PharmaTutor (May - 2017)
ISSN: 2347 - 7881
(Volume 5, Issue 5)
Received On: 14/02/2017; Accepted On: 23/02/2017; Published On: 01/05/2017
AUTHORS:
Nesar Ahmad*,Zafar Khan, Noorul Hasan, Abdul Basit, Seikh Zohrameena
Department of Pharmacology, Faculty of Pharmacy,
Integral University, Lucknow, India
* nesar50@gmail.com
ABSTRACT:
Stroke is a destructive experience which can result in permanent disability in brain. There is no permanent drug which can improve the blood flow at infracted area and also improve the neurological deficit. Due to the lack of treatments available for stroke, many researchers will investigate the suitable plants or drugs for the treatment of this disease.
How to cite this article: Ahmad N, Khan Z, Hasan N, Basit A, Zohrameena S; Neuroprotective agents, Natural Plant Herbs & Drugs in Ischemic Stroke: A Review; PharmaTutor; 2017; 5(5); 29-36
[ABSTRACT WITH CITATION] [VIEW AS HTML]
REFERENCES:
1. V. L. Feigin, “Stroke in developing countries: can the epidemic be stopped and outcomes improved?” The Lancet Neurology, vol. 6, no. 2, pp. 94–97, 2007.
2. Madl, C., Holzer, M., 2004. Brain function after resuscitation from cardiac arrest. Curr. Opin. Crit. Care 10, 213–217.
3. Choe, S.C., Kim, H.S., Jeong, T.S., Bok, S.H., Park, T.B., 2001. Naringin as an anti-atherogenic effect with the inhibition of intracellular adhesion molecule-1 in hypercholesterolemic rabbits. J. Cardiovasc. Pharmacol. 38, 947–955.
4. Jeon, S.M., Bok, S.H., Jang, M.K., Lee, M.K., Nam, K.T., Park, Y.B., Rhee, S.J., Choi, M.S., 2001. Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits. Life Sci. 69, 2855–2866.
5. K. Baker, C. B. Marcus, K. Huf fman, H. Kruk, B. Malfroy, and S. R. Doctrow, “Synthetic combined superoxide dismu-tase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury,” Journal of Pharmacology and Experimen-tal Therapeutics, vol. 284, no. 1, pp. 215–221, 1998.
6. S. Cho, E.-M. Park, M. Febbraio et al., “T he class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia,” Journal of Neuroscience, vol. 25, no. 10, pp. 2504–2512, 2005.
7. U. Dirnagl, U. Lindauer, A. Them et al., “Global cerebral ischemia in the rat: online monitoring of oxygen free radical production using chemiluminescence in vivo,” Journal of Cere-bral Blood Flow and Metabolism, vol. 15, no. 6, pp. 929–940, 1995.
8. Z. G. Zhang, X. Sun, Q. Z. Zhang, and H. Yang, “Neuroprotec-tive effects of ultra-low molecular- weight heparin oncerebral ischemia/reperfusion injury in rats: involvement of apoptosis, inflammatory reaction and energy metabolism,” International Journal of Molecular Sciences, vol. 14, pp. 1932–1939, 2013.
9. C. N. Oliver, P. E. Starke-Reed, E. R. Stadtman, G. J. Liu, J. M. Carney, and R. A. Floyd, “Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain,” Proceedings of the National Academy of Sciences of the United States of America, vol. 87, no. 13, pp. 5144–5147, 1990.
10. K. A. Youdim, J. P. E. Spencer, H. Schroeter, and C. Rice-Evans, “Dietary flavonoids as potential neuroprotectants,” Biological Chemistry, vol. 383, no. 3-4, pp. 503–519, 2002.
11. J. P. E. Spencer, H. Schroeter, A. J. Crossthwaithe, G. Kuhnle, R. J. Williams, and C. Rice-Evans, “Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts,” Free Radical Biology and Medicine, vol. 31, no. 9, pp. 1139–1146, 2001.
12. P. H. Chan, “Role of oxidants in ischemic brain damage,” Stroke, vol. 27, no. 6, pp. 1124–1129, 1996.
13. C. Rice-Evans, “Flavonoid antioxidants,” Current Medicinal Chemistry, vol. 8, no. 7, pp. 797–807, 2001.
14. Xu, L. and Wu, F., 2015. Cryptanalysis and improvement of a user authentication scheme preserving uniqueness and anonymity for connected health care. Journal of medical systems, 39(2), p.10.
15. Gaire, B.P. and Kim, H., 2014. Neuroprotective effects of Fructus Chebulae extracts on experimental models of cerebral ischemia. Journal of Traditional Chinese Medicine, 34(1), pp.69-75.
16. Ahmed, M.A., El Morsy, E.M. and Ahmed, A.A., 2014. Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats. Life sciences, 110(2), pp.61-69.
