After a journey of growth spanning 27 years as Cadila Healthcare Ltd. and the Zydus Group, we have evolved and transformed ourselves in response to the changing times. Our legacy of over 70 years in healthcare and being dedicated to life in all its dimensions is reaffirmed in our new mission, vision and purpose. Unifying ourselves under the Zydus name, Cadila Healthcare Ltd., is renamed as Zydus Lifesciences Ltd.
Post : Research Scientist
Job Description
1. Sound subject knowledge of pharmacokinetics and clinical pharmacology, good understanding on in vitro and in vivo pharmacokinetics properties and data interpretation.
2. Predict the human PK and clinically relevant doses based on non-clinical PK data using an allometry methods.
3. Evaluate novel tools and methodology to improve human PK and dose prediction
4. To establish in vitro-in vivo correlation to understand mechanism of drug disposition.
5. To integrate ADME, in vitro biology and PD results using a modeling and simulation tools. Perform mechanistic PK/PD modeling to build the correlation between PK and PD/efficacy.
6. Establish mathematical or imperial modelling using an in vitro ADME data to predict clinical DDI.
7. Explore an integration of ADME data in mechanistic PBPK modelling and prediction of human DDI.
8. Provide an expert opinion to project team on PK/PD modelling, PBPK modelling and writing a scientific report for regulatory submission.
9. Experience on population PK and PK/PD modelling.
10. Professional experience in pharmacometrics and PK modelling & simulation, proficiency in WinNonlin or Monolix, NONMEM, R and other modelling & simulation tools.
Candidate Profile
PhD or PhD post doc in pharmacokinetics or pharmacology with pharmacometrics subject knowledge or biometry or statistics.
Additional Information
Qualification : PhD or PhD post doc in pharmacokinetics or pharmacology
Experience : 5 years - 15 years
Location : Ahmedabad
End Date : 30th April 2024
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