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  • BEATING CANCER WITH NATURAL PLANT SOURCES

    ABOUT AUTHORS:
    Mohd. Yaqub khan*, Poonam gupta, Vikaskumar verma, Ashish pathak
    Saroj Institute of Technology & Management,
    Ahimamau, P.O. Arjunganj, Sultanpur Road, Lucknow-226002,
    Uttar Pradesh, India
    *khanishaan16@yahoo.com

    ABSTRACT
    Medicinal plants continue to play a central role in the healthcare system of large proportions of the world’s population. This is particularly true in developing countries, where herbal medicine has a long and uninterrupted history of use. Continuous usage of herbal medicine by a large proportion of the population in the developing countries is largely due to the high cost of Western pharmaceuticals and healthcare. Every year, millions of people are diagnosed with cancer, leading to death in a majority of the cases. Specific part of it is formulated into suitable preparations compressed as tablets or made into pills, used to make infusions, extracts, tinctures, etc., or mixed with excipients to make lotions, ointments, creams, etc. Few herbal drugs are subject to legislative control. The plant based drug discovery resulted mainly in the development of anticancer agents including plants (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan and irinotecan). Beside this there is numerous agents identified from fruits and vegetables can used in anticancer therapy. The agents include curcumin (turmeric), resveratrol (red grapes, peanuts and berries), genistein (soybean), diallyl sulfide, S-allyl cysteine (allium), allicin (garlic), lycopene (tomato), capsaicin (red chilli), diosgenin, 6-gingerol (ginger), ellagic acid (pomegranate), ursolic acid (apple, pears), silymarin (milk thistle), anethol, catechins, eugenol, indole-3-carbinol, limonene, beta carotene, and dietary fiber. In this review active principle derived from natural products are offering a great opportunity to evaluate not only totally new chemical classes of anticancer agents.

  • Aegle marmelos: A phytochemical and phytopharmacological review

    ABOUT AUTHORS
    Junaid Niazi1*, Yogita Bansal2, Narinderpal Kaur3
    1 Asst.Prof., Bahra Institute of Pharmacy, Patiala, India
    2 Assoc. Prof., Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India
    3 Asst. Prof., Baddi University of Emerging Sciences and Technology, Baddi, India

    * niazi.junaid@yahoo.co.in

    ABSTRACT
    Aegle marmelos
    Corr., a deciduous aromatic tree has been recognized in traditional medicine for the treatment of different diseases and ailments of humans like dysentery, fever, diabetes, asthma, heart problems, ophthalmia, haemorrhoids urinary problems etc.  The plant has been reported to contain several phytoconstituents belonging to category of coumarins (like marmenol), alkaloids (like aegeline), glycosides, triterpenoids, anthraquinones, sterols and volatile oils. Several modern scientific studies have authenticated its anti diarrhoeal and gastro protective, anti diabetic, antibacterial, analgesic, anti-inflammatory, antioxidant, anti thyroid, anti histaminic, anti prolifertive and anti fertility activity. Clinical trials of a formulation Diarex (containing A. marmelos has shown positive results patients suffering from diarrhoea and dysentery. This review gives a bird’s eye view mainly on folkloric uses, phytochemistry and pharmacological actions of the plant.

  • ROLE OF HERBAL DRUGS IN PSYCHOSOMATIC DISORDERS

    About Authors:
    Miss Tejaswini Sharma 1*, Mr. Govind Bhandari 2
    1MAHAKAL INSTITUTE OF PHARMACEUTICAL STUDIES, UJJAIN (M.P.)  456010
    2ASSISTANT PROFESSOR,
    MAHAKAL INSTITUTE OF PHARMACEUTICAL STUDIES, UJJAIN (M.P.)  456010
    *Sharma.tejaswini@gmail.com

    ABSTRACT:
    The psychosomatic disorders are variant in nature and to get rid of this problem, we must understand the basics of its causative factors and their effects on sole body.
    Now being herbal drugs are comparatively less toxic and has negligible side effects the use of these drugs on such type of disorders are quite encouraging. So here is the brief study on seldom diseases and their causative factors, and treatment part by herbs accordingly discoursed.

  • EXTRACTION, ESTIMATION AND THIN LAYER CHROMATOGRAPHY OF FEW PLANT METABOLITES: A REVIEW

    ABOUT AUTHOR:
    Dr. Amit Gangwal,
    Associate Professor,
    Smriti college of pharmaceutical education, Indore
    gangwal.amit@gmail.com

    INTRODUCTION
    Plant remains to be the enviable source of molecules of therapeutic significance. Since antiquity, these bio resources have been in use for variety of diseases in different part of the world. Regardless of the type of plant, targeted ailment or other such parameters, the one step which is one of the most important and common is removal of the molecule or fraction or part there of from the plant biomass. Several new methods besides the usual organic solvent extraction have been developed over the last few years for the extraction of primary and secondary metabolites. These are alcohol extraction with various biocompatible solvents, recovery of carboxylic acids and antibiotics with reactive extraction, dissociation extraction, aqueous two-phase extraction, and supercritical and near critical fluid extraction. Extraction and re-extraction processes are integrated into a single step by emulsion liquid membrane and solid supported liquid membrane extractions.

