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March 2016

 

 

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Clinical research courses

Walk in interview for Trainee (35 Posts) in Excelra Knowledge Solutions Pvt. Ltd. | B.Pharm, M.Pharm/M.Sc

We are looking for energetic and talented Job aspirants for our Informatics Services, Hyderabad.

Post: Trainee

Vacancy for CRA/Trainee Clinical Research Associate in Novo Nordisk

Sangamo BioSciences, Inc. announced the presentation of new preclinical data in disease models from its In Vivo Protein Replacement Platform™ (IVPRP) programs for MPS I (Hurler syndrome) and MPS II (Hunter syndrome). The data demonstrate that the Company's IVPRP approach enabled stable production of therapeutic levels of replacement enzyme from the liver into the circulation and secondary tissues, including the brain, resulting in significant reduction in biomarkers of the disease and, importantly, statistically significant improvements in cognitive function in treated animals.

Work as Project Leader - Senior Procurement and Supply Management Expert in Swiss Tropical and Public Health Institute

The Swiss Tropical and Public Health Institute is a public institution with the mandate to contribute to the improvement of the health of populations internationally and nationally through excellence in research, services, and teaching and training. The Swiss Centre for International Health (SCIH) of the Swiss TPH conducts consultancy, project management, training and applied research work in international and global health. The department is seeking applications for the following new position:

Post: Project Leader-Senior Procurement and Supply Management Expert

Work as Product Specialist (Personal Hygiene) at HLL Lifecare Limited - Mini Ratna Company of Govt. of India

HLL Lifecare Limited is a Mini Ratna Company of Govt. of India under the Ministry of Health & Family Welfare. HLL, a schedule B Public Sector Enterprise is today a multi product, multi unit organization addressing various public health challenges. The company with five manufacturing units and marketing offices throughout the country is engaged in the manufacturing and marketing of a wide range of contraceptives and healthcare products. The company has also ventured into Infrastructure Development, Procurement & Consultancy Services, setting up of Life Spring Hospitals, Women's Health Pharma Division and setting up of Diagnostic Centres.

Open campus recruitment drive for B.Pharm students at Truba Institute of Pharmacy

Truba Institute of Pharmacy, Bhopal is organizing an Open campus recruitment drive for B.Pharm students (2015 & 2016) to be placed in marketing division of five Leading pharmaceutical companies (MNC's) on 11.03.2016 & 13.03.2016.

Work as Quality Assurance Executive in Pharma Client of Nextus Solutions

Nextus is a dynamic organization offering Strategic Management & HR Consulting Solutions. We offer a range of services covering Business Consultancy, Communication Planning, Recruitment & Training. With a focused Pharmaceutical & Healthcare Industry Practice, Nextus is one of fastest growing Strategic Business Consultancy companies in India, with comprehensive Recruitment & Training solutions. We bring deep, functional expertise to focus on client’s critical issues and opportunities. Our systematic and result-oriented approach helps our clients achieve their goals in cost-effective and timely manner.

AN ISOCRATIC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF RABEPRAZOLE AND MOSAPRIDE IN TABLET DOSAGE FORMS BY USING RP-HPLC

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
S. Ashutosh Kumar*, Manidipa Debnath, Venugopal Padala,
Department of Pharmaceutical Analysis and Quality Assurance,
A.K.R.G College of Pharmacy, Nallajerla, West Godavari, A.P
*ashu.mpharm2007@gmail.com

ABSTRACT
Objective:
The present work was undertaken with the aim to develop and validate a rapid and consistent RP-HPLC method in which the peaks will be appear with short period of time as per ICH Guidelines.
Method: The HPLC separation was achieved on an Inertsil-C18 ODS column (250 X 4.6 mm; 5 µ) column in an Isocratic Mode. The mobile phase composed of Methanol [HPLC Grade] (55 %) and Buffer (45 %) [pH 4.0 adjusted with triethylamine]. The flow rate was monitored at 1.0 mL/min. The wavelength was selected for the detection was 276 nm.
Results:The retention times found for rabeprazole and mosapride was 2.946 and 4.186 min respectively. The % recovery was 99.98- 100.03 for rabeprazole and 99.97 - 100.02 for mosapride. The linearity was established in the range of 20-80 µg/mL for both rabeprazole and mosapride. The LOD for rabeprazole and mosapride were 0.01 and 0.035 µg/mL respectively. The LOQ for rabeprazole and mosapride were 0.032and 0.11 µg/mL respectively.
Conclusion:The proposed method was adequate sensitive, reproducible, and specific for the determination of rabeprazole and mosapride in bulk as well as in tablet dosage forms.