17. Jung, Y.S., Park, D.I., Kim, Y.H., Lee, J.H., Seo, P.J., Cheon, J.H., Kang, H.W. and Kim, J.W., 2015. Efficacy and safety of CT‐P13, a biosimilar of infliximab, in patients with inflammatory bowel disease: A retrospective multicenter study. Journal of gastroenterology and hepatology, 30(12), pp.1705-1712.
18. Wang, N., Zhang, Y., Wu, L., Wang, Y., Cao, Y., He, L., Li, X. and Zhao, J., 2014. Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. Neuropharmacology, 79, pp.282-289.
19. Zhang, S., Qi, Y., Xu, Y., Han, X., Peng, J., Liu, K. and Sun, C.K., 2013. Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia–reperfusion injury through suppression of apoptosis and inflammation. Neurochemistry international, 63(5), pp.522-532.
20. Cervantes, M.I., de Oca Balderas, P.M., de Jesús Gutiérrez-Baños, J., Orozco-Ibarra, M., Fernández-Rojas, B., Medina-Campos, O.N., Espinoza-Rojo, M., Ruiz-Tachiquín, M., Ortiz-Plata, A., Salazar, M.I. and Rubio-Osornio, M., 2013. Comparison of antioxidant activity of hydroethanolic fresh and aged garlic extracts and their effects on cerebral ischemia. Food chemistry, 140(1), pp.343-352.
21. Liang, H., Liu, P., Wang, Y., Song, S. and Ji, A., 2011. Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats. Phytomedicine, 18(10), pp.811-818.
22. Mohagheghi, F., Bigdeli, M.R., Rasoulian, B., Hashemi, P. and Pour, M.R., 2011. The neuroprotective effect of olive leaf extract is related to improved blood–brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia. Phytomedicine, 18(2), pp.170-175.
23. Wang, Q., Chen, Z.H. and Ding, Z.X., 2009. Performance of abrasive wear of WC-12Co coatings sprayed by HVOF. Tribology International, 42(7), pp.1046-1051.
24. Kumar, A., Bora, K.S., Jaggi, A.S. and Shri, R., 2016. Comparative evaluation of neuroprotective effect of three varieties of Allium cepa in chronic constriction injury induced neuropathic pain. Thai Journal of Pharmaceutical Sciences (TJPS), 40(1).
25. Hu, Y., Duan, M., Liang, S., Wang, Y. and Feng, Y., 2015. Senkyunolide I protects rat brain against focal cerebral ischemia–reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3. Brain research, 1605, pp.39-48.
26. Cheng, D.T., Mitchell, T.N., Zehir, A., Shah, R.H., Benayed, R., Syed, A., Chandramohan, R., Liu, Z.Y., Won, H.H., Scott, S.N. and Brannon, A.R., 2015. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology. The Journal of Molecular Diagnostics, 17(3), pp.251-264.
27. Park, E., Choi, S.K., Kang, S.W., Pak, Y.K., Lee, G.J., Chung, J.H. and Park, H.K., 2015. Cerebral ischemia-induced mitochondrial changes in a global ischemic rat model by AFM. Biomedicine & Pharmacotherapy, 71, pp.15-20.
28. Shi, Q.J., Wang, H., Liu, Z.X., Fang, S.H., Song, X.M., Lu, Y.B., Zhang, W.P., Sa, X.Y., Ying, H.Z. and Wei, E.Q., 2015. HAMI 3379, a CysLT 2 R antagonist, dose-and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats. Neuroscience, 291, pp.53-69.
29. S. S. Huang, M. C. Tsai, C. L. Chih, L. M. Hung, and S. K. Tsai, “Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia,” Life Sciences, vol. 69, no. 9, pp. 1057–1065, 2001.
30. Sarma, B., Ray, R.S., Mohanty, S.K. and Misra, M., 2014. Synergistic enhancement in the capacitance of nickel and cobalt based mixed oxide supercapacitor prepared by electrodeposition. Applied Surface Science, 300, pp.29-36.
31. Liu, K., Yan, M., Zheng, X. and Yang, Y., 2014. The dynamic detection of NO during the ischemic postconditioning against global cerebral ischemia/reperfusion injury. Nitric Oxide, 38, pp.17-25.
32. Okuyama, S., Morita, M., Miyoshi, K., Nishigawa, Y., Kaji, M., Sawamoto, A., Terugo, T., Toyoda, N., Makihata, N., Amakura, Y. and Yoshimura, M., 2014. 3, 5, 6, 7, 8, 3′, 4′-Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse model. Neurochemistry international, 70, pp.30-38.
33. Al Rouq, F. and El Eter, E., 2014. PPAR-γ activator induces neuroprotection in hypercholesterolemic rats subjected to global cerebral ischemia/reperfusion injury: In vivo and in vitro inhibition of oxidative stress. Experimental gerontology, 51, pp.1-7.
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