Tamil Nadu

About Authors:
T.R.PARTHASARATHI*, M.VANITHA SRI.
BIOANALYTICAL DEPARTMENT,
QUEST LIFE SCIENCES PVT. LTD, SDF III, MEPZ,
TAMBARAM, CHENNAI- 600 045, INDIA.
*parthu_14@yahoo.co.in

ABSTRACT :
A novel isocratic reverse-phase high performance liquid-chromatography method for determination of asenapine maleate was developed and validated after optimization of various chromatographic conditions. Samples were separated on a waters x-terra C₁₈ (100 mm × 4.6 mm, 3.5 μ) analytical column. The mobile phase used was acetonitrile: 0.1M phosphate buffer (p^H 3.2) 65:35%v/v operated at 30 °C column oven temperature was pumped at a flow rate of 1.0 mL min⁻¹ and the column eluents were monitored at a wavelength of 272 nm. When sample was injected into the Finnigan surveyor high performance liquid-chromatography system through Finnigan surveyor auto-sampler injector, separation was achieved within 5.0 min. The present method demonstrated was validated with the acceptable values for selectivity, linearity (within the expected concentration range (10–50 μg mL⁻¹; r² > 0.999)), recovery (>95%), precision (%RSD < 2.0), sensitivity (limit of detection: 1.85 µg mL⁻¹ and lower limit of quantification: 2.34 µg mL⁻¹), robustness, and ruggedness.

The Department of Botany, Annamalai University is well known renowned department in teaching and research. The department is UGC sponsored and FIST dept with good record of quality research in the field of plant science

POST: JRF (Post 1)

About Authors:
L.Kalaiselvi^1*, Mr.R.Ulaganathan^2
1 B.Pharm, II M.Tech Nanoscience&Technology,
² Assistant Professor, B.Sc, M.Sc., M.Tech
Department of Biotechnology, Udaya school of Engineering,
Nagercoil, Kanyakumari dt.
*klkselvi@gmail.com

ABSTRACT:
Nanoparticle based systems have significant prospective for diagnosis, treatment and prevention of tuberculosis (TB) Gelatin nanoparticle derived from marine sources (fish skin, bone and fins) has been looked upon as a possible alternative to bovine and porcine. Fish gelatin nanoparticle synthesis by two step desolvation method, it was stable nanoparticles and confirm through Scanning electron microscopy (SEM).These nanoparticle were used as carrier for rifampicin. Our aim to develop a Nano particulate carrier of rifampicin for controlled delivery as well as reduced toxicity. In this study, rifampicin loaded fish gelatin nanoparticle was fabricated by an absorption/adsorption method. The effect of several variables on the Nanoparticle’s characteristics was calculated.

The Food Safety and Standards Authority of India (FSSAI) is an autonomous statutory Authority set up under the Food Safety and Standards Act, 2006 for laying down science based standards for articles of food and to regulate their manufacture, storage, distribution, sale and import to ensure availability of safe and wholesome food for human consumption.

About Authors:
Sriharsha Vardhan
SRM College of Pharmacy,
Chennai, Tamil Nadu
sriharshavardhan.51@gmail.com

ABSTRACT
The present study is formulating Rabeprazole modified release beads (Immediate and Time, Pulsatile Release) and to target the release of the drug in intestine and to avoid stability related problems. Preparation of immediate release (IR) Rabeprazole beads has done by drug layering process and barrier coated beads by providing an enteric coating membrane on IR beads. Timed release beads has done by providing a Film coating for IR and lag time coating for TPR (Timed, Pulsatile Release)  on enteric coated beads. Encapsulation Process and evaluation of enteric coated IR and TPR beads has done by physical evaluation and chemical evaluation. Stability studies have done for best quality Rabeprazole IR and TPR enteric coated beads formulations. Based on the results Formulation 3 and Formulation 9 were selected as the best formulation developed for Rabeprazole Dual Drug Release Capsules.

Southern Railway, in its present form, came into existence on 14th April 1951 through the merger of the three state railways namely Madras and Southern Mahratta Railway, the South Indian Railway, and the Mysore state railway.

Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation. Biocon together with group companies employs more than 2500 employees with approxmimately Rs 1,000 crore turnover and is expected to grow further during the current financial year.

Religare Wellness (formerly, Fortis Healthworld) is a pioneering endeavor within India’s healthcare industry putting health solutions on the retail map. As a part of the vision of Fortis Healthcare and Religare Enterprises, Religare Wellness incorporates setting up of a Pan India World Class Retail Network of health stores that would provide comprehensive solutions under one roof.

At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.