Mathura

About Authors:
Aditya Dixit¹, Gyanendra Kumar Sharma², Devender Pathak^*3
1M. Pharmacy (Pharmaceutical Chemistry)
²Associate Professor (Pharmaceutical chemistry)
³Director, Professor and Head of the Dept. (Pharmaceutical Chemistry)
Rajiv Academy for Pharmacy, Mathura,
Delhi-Mathura Highway, Chhattikara, 281006, India
dev_15@rediffmail.com*, adixit70@gmail.com

ABSTRACT
A traditional but effective method of developing new targets is lead molecule modification, where an existing popular drug from the market is taken as a lead and similar derivatives are synthesized. With the advent of modern techniques conventional methods have lost their gleam but, reactions are still best understood when performed by the conventional techniques. One such endeavor has been made here where indole has been used as a parent moiety and by adding some functional groups some novel indole derivatives were synthesized and screened for their in vitro antitubercular, and anticancer activity. This synthesis of some fresh indole derivatives was done by using various benzaldehyde derivatives and 2-(o-Aminophenyl)indole in acidic condition then with ammonium acetate and isatin in presence of glacial acetic acid.. The structures of newly synthesized compounds were characterized by IR, ¹H NMR, MASS and elemental analysis.Compounds 3h & 3i showed good antitubercular activity and 3d, 3e & 3g showed good anticancer compared to the standard drug.

About Authors:
Kishan Singh *, Krishn Kumar Agrawal
Institute of Pharmaceutical Research GLA University,
Mathura-281403 (U.P.) India.
*kishan.singh575@gmail.com

ABSTRACT
Herbal drugs are traditionally used in various parts of the world to cure different diseases. The Ayurvedic and Siddha medical systems are very famous medical practices in Indian traditional medicines. Over the last few ,researcher have aimed at identifying and validation plant derived substance for the treatment of various disease .similarly it has been already proved that various parts of plants such as leaf, fruits seeds etc.provide heath and nutrition promoting compounds traditional used against various disease. Aegle marmelos have been used in ethno medicine to exploit its’ medicinal properties including astringent, antidiarrheal antidysentric, demulcent, antipyretic, and anti-inflammatory activities. The present review aims to complete medicinal values of Aegle marmelos generated through the research activity using modern scientific approaches and innovative scientific tools.

Olefia Biopharma Limited, We would like to introduce ourselves as one of the most rapidly emerging FMCG Company in various fields of Pharmaceutical, Cosmetics, Ayurvedics / herbals and biotech.

SKS Group of Institutions (SKSgi) marked its expansion in Mathura with the start of Sanjay College of Pharmacy (SCP). SCP was established in the year 2007 and is located right along the Delhi-Agra NH#2, 125 Km from Delhi, 20Km from Mathura and 12Km from Vrindavan. Approved by AICTE - New Delhi, under Ministry of HRD, the Govt. of India.