September 2012

About Authors:
Rajender Kumar^1*,Dr.Sukhbir L.Khokara²,
¹Department of Pharmacy, Manav Bharti University, Solan (H.P.) 173229
²Institute of pharmaceutical sciences, Kurukshetra University,
Kurukshetra, Harayana-136119
*rajkaushal13@gmail.com

ABSTRACT
Butenolides (furanones) consist of unsaturated γ- lactone which occur in plants as glycosides. There is a group of steroids which contain α,β unsaturated butenolide ring in the side chain such steroids are known as cardenolides. The  presence of γ - lactone ring contain natural products like Goniobutenolides A & B ,Digitoxigenin and  lignans. These compound have biological properties like antibiotic, antitumor, anticonvulsant, antimicrobial and medicinal uses like fungicides, bactericides and allergic inhibitor.

About Author:
Krishn Kumar Agrawal*, Jeetendra Kumar Gupta, Anju Verma, Kishan Singh
Institute of Pharmaceutical Research,
GLA University 17-Km. stone, NH-2 Mathura-Delhi Highway,
P.O. Chaumuhan, Mathura-281406 (U.P.) India
*krishn.agrawal@rediffmail.com

Abstract
The objective of the present study to investigate the anthelmintic activity of aqueous and ethanolic extract of flower of Hibiscus rosa-sinensis L. (family: Malvaceae) against Indian earthworms (Pheretima posthuma). The preliminary phytochemical screening of Hibiscus rosa-sinensis showed the presence of sterols, glycosides, alkaloids, proteins, mucilage and flavonoids. Various standards such as Piperazine citrate, Albendazole and Pyrantel pamoate at concentration of 20mg/ml were used to compare anthelmintic activity with the extracts at the same concentration in terms of paralysis time and death time of worms. The result revealed the potential usefulness of aqueous and ethanolic extract of Hibiscus rosa-sinensis flower against helminthiasis infection.

About Author:
Ramandeep Kaur
Assistant Professor, CT Institute of Pharmaceutical Sciences,
Jallandhar- 143001
deepraman_18@yahoo.in

ABSTRACT
Phytosomes are little cell like structure which are also termed herbosomes which are formed by complexation of the polyphenolic phytoconstituents in molar ratio with phosphatidylcholine. Bioavailability of flavonoid containing phytomedicines, is reported to be low and erratic due to limited absorption, elevated presystemic metabolism and rapid elimination. But their phytosomal formulations show improved absorption, enhanced delivery and increased bioavailability of phytochemicals than the conventional herbal extracts containing dosage forms. Phytosome technology has been effectively used to enhance the bioavailability of many popular herbal extracts e.g. milk thistle, grape seed, green tea, hawthorn, etc. The improved pharmacokinetic and pharmacological properties of phytosomes make them suitable for the treatment of serious degenerative disorders. This article reviews the recent trends and applications of various herbal extract phytosomes as a tool of drug delivery system and as an emerging technology for increasing bioavailabity of phytoconstituents.

About Author:
Manisha Singh
Sagar Institute of Pharmacy & Technology,
Gandhi nagar, Bhopal (M.P.)
manishamasih85@gmail.com

Abstract
Acalypha indica Linn. consists of dried herb of Acalypha indica Linn. belonging to familyEuphorbiaceae. Within the Euphorbiaceae family, Acalypha indica is one of the biggest and most diverse, with nearly 450 species. Two thirds of its species are found in America, 19 of them in Venezuala, they are mainly used as ornamental, but with the rising of traditional medicine, these species are given medical properties painkillers, laxatives, anti-inflammatory and many others.The GC-MS analysis of methanol and acetone (70 : 30) extract prepared from the whole plant of Acalypha indica linn. revealed the presence of different phytochemicals.

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