Skip to main content

May 2018

 

 

academics

 

Clinical research courses

ORODISPERSIBLE LIQUISOLID COMPACTS: A NOVEL APPROACH TO ENHANCE SOLUBILITY AND BIOAVAILABILITY

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
VINOTH KUMAR P 1,
*RAJALAKSHMI A.N.1, STEPHEN P2
1Department of Pharmaceutics, College Oof Pharmacy, Mother Theresa Postgraduate And Research Institute of Health Sciences, Puducherry-6, India
1 Department of Pharmaceutics, College of Pharmacy, Mother Theresa Postgraduate And Research Institute of Health Sciences, Puducherry-6
, India
2 Formulation Research and Development, Sai Mirra Innopharm Pvt Ltd., Chennai, India

*ocusertraji@gmail.com

ABSTRACT:
Orodispersible liquisolid system is the combination of liquisolid technique and orodispersible system. The poor dissolution rate of water insoluble drug is a major drawback for the development of pharmaceutical dosage forms. The oral absorption of drug is most often controlled by dissolution in the gastrointestinal tract. Liquisolid system has been used to enhance dissolution rate of poorly water-soluble drugs. Orodispersible tablets are given in order to provide fast action by disperse in the mouth, without the need of water and make them compliance for paediatric and geriatric patients and to bypass the liver metabolism.

Growth In The Pharmaceuticals Market

The global pharma market was worth $934.8 billion in 2017 and will reach $1170 billion in 2021, growing at 5.8%, a report from The Business Research Company shows. This is an accelerated pace compared to 5.2% for the years before 2017, but is slower than the other two large healthcare segments, medical equipment and healthcare services. Healthcare as a whole is growing at over 7% year on year.

The U.S. Food and Drug Administration  approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults. While Lucemyra may lessen the severity of withdrawal symptoms, it may not completely prevent them and is only approved for treatment for up to 14 days.

The U.S. Food and Drug Administration approved Retacrit (epoetin alfa-epbx) as a biosimilar to Epogen/Procrit (epoetin alfa) for the treatment of anemia caused by chronic kidney disease, chemotherapy, or use of zidovudine in patients with HIV infection. Retacrit is also approved for use before and after surgery to reduce the chance that red blood cell transfusions will be needed because of blood loss during surgery.

ICMR invites Ph.D, M.Pharm, M.Sc to work in Division of epidemiology and communicable diseases as Consultants | Emoluments upto Rs 70,000/- pm

The Indian Council of Medical Research (ICMR), New Delhi, the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest medical research bodies in the world.

The Govt, of India through Indian Council of Medical Research (ICMR) has initiated its flagship program by establishing an "Indian TB Research Consortium" to advance technology and product development by harnessing interdisciplinary expertise and regional complementary strengths and focus on building and strengthening scientific capabilities and generating a better understanding to aid in accelerating the development of new diagnostics, new & improved vaccines and Immunotherapies, drugs for TB.

Job openings for Junior Scientific Officer/ Chief Chemist/ Research Officer at MPSC - Government Jobs | 13 posts

Maharashtra Public Service Commission (MPSC) is a Constitutional Body established Under Article 315 of Constitution of India which provides a smooth and efficient functioning of the Government of Maharashtra (GoM) by providing suitable candidates for various Government posts and advise them on various service matters like formulation of Recruitment Rules (RR), advise on promotions, transfers and disciplinary actions etc. As per Article 320 of the Constitution of India, MPSC.

Post : Junior Scientific Officer/ Chief Chemist/ Research Officer, G.S.S., Group-B

Online applications are invited for Pharmacist at KPSC | Government Jobs

The Kerala Public Service Commission is a body created by the Constitution of India. The Commission advise the Government on all matters relating to civil services referred to it under Article 320 (3) of the Constitution and publish notifications inviting applications for selection to various posts as per the requisitions of the appointing authorities, conduct written test and/or practical tests, physical efficiency test and interview, prepare ranked list based on the performance of the candidates and advise candidates for appointment strictly based on their merit and observing the rules of reservation as and when vacancies are reported.

Post : Pharmacist Grade II

Vacancy for M.Pharm, M.Sc as Project Assistant at BioNest, Panjab University

One of the oldest Universities in India, the Panjab University (PU) initiated at Lahore in 1882, has a long tradition of pursuing excellence in teaching and research in science and technology, humanities, social sciences, performing arts and sports. The University supports excellence and innovation in academic programmes, promotes excellence in research, scholarship and teaching. The University is committed to attract and support the best students and faculty, who excel at teaching and research. In independent India, Panjab University with its Campus at Chandigarh and nearly two hundred colleges in Punjab state and Chandigarh U.T., has served various societal needs with distinction. The glorious traditions of the University established during the period of more than 133 years of its long service to the nation since its inception are a source of inspiration for the present generation of faculty members and students.

Post : Project Assistant

Opportunity for Research Assistant at Apotex | Ph.D, M.Pharm, M.Sc

Apotex is a proudly Canadian, global pharmaceutical company that produces high-quality, affordable medicines (both generic and innovative pharmaceuticals) for patients around the world. We are the 7th largest generic pharmaceutical company globally with more than 12,000 employees and estimated sales of approximately $3 billion. Our fully integrated operation is comprised of four lines of business: Global Generics; Apobiologix; Global Active Pharmaceutical Ingredients (API); and ApoPharma (Innovative Products). With our worldwide manufacturing sites, Apotex can produce up to 24 billion dosages per year. We produce 300 medicines in 4,000 dosages and formats that are exported to 115 countries. Apotex will spend $2 billion over the next 10 years on research and development.

Post : Research Assistant