September 2012

About Authors:
ANUJ SINGH
VINAYAKA MISSION’S UNIVERSITY
Salem – 636308, Tamil Nadu
anuj.dra@gmail.com

ABSTRACT:-
Healthcare Regulatory Affair Professional with their experience and strong motivation to excel in the Regulatory field has an ability to motivate & give support and strengthen to teams members, involved in process of product registration. Professional has taught a self-starter with the proven ability to prioritize and manage projects in a busy, fast-paced, multitasking environment, along with their experience in establishing relationship with the decision makers & coordinator. The Pharmaceutical industries are among the most highly regulated industries in the country. As India is growing very rapidly in pharmaceutical sector, there is a need of regulatory affairs professionals to cater the current needs of industries for the global competition. Regulatory affairs professionals are the link between pharmaceutical industries and worldwide regulatory agencies. They are required to be well versed in the laws, regulations, guidelines and guidance of the regulatory agencies. There is a growing need to incorporate the current requirements of pharmaceutical industries in the standard curriculum of pharmacy colleges to prepare the students with the latest developments to serve the industries. The present article discusses the regulatory education and its need, learning resources, courses available, syllabus contents and job opportunities in regulatory affairs.

HLL Lifecare Limited is a Mini Ratna Company of Govt. of India under the Ministry of Health & Family Welfare. HLL, a schedule B Public Sector Enterprise is today a multi product, multi unit organization addressing various public health challenges.

Director of Medical Education & Research, Haryana State shall regulate all the Colleges & Schools (in Govt. and Private Sector) relating to Health Education Sector including Ayurveda and Homeopathy Education. The main function of the Directorate will be as under:- Formulate of polices for encouraging quality Medical Education.

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals.

Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products.

PAREXEL has supported the Bio-Tech and Pharmaceutical industries in helping the development of new drugs and treatments on a global basis.

About Authors:
DHIRAJ YADAV
BABU BANARASI DAS UNIVERSITY,
LUCKNOW
dhirajyadav06@gmail.com

ABSTRACT
Miconazole is the antifungal drug, has been used in the treatment of fungal infection of skin and also in yeast infection. In order to decrease the skin rashes, skin irritation, and also for best effect on the skin, miconagol gels have been developed. This study was conducted to develop a gel formulation of miconazole using four types of gelling agents: carbopol, carboxymethylcellulose sodium (Na CMC) and sodium alginate. Effect of penetration enhancer (propylene glycol) on the release has been studied. The gels were evaluated for physical appearance, rheological behaviour, drug release and stability. The drug release from all gelling agents through a standard cellophane membrane was evaluated using Keshary-Chien diffusion cell. All batches of gels showed acceptable physical properties concerning colour, homogeneity, consistency, spreadability and pH value.
Among all the gel formulations, carbopol showed superior drug release than followed by Na CMC, and sodium alginate. Drug release decreased with increase in polymer concentration. Drug release was not linearly proportional with the concentration of penetration enhancer or co-solvents. Stability studies showed that the physical appearance, rheological properties, and drug release remained unchanged upon storage for two months at ambient condition.