ORODISPERSIBLE LIQUISOLID COMPACTS: A NOVEL APPROACH TO ENHANCE SOLUBILITY AND BIOAVAILABILITY
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ABOUT AUTHORS
VINOTH KUMAR P 1, *RAJALAKSHMI A.N.1, STEPHEN P2
1Department of Pharmaceutics, College Oof Pharmacy, Mother Theresa Postgraduate And Research Institute of Health Sciences, Puducherry-6, India
1 Department of Pharmaceutics, College of Pharmacy, Mother Theresa Postgraduate And Research Institute of Health Sciences, Puducherry-6, India
2 Formulation Research and Development, Sai Mirra Innopharm Pvt Ltd., Chennai, India
*ocusertraji@gmail.com
ABSTRACT:
Orodispersible liquisolid system is the combination of liquisolid technique and orodispersible system. The poor dissolution rate of water insoluble drug is a major drawback for the development of pharmaceutical dosage forms. The oral absorption of drug is most often controlled by dissolution in the gastrointestinal tract. Liquisolid system has been used to enhance dissolution rate of poorly water-soluble drugs. Orodispersible tablets are given in order to provide fast action by disperse in the mouth, without the need of water and make them compliance for paediatric and geriatric patients and to bypass the liver metabolism.