Articles

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AK MOHIUDDIN
Faculty of Pharmacy, World University of Bangladesh
Dhanmondi, Dhaka, Bangladesh

ABSTRACT Environmental pollution and food contamination are as old as the civilization itself. It is the consequence of the development of civilization, over utilization of nature, industrialization and in fact a price for the progress. It is highly prominent in Dhaka city. Air pollution is mainly due to the vehicle emission, industrial discharge and burning of fossil fuel. The water resource of Dhaka becomes a major health threat due to arsenic contamination, inadequate household/industrial/medical waste disposal and industrial effluent management. Food contamination came from the commercialism of business people who are doing this knowingly to maximize profit. Necessary steps are to be taken to protect the environment for our own existence. This paper reveals chemical pollution and contamination issues of Dhaka city, the capital of Bangladesh.

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Nayan Jain*
Mandsaur Institute of Pharmacy,
Mandsaur, MP, India

ABSTRACT
Sexual dysfunction or sexual disorder is difficulty experienced by a couple or an individual during any stage of a normal sexual activity, including physical pleasure, preference, desire, arousal or orgasm. Sexual arousal disorders were previously known as impotence in men and frigidity in women, though these have now been replaced with less judgmental terms. The causes vary considerably but include a possible decrease in the production of normal estrogen in women or testosterone in both men and women. Causes of dysfunction are aging, fatigue, pregnancy, medications or psychiatric conditions, such as depression and anxiety.

Herbal medicines may cure or prevent certain ailments. However, there are very little recorded data available to support the dose, efficacy, side effects and interactions. Because the safety and efficacy of herbal remedies they are likely to be used then synthetic medicines. The amount of active ingredients in herbals may vary among preparations. Thus, standardization of herbal medicines is required.

ABOUT AUTHORS
Diksha A. Narwade*, Dr. A. N. Aher
Department of Pharmacognosy,
MVP samaj college of pharmacy,
Gangapur road Nashik, Maharastra, India
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ABSTRACT
This paper gives the information about the Annona squamosa Linn. (Family: Annonaceae). Phytochemical and pharmacological studies of medicinal plant were performed. The plant is highly used traditionally for curing diverse diseases and disorders. It is locally known as “Sitaphal'' in Hindi. Macroscopical & microscopical studies of leaves have been studied. The phytochemical studies showed the presence of amino acids, terpenes, lipids, steroids, flavonoids, ascorbic acid, tannins, vitamins and alkaloids. The plant has various pharmacological actions such as insecticidal, purgative, laxatives, astringent, anti-inflammatory, antidiabetic, anti-ulcer, anti-oxidant, antimalarial and antibacterial. The reveiw specifically deals with the phytochemical and folkloric medicinal importance of plant.

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Suleman S. khoja * ¹, Dr. L J. Patel ², Sohil S. Khoja ³, Karim R. Panjwani ³, Jagdish Ray^3
1 PhD. Research Scholar, Ganpat University, Mehesana, Gujarat, India
² Faculty of Pharmacy, Ganpat University, Mehesana, Gujarat, India
³ Resource person, Pharmaceutical Quality Assurance, Audit and Compliance, Vapi, Gujarat, India

ABSTRACT
Good documentation constitutes an essential part of the quality assurance system and is key to operating in compliance with GMP requirements. Documentation requirements of maintaining complete, accurate, truthful and verifiable data in all cGXP documents that are needed to be maintained as per regulatory requirements and various Governmental regulations, laws, rules and statutes/acts. Documentation may exist in a variety of forms, including paper-based, electronic or photographic media. Ensure that the Document should be free from error and during any point if error identify then rectify with proper reason for correcting including sign and date. A system should be in place to indicate special observations and any changes to critical data. GMP Document must have predefined retention period and document must be stored in secure and easy to retrieve or easily available as and when required. Batch Processing and Packaging Instruction must be in place and Contemporaneous entry provision must be available. Instruction and procedure for using equipment; instrument must be clear and specific.  Specification with authorization should be available for analysis of Raw Material and Packing Material, Intermediate and Bulk Product, Finished Product.

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Patil N.B.*, Patil K.B., Wagh M.N., Patil A. A.
Department of Pharmacy,
Ahinsa Institute of pharmacy,
Dondaicha Tal-Shindakheda Dist-Dhule, Maharashtra, India

ABSTRACT
Indapamide is the Thiazide like diuretic drug used in treatment of Hypertension, as well as odema, Heart attack, stroke and heart failure in persons with high blood pressure. It is available in market single component and multicomponent formulations. The article summarizes 57 analytical method including the chromatographic method, LC-MS (Liquid Chromatography-mass spectroscopy), GC-MS (Gas chromatography-mass spectroscopy), spectriflurometric and UV Visible spectrophotometry techniques for estimation of   Indapamide in biological samples, bulk and pharmaceutical formulation.

