Pharmapedia

Google is excited to release TxGemma, a collection of open models designed to improve the efficiency of therapeutic development by leveraging the power of large language models. Developing a new therapeutic is risky, notoriously slow, and can cost billions of dollars. 90% of drug candidates fail beyond phase 1 trials.

Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood production. As reported online March 22, 2017, in Nature, the researchers found that the lungs produced more than half of the platelets – blood components required for the clotting that stanches bleeding – in the mouse circulation.

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library your genome, which totals more than 3 billion base pairs of DNA has to be copied, precisely, from the parent cell to the new daughter cell.

Vinay Kumar Singh. 
Head-Formulation
Kumar Organic Products Research Centre Pvt. Ltd.,
Bengaluru
Email : formulation_krc@kopresearchcentre.net

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion. The DNA-nanoparticle motor uses the "burnt-bridge" Brownian ratchet mechanism. In this type of movement, the motor is being propelled by the degradation (or "burning") of the bonds (or "bridges") it crosses along the substrate, essentially biasing its motion forward.