GPAT-2010

ANSWERS OF GPAT 2010

Q.91 Amitryptyline is synthesized from the following starting material:

Q.81 Triterpenoids are active constituents of

(A) Jaborandi            (B) Rhubarb

(C) Stramonium        (D) Brahmi

Q.82 Tropane alkaloids are NOT present in

Q.71 Which one of the following is a flocculating agent for a negatively charged drug?

(A) Aluminium chloride      (B) Bentonite

(C) Tragacanth             (D) Sodium biphosphate

Q.61 An isosteric replacement for carboxylic acid group is

(A) pyrrole             (B) isoxazole        (C) phenol             (D) tetrazole

Q.51 Sildenafil is used for treatment of one of the following disorders :

(A) Systolic hypertension

(B) Unstable angina

(C) Pulmonary hypertension

(D) Hypertension due to eclampsia

Q.41 In thiazides following substituent is essential for diuretic activity :

(A) Chloro group at position 6             (B) Methyl group at position 2

(C) Sulphamoyl group at position 7     (D) Hydrophobic group at position 3

Q.31 Which one of the following drugs is withdrawn from the market due to torsade de pointes?

(A) Chlorpromazine         (B) Astemizole

(C) Haloperidol            (D) Domperidone

Q.21 Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

(A) Sodium chloride         (B) Mannitol

(C) Starch                       (D) HPMC

Q.ll Aminotransferases usually require the following for their activity :

(A) Niacinamide                               (B)    Vitamin B₁₂