Pharmapedia

31 March 2025

Google launches TxGemma, entering in Healthcare

Google is excited to release TxGemma, a collection of open models designed to improve the efficiency of therapeutic development by leveraging the power of large language models. Developing a new therapeutic is risky, notoriously slow, and can cost billions of dollars. 90% of drug candidates fail beyond phase 1 trials.

27 March 2025

Surprising New Role for Lungs : Making Blood

Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood production. As reported online March 22, 2017, in Nature, the researchers found that the lungs produced more than half of the platelets – blood components required for the clotting that stanches bleeding – in the mouse circulation.

19 March 2025

Newly identified bacterial protein to help with design of cancer drug delivery system

A previously unknown protein in a family of bacteria found in soil and the human gut microbiome has been discovered – which could help drug delivery in cancer treatment. In a paper published in PNAS, researchers at King’s College London and the University of Washington describe the unique 3D structure of this protein, which is now being used to develop cancer drug delivery systems that can target drugs to tumour sites.

18 March 2025

Managing your diabetes can help prevent associated vision loss

Diabetes can damage multiple parts of the body, including kidneys, nerves and eyes. DRD affects the blood vessels and nerve cells in the retina, resulting in hemorrhages, abnormal blood vessel growth and loss of critical nerve cells.

11 March 2025

Cryo-Electron Microscopy reveals hidden mechanics of DNA Replication, sheds new light on cancer target

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library your genome, which totals more than 3 billion base pairs of DNA has to be copied, precisely, from the parent cell to the new daughter cell.

7 March 2025

Exosomes in Cosmetics

Vinay Kumar Singh.
Head-Formulation
Kumar Organic Products Research Centre Pvt. Ltd.,
Bengaluru
Email : formulation_krc@kopresearchcentre.net

20 February 2025

Dysfunctional B Cells is a new Cancer Immunotherapy Target

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood, known as the tertiary lymphoid structure, where they become frustratingly dysfunctional when in close contact with tumors.

6 February 2025

How to Get a Pharmacy Job in Australia with the OPRA Exam?

Overseas Pharmacist Readiness Assessment, or the OPRA exam, is a single-paper test conducted by the Australian Pharmacy Council. This is a part of the skills assessment process by the APC, which aims to test the competency of global pharmacists before offering them registration in Australia.

22 January 2025

Can DNA-nanoparticle motors get up to speed with motor proteins?

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion. The DNA-nanoparticle motor uses the "burnt-bridge" Brownian ratchet mechanism. In this type of movement, the motor is being propelled by the degradation (or "burning") of the bonds (or "bridges") it crosses along the substrate, essentially biasing its motion forward.