March 2019

According to local interpretation the name Bhandara is a corruption of Bhanara. Reference to Bhanara is found in an inscription of 1100 A.D.traced at Ratanpur. The district was under regency administration from1818 to 1830. Prior to 1820, the district was administered from Lanji,thereafter the headquarters of the district were shifted from Lanji toBhandara in 1820-21. The area became British Territory in 1853. In 1881 there were only two tahsils viz., Tirora and Sakoli in the district.

National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad (Established in the year 2007) is a prestigious educational institution of national importance under the aegis of Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Government of India, to provide leadership in Pharmaceutical Sciences and other related areas.

With a coastline of about 3,500 miles, inland sources in Rajasthan and Little Rann of Kutch, and the rock salt mines in Mandi, India have possibilities of attaining a high position in salt production among the salt producing countries of the world. As is known, apart from being an indispensable item of food, salt is an important raw material for the manufacture of several heavy chemicals e.g. soda ash, caustic soda and chlorine.

Tweet India Pharmaceuticals Pvt. Ltd. is being headed by Mr. A. K. Arora, who is backed up by his more than 35 years practical and successful experiences of Pharmaceutical Industry and has given his precious and valuable guidance in formulating latest strategies which is followed by many Pharmaceutical Companies, and has been the milestone for the Pharmaceutical Industries. Mr. Arora has created history in establishing many products which are essential and are in the interest of the mankind.

Ansal University was established in 2012 under the Haryana Private Universities Act 2006. Located in the heart of Gurgaon, India’s largest hub of National and Fortune 500 companies, it has seven schools offering programmes in Architecture, Design, Law, Management, Hospitality, Engineering and Health Sciences.  Ansal University has been awarded the National Education Excellence award “Best Private University in Northern India 2017” along with “CSR Excellence in Education” award for 2 consecutive years i.e.

Novo Nordisk is a global healthcare company with 89 years of innovation and leadership in diabetes care. The company also has leading positions within Haemophilia care, growth hormone therapy and hormone replacement therapy. Headquartered in Denmark, Novo Nordisk employs approximately 33,300 employees in 75 countries, and markets its products in more than 190 countries Novo Nordisk’s B shares are listed on NASDAQ OMX Copenhagen (Novo-B).

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ABOUT AUTHORS
P.Mounika^*, Sanjit, Abhishek pandey
Gautham College of Pharmacy
Hebbal, Bengaluru, Karnataka

ABSTRACT:
All active pharmaceutical ingredients are having good therapeutic activity and show poor oral bioavailability , because of poor solubility .The present study is to investigate to improve the solubility of Felodipine using different carriers and different methods of preparation of techniques to identify that which carrier and suitable method of preparation. All formulation are evaluated for hardness, friability, drug content uniformity, and in vitro dissolution studies. Among all the formulations three formulation shows good drug release and the formulation with direct compression method shows good drug release compared to other formulation among all the formulation Polyvinylpyrrolidone (PVP) with direct compression is considered as ideal formulation from the study.