SUPERDISINTEGRANTS: A REVIEW
About Authors:
Hemant Rathod*, M.P.Khinchi, Dilip Agrawal, Natasha Sharma
*Department of Pharmaceutics
Kota College of Pharmacy,
Kota, Rajasthan, India
*hemant2787@gmail.com
Abstract
Fast dissolving, fast melting, chewable and orally dissolving or disintegrating tablets are solid dosage forms that disintegrate rapidly and dissolve in the mouth without water. These products have staying power in the marketplace because they appeal to consumers and support increased compliance among users as well as provide effective life-cycle management. The principle challenge with orally disintegrating tablets (ODTs) is to develop tablet formulations that deliver rapid disintegration, pleasant mouth feel and high breaking force for tablet robustness. Superdisintegrants affect a range of formulation parameters; including the rate of disintegration, tablet breaking force, and mouth feel i.e. Polyplasdone XL-10 superdisintegrant provides optimal performance in ODT formulations.
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