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ABOUT AUTHOR
AK MOHIUDDIN
Faculty of Pharmacy, World University of Bangladesh

ABSTRACT
After liberation, Bangladesh pharma industry was largely dominated by the import dependent MNCs. On or before 1982 ordinance, 75% of the market was dominated by the MNCs and the rest share was with the other 133 local companies. After NDP formulation and the Drug Control Ordinance, there was a dramatic change of reverse. By 1994, a few pharma companies achieved a tremendous growth and they reinvest their profit for faster return. By next decade, Bangladesh is aiming to 30 world class drug manufacturers to establish strong footstep in global pharma market. Bangladesh, as an LDC got exempted from the obligation of patent and data protection in this arena until 2033. Interestingly, Bangladesh already passed across the LDC landmark to a developing country. So, there’s window of opportunity of more than a decade to grow further from that aspect.

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Kajal V. Kosankar*, Dr. A.N. Aher
MVP samaj college of pharmacy, Gangapur road Nashik, Maharashtra, India

ABSTRACT
Ficus racemosa it belongs to family Moraceae syn. Ficus glomerata Roxb. is the major group of angiosperm (flowering plant). They are widely distributed throughout Asia, Africa, America, Australia, Himalayan ranges, Punjab, Khasia Mountain, Bihar, Orissa, Rajasthan, Deccan, China, Indonesia and Malaysia. Udumber is used from ancient time for treating the many diseases. This tree is used traditionally for public health. It is also called yajnodumbara and grows all over the India at different areas. The common name is ‘Audumbar’ and ‘Umbar’ and used in Unani, Ayurveda and Homeopathy. The leaves tender are used in kalasha prokshana it is sprinkle water to different places from a scared copper mug and the bark is used in Homa. In review macroscopically studies, microscopically studies and chemical constituents are studied on different parts of the plant. Traditional uses and pharmacological uses are described, the extraction of leaves, fruit, stem, bark and latex are done due to this the important constituents are isolated in respective solvent like ethanol, methanol, acetone, petroleum ether, ethyl acetate and water. The more information is described below and the people are moving towards ayurvedic preparations.

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Mir Sahidul Ali¹, Souvik Mukherjee², Debayan Roy², Gargi Pal³, Subhajit Makar*^2
1Department of Chemical & Polymer Engineering, Tripura University (A Central   University), Suryamaninagar, Tripura 799022, India.
²School of Basic & Applied Sciences, Central University of Punjab,Bathinda-155110, Punjab, India.
³ Department of Pharmaceutical Sciences and Technology, NSHM Knowledge Campus, Kolkata- 700053, India.

ABSTRACT: Asparagus racemosus (A. racemosus) is a well-known medicinal plant due its various application in Ayurveda. It contains various type of secondary metabolite active natural products (or ingredients) such as steroids, alkaloids, flavonoids, furan derivatives and essential oils. In the present scenario due to growing catastrophic effect of diseases in human life, researchers are trying to stop synthetic drugs by replacing with herbal drugs. Herbal drug treatments are in general used to provide first-line and public health provider, both to persons abode in faraway areas the place it is the only on hand wellness service, and to people residing in bad areas the place it offers the one cheap relief. In this point of view A. racemosus can show a new path of herbal treatment.

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ABOUT AUTHORS
MUSLEK UDDIN MAZUMDER1*, KISHALAYA DAS2, ABHIJIT DEB CHOUDHURY1, P KHAZEO1
¹department of pharmacy, regional institute of paramedical and nursing sciences, zemabawk 796017, aizawl, mizoram, india.
²department of pharmaceutical sciences, assam university, dargakona 788011, silchar, assam, india.

ABSTRACT
Exposure to sunlight can trigger various biological responses ranging from sun-burn, erythema to skin cancer. Synthetic sunscreen formulations available in market pose variety of adverse effects. Therefore formulation of the herbal sunscreen formulation and evaluation of its sun protection activity is an important aspect in the cosmetic industry. The various herbal agents contain significant sun screen properties which might be useful for formulating herbal creams and lotions. Therefore evaluation of its sun protection activity is an important aspect in the cosmetic industry. The comparative values of the calculated sun protection factor of twelve commonly used vegetables were evaluated using Mansur equation. Hydroalcoholic herbal extracts were obtained and absorbances were recorded between 290-320 nm using UV-Vis spectrophotometer. It was observed that all of the tested herbal extracts showed some UV protection capabilities with hydroalcoholic extract. Hydroalcoholic extract of beet root showed highest SPF i.e. 39.48 while capsicum extract showed lowest i.e. 2.45. These plant herbals can be formulated in the form of cosmetics formulation because of their better acceptability, less irritant nature and also these are less expensive.