MEDICATIONS OF QUINAZOLINES AND QUINOXALINES (Qs & Qs): AN OVERVIEW

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ABOUT AUTHORS:
Mayure Vijay kumar*¹, V. Sravanthi¹, Donthineni Kalyan², Sathyanarayana¹, C.P.Meher^1
1Department of Pharmaceutical Chemistry, Maheshwara College of Pharmacy,
²Department of Pharmaceutical Analysis, Saraswathi College of Pharmaceutical Sciences.
Isnapur chitkul ‘X’ road, Patancheru, Hyderabad.
*mayurevijaykumar@gmail.com

ABSTRACT:
The heterocyclic compounds are also called as Hetero-cycle, as majority of the chemical compounds are characterized as hetero-compound due to the joining of atoms with the other compounds. The cyclic part (from Greek kyklos, meaning “circle”), while the prefix hetero- (from Greek heteros, meaning “other” or “different”). Although, Quinazolines and Quinoxalines derivatives are known to possess wide range of activities, the major activity of the compound depend on the position of the appropriate hetero-compound, explained to show the pharmacological activities, the theme of these review is to explain the derivatives of the Q&Q compounds with their medications.

INTRODUCTION:
The heterocyclic compound made up of two fused six-membered a simple aromatic rings, a benzene ring and a pyrimidine ring is named as Quinazoline. Derivatives of quinazoline are called Quinazolines. The Quinoxalines are also known as Benzopyrazine. Here in this hetero compound it is a fusion of benzene ring and a Pyrazine ring. As among these heterocyclic complex compounds the priority of both the compounds are useful in the chemistry studies. The following are the chemistry of Quinazolines and Quinoxalines. Although the compounds are in same structures the difference is in the change in the position of the N compound but shows the almost similar pharmacological activities like the followings antitumor, anti mycobacterial and antidepressant^1,2 etc….;

PROPERTIES OF Qs & Qs COMPOUNDS:

MEDICATIONS: The following are the Quinazolines derivative drugs and there pharmacology uses.

MEDICATIONS: The following are the few Quinoxalines derivative compounds and their pharmacological uses:

CONCLUSION:
The Heterocyclic compounds are the cyclic compound, as it contains the ring made up of more than one kind of atom. Both the Quinazolines and Quinoxalines compound moieties serves as the nucleus for the synthesis of several biologically actives that are useful for the synthesis of the derivatives in their appropriate compound moiety. This review accomplishes the properties and the derivative compounds that are useful to the different types of the un-controllable diseases and explains the latest pharmacological activities and medications of few Q and Q derivative compounds.

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