic female health pharmaceutical company. This implies complete involvement in every step of production, going from plant extract to final dosage forms.

23 January 2012

Career opportunity for Manager / Dy Manager -QA at Naari

NAARI aspires to be a world leader in the area of female healthcare, providing medical solutions from puberty to menopause. Our aim is to be the world’s first 100% integrated generic female health pharmaceutical company. This implies complete involvement in every step of production, going from plant extract to final dosage forms.

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REVIEW ON: PULSATILE DRUG DELIVERY SYSTEM

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