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  • Recent Development in Phytochemical and Pharmacological Investigations of a Devine Medicinal Plant Couroupita guianensis (Anantasajja) – A Review

    About Authors:
    Prashanta kr. Deb1*, Tejendra Bhakta2
    1Dept. of Pharmacy, Tripura University; Suryamaninagar –799022, Agartala, Tripura (w).
    2Regional Institute of Pharmaceutical Science & Technology, Abhoynagar – 799005, Agartala, Tripura (w).
    *shaandeb2010@gmail.com

    INTRODUCTION
    Couroupita guianensis, whose common names include Anantasajja and the Cannonball Tree, is an evergreen tree allied to the Brazil Nut (Bertholletia excelsa), and is native to tropical northern South America and to the southern Caribbean. In India it has been growing for the past two or three thousand years at least, as attested by textual records hence it is possible that it is native to India also.

  • HEPATOPROTECTIVE ACTIVITY A REVIEW

    About Author:
    SOWJANYA GUDUGUNTLA,
    M.Pharmacy, Pharmaceutical Chemistry department
    ANNAMACHRYA COLLEGE OF PHARMACY,
    RAJAMPET, KADAPA Dist, A.P, INDIA.

    Sowjanya09.pharma@gmail.com

  • EVALUATION OF ANTI HYPERLIPIDEMIC ACTIVITY OF GMELINA ARBOREA ON CHOLESTEROL INDUCED HYPELIPIDEMIC RAT MODEL

    About Auhtor:
    Avula Parthasarthi Yadav*,
    Krishna Theja Pharmacy College,
    Jawaharlal Nehru University, Anantapur.
    *parthu298@gmail.com

    1. Introduction
    Currently natural products are gaining popularity to combat various physiological threats including oxidative stress, cardiovascular complexities, cancer insurgence, and immune dysfunction. The use of traditional remedies may be encountered more frequently due to an array of scientific evidence in their favor1.  It has been well established that nutrition plays an important role in the etiology of hyperlipidimia, atherosclerosis and other coronary heart disease (CHD) complications like myocardial infarction1.
    The etiology and pathogencity of coronary heart diseases lie in the casual relationship between the development of atherosclerosis, elevated plasma lipid percentage cholesterol levels in blood and plasma, genetic makeup, endicrinological aberration, immunologic and autonomic factors, blood flow and coagulation2.

  • DIFFERENT PHARMACOLOGICAL ACTIVITY OF INDIAN MEDICINAL PLANTS “ABUTILON”

    ABOUT AUTHORS:
    Girendra Kumar Gautam*1, Chandra Shekhar Singh2, S C Dwivedi3 and G Vidyasagar4
    1,3,4 Suresh Gyan Vihar University, Jaipur, Rajsthan, India
    1 Malhotra College Bhopal, Madhya Pradesh, India.
    2 Shambhunath Insitute of Pharmacy, Allahabad, Uttar Pradesh, India.
    *gk100781@gmail.com

    ABSTRACT
    From last two or three decay, there is a large growth in the sector of plant medicine means herbal medicine. It is due to increase of awareness and knowledge about plant. In India and China, the ratio of this growth is more than any other country of the world.  Interest the usage of various medicinal plants from traditional system of medicine for the treatment of different ailments is also history of India and China. Abutilon is an Indian medicinal genus which has a number of herbs specie,is noted for their medicinal benefits in traditional system of medicine. Abutilonis a large genus of approximately 150 species of broadleaf evergreens in the mallow family, Malvaceae. The genus includes annuals, perennials, shrubs, and small trees from 1–10 m tall, and is found in the tropical and subtropical regions of all continents. Some medicinally important attributes have been assigned to the plants of this species. In sort of this, the present work aim is to find out different pharmacological activity done on this Indian medicinal plant.

  • THE ROLE OF NEW GENERATION PHYTO HORMONES: AN OVERVIEW

    ABOUT AUTHORS:
    Lohithasu Duppala*, Santhosh naidu Matsa, Manikumar Kothakota,

    GITAM Institute of Pharmacy, GITAM University, visakhapatnam, Andhra Pradesh, India-530045.

    lohithasu@gmail.com, +91-9491894432

    ABSTRACT:
    Generally, almost all communication in higher plants was thought to be mediated by the five classes of classical plant hormones  i.e. auxins, cytokinins,  gibberellins, abscisic acid and ethylene. The plant hormone action thus appeared to be basically different from that in animals. This article discusses the general role for new generation of plant hormones includes Brassinosteriods, Salicylic acid. Peptides,Polyaminesand Jasmonates.

  • Garlic (Allium sativum) : Potential Clinical Benefits & Garlic Preparations

    About Authors:
    Sharma Monish*, Kumar Bhupender
    Seth G.L Bihani S. D. College of Technical Education,
    Institute of Pharmaceutical Sciences & Drug Research.
    Sri Ganganagar, Rajasthan (INDIA)

    *monish28sharma@gmail.com

    Introduction :
    The name “Allium sativum” is derived from the Celtic word “all”, meaning burning or stinging, and the Latin “sativum” meaning planted or cultivated. The English word, garlic, is derived from the Anglo-Saxon “gar-leac” or spear plant, referring to its flowering stalk.(Kemper J Kathi.2000)
    Garlic (Allium sativum), a member of the Liliaceae family, is a common food for flavour and spice  and it is one of the herbs most commonly used in modernfolkloric medicine. Garlic was an important medicine to theancient Egyptians as listed in the medical text Codex Ebers(ca.1550 BC) especially for the working class involved in heavy labour because it was an effective remedy for many aliments such as heart problems, headache, bites, worms and tumours. In 1858, Pasteur noted garlic’s antibacterial activity, and it was used as an antiseptic to prevent gangrene during World War I and World War II. (Thomson Martha.et.al.2007, Tattelman Ellen.2005)

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